D. tissue tolerances to radiation (radiation safety)

what’s TD 5/5

dose of radiation to healthy tissue that will cause a 5% chance of complication within five years of the delivered dose

what are the 4 R’s

repopulation

redistribution

repair of sublethal damage

reoxygenation

remaining cells undergo, mitosis, and repopulate tissues

Repopulation

which one is unfavorable for malignant tumor cells?

repopulation

remaining cells transition to a different cycle of mitosis after irradiation

redistribution

healthy tissues repair the radiation damage when adequate oxygen is available

repair

(T/F) malignant tumor cells are more hypoxic than normal tissues, and therefore they do not easily repair themselves

T

hypoxia tumor cells become more oxygenated and therefore more radiosensitive, which allows for more of the tumor to be destroyed

reoxygenation

(T/F) pacemakers should never be directly in the path of the radiation

T

the AAPM suggests to keep doses btw ?-? Gy

2-5 Gy

The ratio of the radiation dose needed to cause damage without a chemotherapy drug compared to the radiation dose needed with the chemotherapy drug

dose effect factor (DEF)

(T/F)

The DEF is greater than one when chemotherapy drugs have a sensitizing effect

T