Common GPCR Signaling Pathways

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4 Terms

1
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What enzyme does Gs activate?

Adenylyl cyclase.

2
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What does adenylyl cyclase produce?

Cyclic AMP (cAMP).

3
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What does cAMP do?

It activates protein kinase A (PKA), which phosphorylates proteins to cause a cellular response.

4
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What enzyme does Gi inhibit?

Adenylyl cyclase, reducing cAMP levels and decreasing cell activity.