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How does smoking affect the immune response in periodontal disease?
↓ Immune response, especially neutrophil function → impaired defence
What vascular change masks bleeding in smokers?
Vasoconstriction
Effect of smoking on periodontal treatment healing?
↓ Healing after periodontal treatment → ↑ tooth mobility & bone loss
What percentage of oral cancers are squamous cell carcinomas?
90%
What increases oral cancer risk alongside smoking?
Alcohol consumption
Common sites of oral cancer?
Lateral tongue, floor of mouth, soft palate
What cellular change leads to malignancy?
DNA mutations in oral epithelial cells → malignant transformation
Key symptom of oral cancer?
Non-healing ulcers
Referral rule for suspected oral cancer?
2-week rule
How does nicotine affect bone healing around implants?
Impairs osteoblast function → poor bone healing
How does microvascular constriction affect implants?
Reduces blood supply to surgical site → ↑ implant failure
Why does smoking delay wound healing?
Carbon monoxide & nicotine ↓ oxygen delivery to tissue
Effect of smoking on fibroblasts & collagen?
↓ Fibroblast activity → delayed epithelialisation & collagen production
Common post-extraction complication in smokers?
Dry socket
Cause of yellow-brown extrinsic staining?
Tar & nicotine (mainly lingual surfaces)
Cause of smoker’s bad breath (halitosis)?
Volatile sulphur compounds + ↓ salivary flow + gingival disease
How does smoking alter oral microbiota?
Shift towards more pathogenic bacteria (e.g. P. gingivalis)
Nicotine effect on plaque?
Promotes biofilm adherence & calcification
Salivary flow in smokers?
Reduced
Why is gingival bleeding reduced in smokers?
Vasoconstriction of capillaries
What is leukoplakia?
White patch that cannot be rubbed off
Which leukoplakia type has higher malignant potential?
Speckled/erythroleukoplakia
Typical appearance of nicotine stomatitis?
Painless grey/white palate with red inflamed duct openings
Is nicotine stomatitis reversible?
Yes, benign & reversible
Common tobacco forms to ask about?
Waterpipes/shisha/hookah, zarda, gutkha, scented chewing tobacco, naswar/nas, chillam, paan, snuff/snus, khaini
What should you ask every patient?
About tobacco use (smoke, paan, snuff, shisha, past use)
What to examine at each visit?
Staining, halitosis, mucosal changes, oral cancer signs, BPE
How to advise at-risk patients?
Offer brief info, avoid confrontation, give quitting resources
Steps if patient is interested in quitting?
Recommend e-cigs/nicotine replacement, refer to local stop-smoking services, record in notes
Steps if patient is not interested in quitting?
Give patient control, keep door open, record in notes, reassess at future visits