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Endocrine system
Initiates responses slowly, Long duration responses, Acts via hormones released into the blood, Acts at diffuse locations targets can be anywhere blood reaches, Hormones act over long distances.
Nervous system
Initiates responses rapidly, Short duration responses, Acts via action potentials and neurotransmitters, Acts at specific locations determined by axon pathways, Neurotransmitters act over very short distances.
Homeostasis
Maintains and regulates internal balance of water and nutrient levels, metabolism, immune response, growth and development, and reproduction.
Endocrine glands
Ductless glands that release secretions (hormones) into surrounding body fluids (interstitial fluid, lymph system, and blood stream).
Hormones
Chemical signals released by endocrine cells that act on target cells through hormone receptors, influencing various physiological processes.
Hormone receptors
Expressed by target cells, they act via intracellular second-messenger pathways to transmit the hormonal signal and initiate a cellular response.
Second-messenger pathways
Amplify the initial hormonal signal by multiplying the response at each stage of subsequent activation and control, allowing for temporal, spatial, quantitative, and qualitative regulation.
Adrenaline
Stress hormone and neurotransmitter acting on various organ systems.
Serotonin
Hormone and neurotransmitter that affects the cardiovascular system and is often referred to as the "happiness" transmitter.
Melatonin
Hormone and neurotransmitter that helps regulate our circadian "inner" clock.
Growth hormone
Controls growth and development.
Antidiuretic hormone (ADH)
Regulates water reabsorption by the kidneys.
Insulin
Lowers blood sugar level.
Glucagon
Increases blood sugar level.
Steroid hormones
Lipid-soluble hormones synthesized from cholesterol that can enter the cell and act on intracellular receptors to directly activate genes.
Negative feedback
Regulatory mechanism that brings an internal condition or signal back to homeostasis by stimulating a physiological response.
Humoral stimuli
Change of ions or nutrients in the body fluids detected by receptors of endocrine cells, triggering the release of appropriate hormones.
Neural stimuli
Stimulation of endocrine cells by neurons, such as the release of adrenaline in response to stress.
Hormonal stimuli
Endocrine cells responding to hormones released by other endocrine cells.
Cell-specific response
Binding of a hormone triggers a cellular response that is specific to the target cell, influenced by hormone concentration, density of receptors, and receptor affinity.
Permissiveness
One hormone requires the presence of another hormone to exert its full effect, allowing for fine-scale temporal and spatial control.
Synergism
More than one hormone produces the same effect in a target cell, amplifying the overall effect.
Antagonism
Different hormones oppose each other's actions, resulting in a response from the target cell that depends on the hormone-hormone interaction.