Anatomy
the structure of body parts
Physiology
the function of the body parts
Differentiation
the process by which a cell becomes specialized to perform a specific function (cells differentiate by activating and deactivating genes)
Positive feedback loops
amplify or increase the occurrence of events (ex: breast feeding - stimulates the pituitary gland to produce more prolactin to produce milk)
Negative feedback loop
normal biological response in which the effects of a reaction slow or stop that reaction (ex: when your body temperature rises, causing you to sweat, which then cools you down, bringing your temperature back to normal)
Anatomical position
the body is erect (standing up straight) with feet slightly apart and palms facing forward so that your thumbs point away from the body (prone = face-down supine = face-up)
Axial Portion
head, neck, spine
Appendicular Portion
arms & legs
Viscera
internal organs
Superior (Cranial)
toward the head or upper body (above)
Inferior (Caudal)
away from the head or lower body (below)
Anterior (Ventral)
toward or at the front of the body
Posterior (Dorsal)
toward or at the back of the body
Medial
toward or at the midline of the body (inner side of)
Lateral
away from the midline of the body (outer side of)
Proximal
closer to the origin of the body part or point of attachment of a limb to the trunk
Distal
farther from the origin of a body part of the point of attachment of a limb to the body trunk
Superficial (external)
toward or at the surface
Deep (internal)
away from the body surface
Ipsilateral
same side of the body
Contralateral
opposite sides of the body
Dorsal Cavity
back side
Ventral Cavity
front side
Diaphragm
separates the thoracic and pelvic region
Thoracic Cavity
lungs, heart, thymus gland
Serous Membrane
two layers, covers organs
Parietal
outer layer
Visceral (lines the organs)
inner layer
Pleura
lungs
Pericardium
heart
Peritoneum
organs
Right hypochondriac region
contains the liver and gallbladder, parts of the small intestine, components of the ascending and transverse colon and the right kidney
Umbilical region
The central area of the abdomen that surrounds the umbilicus; it lies inferior to the epigastric region, superior to the suprapubic region, and is bounded laterally by the two lumbar regions
Hypogastric region
a region of the abdomen located below the umbilical region
Right iliac region
located in the lower right abdomen, primarily houses parts of the large intestine (including the cecum and appendix) and is involved in digestion and waste processing
Left hypochondriac region
located in the upper left abdomen, contains parts of the stomach, spleen, pancreas, and left kidney, playing roles in digestion, blood filtration, and immune system support
Left lumbar region
located in the mid-left abdomen, contains parts of the descending colon and the left kidney, contributing to digestion and waste elimination as well as urinary system function
Left iliac region
located in the lower left abdomen, contains parts of the descending colon and sigmoid colon, playing a role in the final stages of digestion and waste elimination
Epigastric region
located in the upper central abdomen, contains parts of the stomach, liver, pancreas, and duodenum, playing a key role in digestion and metabolic processes
Phospholipid
a type of lipid molecule that consist of a hydrophilic (water-attracting) phosphate head and two hydrophobic (water-repelling) fatty acid tails, forming the primary structural component of cell membranes by creating a bilayer that separates the cell's internal and external environments
Active transport
the movement of molecules or ions across a cell membrane against their concentration gradient, requiring energy input in the form of ATP and often involving protein pumps
Passive transport
the movement of molecules or ions across a cell membrane without the use of cellular energy, occurring along their concentration gradient and including processes like diffusion and osmosis
Diffusion
a type of passive transport where molecules move from an area of higher concentration to an area of lower concentration until equilibrium is reached
Solute
a substance that is dissolved in a solvent to form a solution, such as salt or sugar in water
Solvent
the substance, usually a liquid, that dissolves a solute to form a solution, with water being the most common example
Concentration gradient
the difference in the concentration of a substance between two regions, driving the movement of molecules during processes like diffusion and osmosis
Osmosis
the passive movement of water molecules across a selectively permeable membrane from an area of lower solute concentration to an area of higher solute concentration, aiming to equalize solute concentrations on both sides of the membrane
Isotonic
has an equal concentration of solutes compared to another solution, resulting in no net movement of water across a selectively permeable membrane
Hypotonic
has a lower concentration of solutes compared to another solution, causing water to move into the area with higher solute concentration (often into a cell), potentially leading to swelling or bursting
Hypertonic
has a higher concentration of solutes compared to another solution, causing water to move out of the area with lower solute concentration (often out of a cell), potentially leading to shrinkage or dehydration
Tonicity
the relative concentration of solutes in a solution, influencing the direction of water movement across a selectively permeable membrane, and determining whether the solution is isotonic, hypotonic, or hypertonic
Sodium-potassium exchange pump
an active transport mechanism that moves sodium ions out of a cell and potassium ions into the cell, both against their concentration gradients, using energy from ATP to maintain cellular function and homeostasis
Endocytosis
a process by which cells engulf external substances, forming a vesicle to bring them into the cell
Exocytosis
the process by which cells expel substances by vesicles fusing with the cell membrane, releasing their contents outside the cell
Phagocytosis
a type of endocytosis where cells, typically white blood cells, engulf large particles, such as pathogens or debris, and digest them
Pinocytosis
a type of endocytosis where the cell engulfs extracellular fluid and dissolved solutes into small vesicles, often referred to as "cell drinking”
Renal cortex
the outer region of the kidney, containing the renal corpuscles and the proximal and distal convoluted tubules, playing a key role in filtration and reabsorption
Renal medulla
the inner region of the kidney, consisting of renal pyramids and involved in the concentration of urine through the loops of Henle and collecting ducts
Renal pelvis
a funnel-shaped structure in the kidney that collects urine from the renal calyces and channels it into the ureter for transport to the bladder
Kidney
a pair of vital organs in the urinary system that filter blood to remove waste products and excess substances, regulate fluid and electrolyte balance, and produce urine, which is excreted from the body. The kidneys also play roles in regulating blood pressure, red blood cell production, and calcium metabolism
Nephron
functional unit of the kidney
Afferent arteriole
a small blood vessel that carries blood into the glomerulus of the kidney, where filtration occurs
Efferent arteriole
carries blood away from the glomerulus after filtration has taken place, leading to the peritubular capillaries
Glomerulus
a network of capillaries in the kidney where blood filtration begins, allowing water, salts, glucose, and waste to pass into the Bowman's capsule
Proximal convoluted tubule
the first segment of the renal tubule, where the majority of reabsorption of water, ions, and nutrients from the filtrate occurs
Loop of Henle
a U-shaped portion of the renal tubule responsible for creating a concentration gradient in the kidney, which helps concentrate urine and reabsorb water and sodium
Distal convoluted tubule
the segment of the renal tubule where further reabsorption of sodium and water occurs, and where secretion of potassium and hydrogen ions happens
Collecting duct
the final part of the renal tubule, where urine is concentrated by the reabsorption of water, and it channels urine into the renal pelvis
Peritubular capillaries
small blood vessels that surround the renal tubules, facilitating the exchange of substances between the tubules and blood, such as reabsorption of water and nutrients
Urinalysis
a diagnostic test that examines the physical, chemical, and microscopic properties of urine to assess overall health and detect conditions such as infections, kidney disease, diabetes, and urinary tract disorders. It typically includes measurements of color, clarity, pH, specific gravity, protein, glucose, ketones, and the presence of cells or microorganisms
Urinary bladder
a hollow, muscular organ that stores urine produced by the kidneys until it is excreted from the body
Urethra
a tube that connects the urinary bladder to the outside of the body, allowing urine to be expelled during urination
Retroperitoneally
the location of certain organs that lie behind (or posterior to) the peritoneum, the membrane lining the abdominal cavity. These organs, such as the kidneys, adrenal glands, and pancreas, are not surrounded by the peritoneal cavity but are positioned between the peritoneum and the posterior abdominal wall
Renal sinus
the hollow region within the kidney that houses the renal pelvis, major and minor calyces, blood vessels, nerves, and fatty tissue
Minor calyx
a large, funnel-shaped structure in the kidney that collects urine from several minor calyces and channels it into the renal pelvis
Minor calyx
a smaller, cup-like structure in the kidney that receives urine from the renal papillae (tips of the renal pyramids) and funnels it into the major calyces
Renal pyramid
a cone-shaped structure in the renal medulla of the kidney, containing the loops of Henle and collecting ducts, and is involved in urine concentration
Ureter
a muscular tube that carries urine from the renal pelvis of the kidney to the urinary bladder for storage before excretion
Renal artery
a blood vessel that supplies oxygenated blood to the kidneys, branching off from the abdominal aorta and delivering blood to the kidneys for filtration
Renal vein
a blood vessel that carries deoxygenated blood away from the kidneys and drains it into the inferior vena cava, after the kidneys have filtered waste products from the blood
Aorta
the largest artery in the body, originating from the left ventricle of the heart, and carrying oxygenated blood to the rest of the body through its various branches
Inferior vena cava
a large vein that carries deoxygenated blood from the lower half of the body to the right atrium of the heart
Secretion
the process by which substances, such as ions, waste products, and drugs, are actively transported from the blood into the renal tubules, eventually becoming part of the urine
Reabsorption
the process by which essential substances like water, glucose, and ions are absorbed from the renal tubules back into the blood, preventing their loss in urine
Micturition
the process of urination, where urine is expelled from the urinary bladder through the urethra to the outside of the body, controlled by both voluntary and involuntary muscle contractions
Catheterization
a medical procedure in which a catheter (a thin, flexible tube) is inserted into the body, typically into the bladder through the urethra, to drain urine or administer fluids or medications. It is commonly used when a patient is unable to urinate naturally due to medical conditions or surgery
Kidney stones
minerals form inside the kidney and must pass through the ureter (PAINFUL)
Cytisis
bacteria enters the bladder or kidneys
Overactive bladder
sudden contractions of bladder produce sensation of urgency
Incontinence
inability to control urination (or defcation)
Dialysis
a treatment that filters a person's blood when their kidneys are no longer working properly
Loose connective tissue
the stretchable fascia between organs-like an elastic glue spread between organs
Adipose connective tissue
fat storage under the skin; important for protection and insulation
Reticular connective tissue
web like fibers of the lymphatic(immune) system; helps filter blood and contains white blood cells to destroy dangerous invaders
Dense connective tissue
tendons and ligaments—flexible but strong
-tendon-connects muscle to bone
-ligament-connects bone to bone
Bone tissue (osteocytes)
osteoblast—bone building cell
osteoclast—bone destroying cell
^work together and can reshape this tissue
Hyaline cartilage
shiny and smooth, at the ends of bones (lining of joints)
Fibrocartilage
strongest and most durable, “shock absorbers” (intervertebral discs, meniscus of the knee joint)
Elastic cartilage
most flexible cartilage (ears, nose, larynx)
Erythrocytes
red blood cells: carry oxygen (some carbon dioxide)