Hematology/Oncology MKSAP

Treatment of asymptomatic essential thrombocytosis is ________ in those under 60. Treatment is _____ over the age of 60.

Treatment of asymptomatic essential thrombocytosis is aspirin in those under 60. Treatment is aspirin + hydroxyurea over the age of 60.

Cytoreductive therapy incudes ____

Cytoreductive therapy incudes hydroxyurea, interferon, and anagrelide.

Ruxolitinib is an oral JAK1/JAK2 inhibitor approved for use in _____ and ______.

Ruxolitinib is an oral JAK1/JAK2 inhibitor approved for use in polycythemia vera and myelofibrosis

What is your differential for pure red cell aplasia?

PATTERNS”

• P: Parvovirus B19 infection

• A: Autoimmune diseases

• T: Thymomas

• T: Tumors (solid tumors, malignancies)

• E: Epilepsy meds (e.g., phenytoin)

• R: Red cell aplasia (Diamond-Blackfan anemia)

• N: Non-Hodgkin lymphomas (malignancies)

• S: Solid tumors (again, for malignancies)

Using "PATTERNS" links to the variety of causes in PRCA, showing how it’s a condition with different causes following similar “patterns.”

Describe the anatomical placement of the GSV, CFA, CFV

For patients with low-risk neutropenic favor (asymptomatic), the most appropriate treatment is _______.

Ciprp + Augmentin