Nucleophiles and Bases
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14 Terms
1
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C-, N-, O-, charge trapped
Good Nucleophile Strong Base
2
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OH-, OR-, NR2-, -C-=CR
Good Nucleophile Strong base
3
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O-. C-, N-, charge delocalized
Good Nucleophile Weak Base
4
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Bulky Atoms
T-Butoxide, LDA
5
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-OC(CH3)3, -NC2(CH3)4
Poor Nucleophile, Strong Base
6
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H2O, Neutral O Species, HOCH3
Bad Nu, Weak Base
7
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Poor Nu Weak Base - 2*, 3*
Sn1/E1 Reaction
8
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Poor Nu Weak Base - Below 2*
No reaction
9
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Good Nu Weak Base - 3*
Sn1/E1G
10
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Good Nu Weak Base - Below 3*
Sn2
11
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Good Nu Strong Base - methyl/1* unhindered
Sn2
12
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Good Nu Strong base - everything else
E2
13
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Poor Nu Strong Base - methyl
Sn2
14
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Poor Nu Strong Base
E2
Note 
Flashcards (44)