9th Grade Cellular reproduction

Chromosomes are condensed DNA.

  • The Centromere is part of chromosome where sister chromatids are held together.

  • 1chromosome = 2 chromatids 

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MITOSIS (ASEXUAL REPRODUCTION)

  • Mitosis’s function is to grow and repair/maintain body.
    • A cell grows, and divides, and repeats during its life.
  • 1 parent cell (46 chromosomes) produces 2 identical daughter cells (46 chromosomes each). 
  • Your cells do not divide (perform mitosis) continually. Most of the time, they are in interphase.
  • Cancer is when cells uncontrollably divide. 

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INTERPHASE (PRE MITOSIS)

  • The cell grows in size and performs regular functions.
  • Chromosomes are replicated (doubled).

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FOUR STAGES OF MITOSIS

  • PMAT : Prophase, Metaphase, Anaphase, Telophase
  • Prophase 
    • Centrioles (poles) appear and move to opposite ends of cell.
    • Spindle fibers form between the poles.
  • Metaphase
    • Chromatids line up in the middle of the cell and attach to the spindle fibers.
  • Anaphase
    • Chromatids separate and begin to move to opposite ends of of the cell.
  • Telophase
    • Two new nuclei form and the chromosomes appear as chromatin (threads rather than rods).
    • Mitosis ends.

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Cytokinesis 

  • Cell membrane moves inward to create two daughter cells (each with its own nucleus and identical chromosomes). 

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MEIOSIS (SEXUAL REPRODUCTION) 

  • Prophase 1

    • Chromosomes line up with their homologous pairs. 
    • Homologous chromosomes are 2 chromosomes that are about the same size & have the same gene type in the same place.
    • Crossing over occurs (homologous pairs transfer their genetic info, creating recombinant chromosomes).
  • Metaphase 1 

    • Chromosomes line up in the middle of the cell in pairs and attach to spindle fibers.
  • Anaphase 1

    • The spindle fibers pull the homologous chromosomes apart and they move to opposite ends of the cell.
  • Telophase 1 and Cytokinesis (ends meiosis one)

    • The nuclear membranes reform around the chromosomes, the two cells are separate.
  • Prophase 2

    • The two haploid cells start to go through meiosis 2.
    • The cells nuclear membrane breaks back down, and spindle fibers begin to form. 
  • Metaphase 2

    • Chromosomes line up in the middle of the cell and attach to spindle fibers (single file).
  • Anaphase 2 

    • Sister chromatids separate and are pulled to opposite sides of the cell by spindle fibers.
  • Telophase 2 and Cytokinesis

    • The nuclear membranes reforms.
    • Four new haploid cells (23 chromosomes) have formed!
    • These cells are gametes, and each one is unique and different from each other (NO identical cells, unlike cells from mitosis). 
  • Nondisjunction occurs when chromosomes don't separate correctly.

    • A cell may receive too many or too little chromosomes in the separation. 

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