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Psychosis
Significant loss of contact with reality
Hallmark of Schizophrenia
Schizophrenia - Prevalence
Lifetime: 1%
Male
Onset: ages 18-30
Delusions
Erroneous belief
Disturbance in content of thought
Fixed and firmly held despite clear contradictory evidence
Hallucinations
Sensory experience
Seems real but occurs in absence of any external perceptual stimulus
Can occur in any sensory modality
Disorganized speech - Schizophrenia
Failure to make sense
Despite conforming to semantic and syntactic rules of speech
Disorganized behavior - Schizophrenia
Impairment of goal-directed activity
Occurs in areas of daily functioning
Catatonia
Catatonia stupor
Paranoid Schizophrenia
Absurd, illogical organized beliefs
Disorganized Schizophrenia
Disorganized speech & behavior; flat or inappropriate affect
Catatonic Schizophrenia
Pronounced motor signs that reflect great excitement or stupor
Shizoaffective Disorder
Features of schizophrenia and severe mood disorder
Brief psychotic disorder
Sudden onset of psychotic symptoms or disorganized speech or catatonic behavior
Delirium
State of acute brain failure that lies between normal wakefulness and stupor or coma
Delirium - Clinical
Has sudden onset and involves fluctuating state of reduced awareness
Reflects confusion, disturbed concertation, and cognitive dysfunction
Can occur at any age, elder and children higher risk
May result from drugs, withdrawal, head injury, or infection
Delirium - Treatments
Often reversible
Most often treated by medications, environmental manipulations, and family support
Dementia - Clinical
Not rapidly fluctuating condition
Characterized by a decline from previously attained level of functioning
Slow onset and deteriorating course
Cause by over 50 different disorders
Most commonly caused by Alzhemier’s
Parkinson’s - Clinical
Second most common neurodegenerative disorder
Characterized by tremors or rigid movements
Primarily caused by loss of dopamine neurons
About 75% eventually show signs of dementia before passing
Huntington’s - Clinical
Rare degenerative disorders of nervous system
Chronic, progressive chorea (Involuntary movements)
Patients usually develop dementia
Alzheimer’s
Progressive and fatal neurodegenerative disorder
Usually slow but progressively deteriorating course terminating in delirium and death
Alzheimer’s - Risk factors
Age
Genes
Alzheimer’s - Neuropathology
Atrophy - Brain Shrinkage with older age
Plaques - Build-up on Axons; struggles to function
Neurofibrillary tangles - myelin sheath deteriorates, causes tangles
Impaired social cognition
Difficulty recognizing emotion in facial expression or speech
Psychosocial treatments - Schizophrenia
Family therapy
Case management
Social-skills training
Cognitive remediation
Cognitive-behavioral therapy
Separation anxiety disorders - children
Excessive anxiety about separation from major attachment figures such as the Mother and familiar home surroundings
Characteristics of Anxiety disorders in Childhood/Adolescence
Unrealistic fears
Oversensitivity
Self-consciousness
Nightmares
Chronis Anxiety
Childhood Depression
Occurs with high frequency
Depressed mood can be replaced by irritability
Childhood Bipolar disorder
Extreme mood swings and aggressive, irritable behavior
Increasingly diagnosed in children and adolescents
Vascular Disease
Series of circumscribed cerebral infarcts cumulatively destroy neuron over expanding brain regions