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what does the endocrine system do?
work with the nervous system to maintain homeostasis
what are hormones
chemical messengers produced by the endocrine glands and secreted directly into the bloodstream
when do hormones produce effects?
when they find their specific receptors in or on cells
a cell that has receptors for a particular hormone is called a ____
target
what 3 things control hormone secretion?
Feedback systems
Direct stimulation from nervous system
Levels of certain chemicals in the blood
Explain negative feedback
increase of plasma hormones causes the hypothalamus to decrease releasing factors which decrease trophic hormone from the pituitary gland which causes target organ activity and decrease of plasma hormones
what is an example of positive feedback?
oxytocin
What are the major endocrine glands?
hypothalamus, pituitary, thyroid, parathyroid, adrenal, pancreas, testis, and ovaries
what does the hypothalamus control?
appetite control, body temperature regulation, wake-sleep cycles
what is the hypothalamus a bridge between?
the nervous and endocrine system
explain the portal system
modified neurons in the hypothalamus which secrete releasing and inhibiting factors into tiny blood vessels
what does the portal system communicate with?
the anterior pituitary
what do modified neurons in the hypothalamus also produce?
antidiuretic hormones and oxytocin
ADH and Oxytocin are transported to the ____ pituitary and stored
posterior
the master endocrine gland is composed of 2 separate glands which are:
the anterior pituitary and the posterior pituitary
what is the hypothalamic pituitary axis
communicates with the pituitary gland in response to environmental stimuli, changes in homeostasis, and stress, and this neuroendocrine communication is referred to as that
what are the hormones produced from the anterior pituitary
Growth Hormone, Prolactin, TSH, ACTH, FSH, LH
what is prolactin
helps and maintains lactation. release continues as long as the teat is stimulated by nursing/milking
what is the thyroid-stimulated hormone?
stimulates growth and development of the thyroid gland and causes it to produce hormones. regulated by negative feedback from the thyroid gland.
what is the ACTH hormone
stimulates growth and development of the cortex of the adrenal gland and releases some of its hormones. regulated by the negative feedback of the adrenal cortex. can also be released quickly as a result of stimulation of the hypothalamus by other parts of the brain.
what is the follicle-stimulating hormone in females?
stimulates the growth and development of follicles in the ovary. stimulates the lining cells of the follicles to produce and secrete estrogens
what does the follicle-stimulating hormone do in males?
stimulate spermatogenesis
what is the luteinizing hormone in females?
completes the process of follicle development in the ovary. estrogen from the follicle feedbacks on the pituitary and FSH decreases (neg. feedback) and LH increases (pos feedback)
LH peaks resulting in ovulation. After ovulation, LH stimulates cells in the empty follicle to multiple and develop into the corpus luteum.
What is the corpus luteum
produces progesterone which is necessary to maintain pregnancy
What does the luteinizing hormone do in males?
LH stimulates cells in the testes (interstitial cells) to develop and produce testosterone.
What is the posterior pituitary?
-no production of hormones
-stores antidiuretic hormone and oxytocin produced by the hypothalamus
-hormones are released when the posterior pituitary receives nerve impulses from the hypothalamus
what are antidiuretic hormones?
helps prevent the loss of large amounts of water in urine.
antidiuretic hormones cause what?
kidneys to reabsorb more water from the urine- conserves water and concentrates urine
when is antidiuretic hormone released
when the hypothamus detects a water shortage
Deficiency of ADH causes what?
diabetes insipidus
What is oxytocin
causes the uterus to contract at the time of breeding and at partuition. also causes milk let down
where is the thyroid gland located
on either sides of the trachea
what 2 hormones does the thyroid gland produce?
the thyroid hormone and calcitonin
what is the function of calcitonin?
helps lower blood calcium levels
what is the thyroid gland a collection of?
follicles that are lined by simple cuboidal or columnar epithelium
what are the follicles filled with?
cuboidal, gel-like substance that consists of protein/ iodine complex
Thyroid hormone is produced when stimulated by _____ from the ______ pituitary
the thyroid stimulating hormone
from the anterior pituitary gland
calcitonin inhibits what
the action of osteoclasts and works opposit of the parathyroid hormone
what is the parathyroid hormone
helps prevent hypocalcemia. causes kidneys to retain calcium and the intestines to absorb calcium from food. and withdraws calcium from the bones
what are adrenal glands
small glands located near the cranial ends of the kidneys. consists of the adrenal cortex and the adrenal medulla
what is the adrenal cortex?
develops from glandular tissue.
The adrenal cortex Production stimulated by ____ from the ________ pituitary
by the ACTH
from the anterior
what is glucocorticoid hormones
includes cortisol and corticosterone
-hyperglycemic effect
-helps maintain blood pressure and helps body resist the effects of stress
deficiency of insulin results in
diabetes mellitus
majority of each testis is composed of
coiled seminiferous tubules
glucagon opposed what
insulin
increases blood glucose levels by acting on the liver to convert glycogen to glucose
what is the overall effect of insulin
to lower blood glucose levels
true or false the pancreas has both endocrine and exocrine functions
true
the adrenal medulla produces what?
epinephrine and norepinephrine
what is addisons disease
deficiency of aldosterone
results in dehydration, sodium depletion, and potassium excess