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5 factors that contribute to the life of a theory
accountability
explanatory reference
testability
predictability
parsimonious
accountability
accounts for most of the data
explanatory reference
explanation must offer good grounds for believing that the phenomena would occur under the specific conditions
testability
verifiable and falsifiable
predict
predict phenomena beyond those for which the theory was originally designed
parsimonious
adopts the fewest/simplest set of assumptions
rationalism
using reason and logic to seek universal truths; rely on deductive reasoning
empiricism
observation is basis for understanding; knowledge is gained through experience; rely on inductive reasoning
research
systematic investigation; collecting and analyzing data for a purpose; experimentation aimed at the discovery and interpretation of results, revision of accepted theories or laws, or practical applications of such new or revised theories or laws
3 goals of research
control
understand
predict
5 major characteristics of the scientific approach
empirical referent, public/objective, repeatable, self-correcting, falsifiable
primary source
original source of research findings
secondary source
describes, explains, or interprets information contained in primary sources
tertiary source
various sources used to provide a broad overview of a topic
describe the scientific method
descriptive research
describes the current status of a phenomena; used to generate a hypothesis
analytical research
tests a hypothesis
qualitative research
systematically describes the current status of a phenomena; observations of what others do or say; focus on meaning and gaining a deeper understanding; a subjective research approach; focus on the way people interpret and make sense of their experiences
quantitative research
systematic process in which data is numerically quantified
null hypothesis
H0; default hypothesis; hypothesis that the investigator wants to reject; states that there is no differece
alternative hypothesis
H1; hypothesis attempted to be supported by investigational findings; states that differences exist
independent variable
what is being manipulated; experimental variable
dependent variable
effect of manipulation; outcome variable
"P" in PICOTS
population, patient, problem
"I" in PICOTS
intervention, issue
"C" in PICOTS
comparison, alternative therapeutic strategy
"O" in PICOTS
outcome
"T" in PICOTS
time frame
"S" in PICOTS
setting
phenomenology
subjective experiences; we can only know how things appear and never how they really are
advantages of qualitative resesarch
Focus on subjective aspects; Avoids biases inherent in quantitative approaches; In-depth examination of something; Useful for building new theories/exploring new areas of research; Dynamic and flexible; Naturally occurring environment; Fewer restrictions; Smaller sample size; Respondents provide data in their own words
disadvantages of qualitative research
Not easily generalizable Not easily replicated Lots of data that is difficult to analyze Time consuming Biases from researcher/respondent Subjective data interpretation Dependent upon researcher's skill level Small sample size Unable to establish causality
sampling techniques
convenience snowball purposeful critical case homogeneous criterion quota extreme cases typical cases maximum variation conforming/disconforming
convenience sampling
readily available participants
snowball sampling
referrals from other participants
purposeful sampling
based on emerging findings during the study
critical case sampling
participants likely to have the greatest impact
homogeneous sampling
participants with something in common
criterion sampling
participants who meet certain criteria
extreme case sampling
most extreme participants are chosen
typical case sampling
illustrate what is typical or average
maximum variation sampling
wide range of variation in participants
conforming/disconforming sampling
support or disagree with emerging explanation of findings
benefit of using open-ended questions
require more than one-word or few-word responses; encourage full, meaningful answers
3 advantages of a focus group
synergism
snowballing
stimulation
synergism
similar individuals are more likely to provide richer insight and foster new ideas
snowballing
one individual's comments trigger a chain reaction from other participants
stimulation
as discussion begins, level of excitement endures and individuals want to participate
open coding
data is initially placed into broad categories; subcategories are identified
axial coding
systematically examine coded data to discover relationships within and across categories; identify main themes (larger categories)
types of qualitative designs
narratives case study phenomenological study grounded theory ethonography
narrative
collecting and assembling stories from personal experiences of an individual or small group
case study
detailed analysis of 1+ individuals, groups, or institutions
case study advantages
detailed analysis
case study disadvantages
small sample size; poor generalizability; sampling bias
phenomenological study
study of individuals' lived experiences
grounded theory
developing a new theory from a corpus of data acquired by the observer
grounded theory advantages
can generate the theory during the research instead of having preconceived notions
grounded theory disadvantages
must not come with preconceived notions; must be flexible
ethnography
study of group culture
ethnography disadvantages
time consuming, requires patience
phases of SSD
baseline or withdrawal: no intervention intervention intervention 2
retrospective
use data that already exists (outcome is known); ex: medical chart review; looking back in time; less costly; shorter duration; reliance on memory/quality of information
prospective
follows participants over time; more costly; longer duration; attrition; less vulnerable to bias
case report
only one participant; very detailed description of an individual; uses descriptive statistics
case series
more than one participants who share something in common; describes characteristics or similarities; identify new disease/syndrome; describes disease progression; uses descriptive statistics
case control
case matched with a control; case is identified and a control participant is selected from same source population (must be similar to case); beneficial for rare disease/condition; can calculate risk and rate ratios
SSD
establish causal relationships in one or few subjects; series of observations over time
cohort
follows participants over time; can be closed or open
cross sectional
measures participants from representative sample at one point in time
RCT
randomly allocates participants to receive experimental condition or control condition; true experimental design characterized by manipulation, randomization, and control
randomization
each participant has an equal chance of being assigned to any group
advantages of randomization
assignment is independent of judgement bias; known and unknown variables are more likely to be balanced between groups; the larger the size, the more balanced the groups will be
control group advantages
rules out the influence of potential confounding variables; helps attribute "new" treatment to differences between experimental and control groups
single blinding
patients OR investigators are blind to their treatment assignment
double blinding
patients AND investigators are blind to their treatment assignment
triple blind
patients, investigators administering treatment, and investigators measuring response to treatment are blind to treatment assignment
what is the difference between experimental and quasi-experimental design?
randomization is used in experimental
mixed methods definition
combines qualitative and quantitative methods; uses induction, deduction, and abduction reasoning; different approaches provide different viewpoints
5 purposes of using a mixed methods design
triangulation
complementary
expansion
initiation
development
triangulation
both methods are used to study the same concept; focus on similarities and corroboration of results
complementary
one method is dominant and the other is used to enhance/clarify findings; focus on elaboration
expansion
different methods are used for different study components; expand breadth and range of research
initiation
discover contradictions leading to reframing of research question
development
findings from one method are used to help inform findings from the other method
equivalent vs dominant
dominant: one method is more dominant than the other, putting more emphasis on that type of design
equivalent: both methods are equally a part of the study
sequential exploratory vs sequential explanatory
sequential exploratory: qualitative first followed by quantitative; purpose is to explore relationships
sequential explanatory: quantitative first followed by qualitative; purpose is to explain relationships
systematic review
a systematic approach to reviewing, critically appraising, and synthesizing literature; clearly stated objective; pre-determined eligibility criteria; systematic search; assessment of validity of findings; systematic presentation of findings
meta-analysis
quantitative, formal, epidemiological study designed to systematically assess results of previous research to derive conclusions; pulls all data together from more than one study and analyzes it as a whole; estimate of treatment effect
forest plot
graphical display of the statistical results of a meta-analysis; shows odds ratios and confidence intervals
Type I error
false positive; incorrect rejection of the null; set alpha level
Type II error
false negative; not rejecting the null when the alternative hypothesis is supported; power of study (beta)
one-tailed testing
directional testing; predicts a difference in a particular direction; alpha is all in one tail
two-tailed testing
predicts that a difference exists, but not in a particular direction; alpha is split equally between tails
statistical significance
difference observed is above chance
clinical significance
demonstrable functional change
power
probability that you will predict if a difference exists; reduce risk of Type II error by having enough power
effect size
scale free, standardized values that provide an indication of the extent to which the value of a DV is explained by the IV
sample size
number in a study; representative portion of a population
validity
degree to which a test measures what it is supposed to measure