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skeletal muscle
voluntary, attached to bones
cardiac muscle
involuntary, striated, walls of heart
smooth muscle
involuntary, non striated, walls of hollow organs
functions of muscles
excitatory, contractility, extensibility, elasticity, movement, body posture, stabilize joints
what is an action potential?
message sent down axon through excitable membranes
what is resting membrane potential?
the charge of a muscle membrane when no action potential is occurring; -70mV; kept stable by diffusion
what is depolarization?
all sodium gates open
what is repolarization?
sodium gates close, potassium gates open
what is hyperpolarization?
too much potassium after repolarization is fixed by sodium-potassium pumps
2 types of gated ion channels
chemically-gated ion channels and voltage-gated ion channels
parts of a skeletal muscle
tendon, epimysium, perimysium, fascicle, endomysium, muscle fiber, sarcolemma, myofibril, myofilament, mitochondria, sarcoplasm, sarcoplasmic reticulum, glycosome, myoglobin, T-tubule, actin, myosin, triad
parts of a sarcomere
H band, A band, I band, Z line, M line, actin, myosin, myosin head, ATP binding site, tropomyosin, troponin C, troponin T, troponin I, dystrophin, titin/connectin, actin binding site
parts of a neuromuscular junction
axon, axon terminal, sarcolemma, synaptic cleft, synaptic vesicle, Ach, Ach receptor, calcium channels, SNARE, acetylcholinesterase
how does an action potential travel from the sarcolemma to the muscle fibers?
Ach binds to receptors, opens sodium/potassium gates, sends action potential from sarcolemma along T-tubules to muscle fibers
events at neuromuscular junction
action potential reaches axon terminal, opens calcium gates, calcium causes Ach to be released, Ach diffuses across synaptic cleft and binds to receptors, causes ion channels to open and create action potential, acetylcholinesterase breaks down Ach in synaptic cleft
excitation-contraction coupling stage of action potential
action potential hits terminal cisternae, opens calcium gates, calcium binds troponin, tropomyosin moves to expose myosin binding sites