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Neuron
Nerve cell, basic unit of the nervous system, each composed of receptive extensions (dendrites), cell body, conducting axon & transmitting axon terminal
Glial cell
Glia, nonneuronal brain cells that provide structural, nutritional & other types of support to the brain
Synapse
Cellular location at which information is transmitted from a neuron to another all
Input zone
Part of the neuron that receives information from other neurons / specialized sensory structures
Dendrite
An extension of the cell body that receives information from other neurons.
Integration zone
Part of a neuron that initiates neural electrical activity
Cell body (soma)
Region of a neuron that is defined by the presence of the cell nucleus
Axon (nerve fiber)
A single extension from the nerve cell that carries action potentials from the cell body toward axon terminals
Axon collateral
Branch of axon.
Output zones
Part of a neuron at which the cell sends information to another all
Axon terminal (bouton)
End of an axon or axon collateral which forms a synapse onto a neuron/other target all; serves as output zone
Dendritic spines
Small projections from the surface of the dendrite that add additional space for synapses; receives additional synaptic inputs; neuron's soma integrates/combines the information that has been received to determine whether or not to send a signal of its own
Conduction zones
Axon carries the neuron's own electrical signals away from the cell body
Motor neuron
Transmits neural messages to muscles/glands
Sensory neuron
Nerve cell that is directly affected by changes in environment (light, touch, odor…)
Interneuron
Nerve cell that is neither a sensory or motor neuron; receive input from & send output to other neurons
Multipolar neuron
Nerve cell with many dendrites & a single axon
Bipolar neuron
Nerve cell that has a single dendrite at one end & a single axon at the other end
Unipolar neuron (monopolar)
Nerve cell with a single branch that leaves the cell body & extends in 2 directions; one end input & other is output
Presynaptic
"Transmitting" side of a synapse
Postsynaptic
Region of a synapse that receives & responds to the neurotransmitter
Presynaptic membrane
Specialized membrane on the axon terminal of a nerve cell that transmits information by releasing neurotransmitters
Synaptic cleft
The space between the presynaptic & postsynaptic neurons at a synapse
Postsynaptic membrane
Specialized membrane on the surface of a neuron that receives information by responding to neurotransmitter from a presynaptic neuron.
Synaptic vesicle
Small, spherical structure that contains molecules of neurotransmitters
Neurotransmitter (synaptic/chemical)
Chemical released from the presynaptic axon terminal that serves as basis of communication between neurons.
Neuroplasticity
Ability of the nervous system to change in response to experience / environment
Axon hillock
Cone-shaped area on the cell body from which the axon originates
Innervate
To provide neural input to
Anterograde transport
Moves materials toward the axon terminals
Retrograde transport
Moves axonal used materials back to the cell body for recycling
Axonal transport
Transportation of materials from the neuronal cell body toward the axon terminals & from the axon terminals toward the cell body.
Oligodendrocytes
Type of glial cell that forms myelin in the central nervous system
Schwann cell
Type of glial cell that forms myelin in the peripheral nervous system.
Myelin
Fatty insulation around an axon, formed by glial cells; boosts the speed at which nerve impulses are conducted
Node of Ranvier
A gap between successive segments of the myelin sheath where the axon membrane is exposed
Astrocyte
Star-shaped glial cell with numerous processes (extensions) that run in all directions
Microglial cell
Extremely small motile glial cells that remove cellular debris from injured / dead cells
Gross neuroanatomy
Anatomical features of the nervous system that are apparent to the naked eye
Central nervous system (CNS)
Portion of the nervous system that includes brain & spinal cord
Peripheral nervous system (PNS)
Portion of the nervous system that includes all the nerves & neurons outside the brain & spinal cord
Nerve
Collection of axons bundled together outside the central nervous system
Motor nerve
A nerve that transmits information from the CNS to the muscles & glands
Sensory nerve
A nerve that conveys information from the body to the CNS
Somatic nervous system
A part of the PNS that supplies neural connections mostly to skeletal muscles & sensory systems of the body (cranial nerves & spinal nerves)
Autonomic nervous system
A part of the PNS that provides the main neural connections to the internal organs.
Cranial nerve
A nerve that is directly connected to the brain.
Spinal nerves
A nerve that emerges from the spinal cord.
Cervical
Topmost 8 segments of the spinal cord; in neck region
Thoracic
12 spinal segments below the cervical (neck) portion of the spinal cord; in the torso
Lumbar
5 spinal segments in the upper part of the lower back
Sacral
5 spinal segments in the lower part of the lower back
Coccygeal
Lowest spinal vertebra (coccyx, tailbone)
Sympathetic nervous system
Part of the autonomic nervous system that generally prepares the body for action
Parasympathetic nervous system
Part of the autonomic nervous system that generally prepares the body to relax/recuperate
Sympathetic ganglia
Small clusters of neurons found outside the CNS.
Sagittal plane
Plane that divides the body or brain into right & left portions
Coronal plane (frontal/transverse)
Plane that divides the body or brain into front & back portions
Horizontal plane
Plane that divides the body or brain into upper & lower portions.
Medial
Toward the middle
Lateral
Toward one side
Ipsilateral
A location on the same side of the body.
Contralateral
A location on the opposite side of the body.
Superior
Above
Inferior
Below
Basal
Toward the base / bottom of a structure
Anterior (rostral)
Toward the head end of an organism
Posterior (caudal)
Toward the tail end of an organism
Proximal
Near the trunk / center of an organism
Distal
Toward the periphery of an organism or end of a limb
Afferent
Carrying an action potential toward the brain, or toward one region of interest from another region of interest
Efferent
Carrying an action potential away from the brain, or away from one region toward another
Dorsal
Back of body, top of brain.
Ventral
Toward the belly or front of the body, bottom of brain
Gray matter
Areas of the brain that are dominated by cell bodies & devoid of myelin, mostly receives & processes information
White matter
Light-coloured layer of tissue, consists mostly of myelin sheathed axons that lies underneath the gray matter of the cortex, mostly transmits information
Cerebral hemisphere
One of the 2 halves - right or left - of the forebrain
(Cerebral) cortex
Outer covering
Gyrus
Ridged or raised portion of the cortical surface
Sulcus
Crevice or valley of the cortical surface
Frontal lobe
The most anterior portion of the cerebral cortex.
Parietal lobe
Large region of cortex lying between the frontal & occipital lobes in each cerebral hemisphere
Temporal lobe
Large lateral region of cortex in each cerebral hemisphere; continuous with the parietal lobe posteriorly & separated from frontal by Sylvian fissure
Occipital lobe
Large region of cortex that covers much of the posterior part of each cerebral hemisphere
Sylvian fissure (lateral sulcus)
A deep fissure that demarcates the temporal lobe
Central sulcus
A fissure that divides the frontal lobe from the parietal lobe
Corpus callosum
Main band of axons that connect the 2 cerebral hemispheres
Postcentral gyrus
Strip of parietal cortex, just posterior to the central sulcus that receives somatosensory information from the entire body
Precentral gyrus
Strip of frontal cortex, just anterior to the central sulcus that is crucial to motor control
Neural tube
An embryonic structure with subdivisions that corresponds to the future forebrain, midbrain, & hindbrain
Forebrain
The frontal division the neural tube, containing the cerebral hemisphere, thalamus, & hypothalamus
Midbrain
Middle division of the brain.
Hindbrain
Rear division of the brain, which in mature vertebrate contains the cerebellum, pons, & medulla
Telencephalon
Anterior part of the fetal forebrain, which will become the cerebral hemispheres in the adult brain
Diencephalon
Posterior part of the fetal forebrain, which will become the thalamus & hypothalamus in the adult brain.
Brainstem
Region of the brain that consists of the midbrain, pons, medulla
Nucleus
A collection of neuronal cell bodies within the central nervous system
Tract
Bundle of axons found within the central nervous system.
Pyramidal cell
Type of large nerve cell that has a roughly pyramid-shaped cell body & is found in the cerebral cortex
Cortical column
One of the vertical columns that constitute the basic organization of the cerebral cortex