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what is the function of arteries
carry blood away from the heart at high pressure
explain how the structure of arteries relates to their function
thick smooth muscle tissue - can contract and control/maintain blood flow/ pressure
thick elastic tissue - can stretch as ventricles contract and recoil as ventricles relax to reduce pressure surges / even out blood pressure / maintain high pressure
thick wall - withstand high pressure/ stop bursting
smooth / folded endothelium - reduces friction
narrow lumen - increases/ maintains high pressure
what is the function of arterioles
division of arteries to smaller vessels which can direct blood to different capillaries/ tissues
explain how the structure of arterioles relates to their function
thicker smooth muscle layers than arteries
contracts - narrow lumen (vasoconstriction) - reduces blood flow to capillaries
relaxes - widens lumens (vasodilation) - increases blood flow to capillaries
thinner elastic layer - pressure surges are lower
what is the function of veins
carry blood back to the heart at lower pressure
explain how the structure of veins relates to their function
wider lumen than arteries - less resistance to blood flow
very little elastic and muscle tissue - blood pressure lower
valves - prevent backflow of blood
what is the function of capillaries
allow efficient exchange of substances between blood and tissue fluid (exchange surface)
explain how the structure of capillaries relates to their function
wall is thin (one cell) layer of endothelial cells - reduces diffusion distance
capillary bed is a large network of branched capillaries - increases surface area for diffusion
smaller diameter / narrow lumen - reduces blood flow rate so more time for diffusion
pores in walls between cells - allow larger substances through
explain the formation of tissue fluid at the arteriole end
higher blood/ hydrostatic pressure inside capillaries than tissue fluid
forcing water out of capillaries
large plasma proteins remain in capillary
explain the formation of tissue fluid at the venule end of capillaries
hydrostatic pressure reduces as fluid leaves capillaries
an increasing concentration of plasma proteins lowers water potential in capillary below that of tissue fluid
water enter capillaries from tissue fluid by osmosis down a water potential gradient
excess water taken up by lymph capillaries and returned to circulatory system through veins
suggest and explain causes of excess tissue fluid accumulation
low concentration of protein in blood plasma or high salt concentration
water potential in capillary not as low - water potential gradient is reduced
so more tissue fluid formed at arteriole end / less water absorbed at venule end by osmosis
high blood pressure - high hydrostatic pressure
increases outward pressure from arterial end AND reduces inward pressure at venule end
so more tissue fluid formed at arteriole end / less water absorbed at venule end by osmosis
lymph system may not be able to drain excess fast enough
what is a risk factor
an aspect of a person’s lifestyle or substances in a person’s body/ environment
that has been shown to be linked to an increased rate of disease
examples for cardiovascular disease
age
diet
high in salt or saturated fat
smoking
lack of exercise
genes