UAMS P2 - Summative Exam 1 Practice

Which of the following is an example of Enteric Coating? (CEUTICS 1)

A) MCC

B) Cellulose Acetate Phthalate

C) HPMC

D) Sucrose

Cellulose Acetate Phthalate

Which amendment required manufactures to prove a Drug is Safe and Effective? (CEUTICS 1)

A) Pure Food and Drug Act

B) Durham-Humphrey

C) Drug Quality and Security

D) Kefauver-Harris

Kefauver-Harris

Which Ocular formulation has greater Bioavailability? (CEUTICS 1)

A) Ointments

B) Drops

C) Suspensions

D) Emulsions

Ointments

Ocular formulations should be (CEUTICS 1)

A) Hypotonic

B) Isotonic

C) Hypertonic

D) Mesotonic

Isotonic

Which Dispersion system would likely pass through Semipermeable membrane but is invisible in a Electron Microscope? (CEUTICS 1)

A) Molecular Dispersion

B) Colloidal Dispersion

C) Dipyramidal Dispersion

D) Coarse Dispersion

Molecular Dispersion

T/F: Transdermal Drug Delivery Systems target is the skin where as topical drugs target the systemic effect (CEUTICS 1)

False - Other way around (TDDS = Systemic, Topical = Skin)

1 multiple choice option

Which agent leads to near fatal death if administered Intrathecally? (CEUTICS 1)

A) Baclofen

B) Etoposide

C) Clonidine

D) Vincristine

Vincristine

Which of the following is another name for Vit. B2? (CEUTICS 1)

A) Pyridoxine

B) Riboflavin

C) Thiamine

D) Cyancobalamin

Riboflavin

Which of the following is another name for Vit. D3? (CEUTICS 1)

A) Cholecalciferol

B) Ascorbic Acid

C) Ergocalciferol

D) Tocopherol

Cholecalciferol

What Supplement is high recommended for pregnant patients? (CEUTICS 1)

A) Vit D

B) Ferrous Sulfate

C) Folic Acid

D) Zinc

Folic Acid

How many drops are in 1 mL? (Calculations)

A) 10

B) 5

C) 20

D) 30

20

1000mcg = __________ mg (Calculations)

A) 0.1

B) 0.01

C) 1

D) 10

1

1 in = ___________ cm (Calculations)

A) 3.52

B) 1.43

C) 1.98

D) 2.54

2.54

Which Opioid is the MOST potent?

A) Codeine

B) Fentanyl

C) Oxymorphone

D) Hydrocodone

Fentanyl

In terms of SIG codes, AU means (Calculations)

A) Left eye

B) Right ear

C) Both ears

D) Right eye

Both ears

In terms of SIG codes, OS means (Calculations)

A) Left eye

B) Right ear

C) Both eyes

D) Left ear

Left eye

In terms of SIG codes, AC means (Calculations)

A) Before Meals

B) With Meals

C) After Meals

D) Without Meals

Before Meals

In terms of SIG codes, PC means (Calculations)

A) Before Meals

B) With Meals

C) After Meals

D) Without Meals

After Meals

Which of the following would mean "Recalls that could lead to injury or death"? (Drug Info)

A) Class 4 Recall

B) Class 2 Recall

C) Class 3 Recall

D) Class 1 Recall

Class 1 Recall

Which of the following is teratogenic? (Drug Info)

A) Captopril

B) Metformin

C) Metoprolol Succinate

D) Amlodipine

Captopril

Methotrexate should be dosed: (Drug Info)

A) Once daily

B) Once monthly

C) Twice weekly

D) Once weekly

Once weekly

Which of the following contains both empagliflozin and metformin? (Drug Info)

A) Invokamet

B) Xigduo

C) Steglatro

D) Synjardy

Synjardy

Which of the following is NOT a contraindication of GLP1s? (Drug Info)

A) Cardiovascular Disease

B) Thyroid Cancer

C) Pancreatitis

D) Endocrine neoplasia

Cardiovascular Disease

Which Insulin would NOT require a prescription? (Drug Info)

A) Novolog 70/30

B) Admelog

B) Humulin N

C) Humulin R

Admelog

Which insulin cannot be given as Insulin Pump? (Drug Info)

A) Apidra

B) Lyumjev

C) Fiasp

D) Admelog

Fiasp

Which medication can be used for treatment of deficiency of hair (hypotrichosis)? (Drug Info)

A) Lumigan

B) Travoprost

C) Latisse

D) Azopt

Latisse

Which of the following would be used to treat Osteoporosis? (Drug Info)

A) ibandronate

B) budesonide

C) alirocumab

D) Zaditor

ibandronate

Which of the following should NOT be dosed once daily? (Drug Info)

A) metoprolol succinate

B) carvedilol

C) Lopressor

D) Saxenda

Lopressor

Which statin does NOT have to be taken at night? (Drug Info)

A) lovastatin

B) Crestor

C) simvastatin

D) Lescol

Crestor

Which of the following NOT part of the Triple Aim of Health Care Reform? (US. Healthcare)

A) Improve population health

B) Enhance patient experience of care

C) Expand the scope of medical services offered

D) Reduce or control cost of care

Expand the scope of medical services offered

Which of the following providers CAN prescribe Medications? (US. Healthcare)

A) Occupation Therapist

B) Respiratory Therapist

C) Doctor of Chiropractic

D) Physician Assistance

Physician Assistance

Which Arkansas state Act required PBMs to reimburse pharmacies greater than or equal to the medication acquisition cost? (US. Healthcare)

A) Arkansas Reimbursement Protection Policy

B) Arkansas Equal Sale Act

C) Arkansas Act 900

D) Arkansas PBM Transparency Act

Arkansas Act 900

The Affordable Care Act addressed 3 issues. Which of the following is NOT one of those issues? (US. Healthcare)

A) Increasing Provider Reimbursement Rates

B) Expanding Coverage

C) Controlling Health Care costs

D) Improving Health Care Delivery Systems

Increasing Provider Reimbursement Rates

Pharmacies are typically reimbursed ________________ and pharmacists are paid ____________________. (US. Healthcare)

A) Per diem; Salary

B) Capitation; Per diem

C) Fee-For-Service; Salary

D) Fee-For-Service; Per diem

Fee-For-Service; Salary

Which of the following can prescribe Control medications without needing approval from a physician? (US. Healthcare)

A) DDS

B) APRN

C) PA

D) RT

DDS

Which of the following is NOT a factor of Healthcare Quality? (US. Healthcare)

A) Access

B) Cost

C) Equity

D) Efficiency

Cost

Which form of emulsion instability is Irreversible? (Ceutics 2)

A) Creaming

B) Flocculation

C) Caking

D) Breaking

Breaking

An HLB of 3-6 indications the emulsion is: (Ceutics 2)

A) W/O

B) O/W

W/O

An HLB of 8-18 indications the emulsion is: (Ceutics 2)

A) W/O

B) O/W

O/W

Which of the following ingredients is commonly used for Osmotic Pumps to form a semipermeable membrane? (Ceutics 2)

A) Cellulose Acetate

B) Beeswax

C) HPMC

D) Ethylcellulose

Cellulose Acetate

Use of Aspirin in children can lead to (PCol 1)

A) Acute Rheumatic Fever

B) Guillain-Barre Syndrome

C) Stevens-Johnson Syndrome

D) Reye's Syndrome

Reye's Syndrome

Which of the following is a Natural Thyroid? (PCol 1)

A) Liothyronine

B) Levothyroxine

C) Armour Thyroid

D) Liotrix

Armour Thyroid

Which Selective Estrogen Receptor Modulator has the HIGHEST risk of causing DVT? (PCol 1)

A) Tamoxifen

B) Raloxifene

D) Toremifene

C) Clomiphene

Raloxifene

Which of the following agents can cause osteonecrosis of the jaw? (PCol 1)

A) Cinacalcet

B) Denosumab

C) Etidronate

D) Teriparatide

Denosumab

Which of the following is a key indicator on the difference between Opioid Withdrawal vs Opioid Addiction? (PCol 1)

A) Piloerection

B) Mydriasis

C) Miosis

D) Anxiety

Miosis

Which patient population is at highest risk of developing respiratory depression when taking Codeine (CYP2D6 Metabolism)? (PCol 1)

A) Poor Metabolizers

B) Ultra-Rapid Metabolizers

C) Kids < 12

D) Elderly

Ultra-Rapid Metabolizers

Which of the following would recommended for an Opioid-Naive Asthma patient needing an opioid? (PCol 1)

A) Morphine

B) Meperidine

C) Fentanyl

D) Methadone

Methadone

Which insomnia treatments are the only ones approved for onset and maintenance? (PCol 1)

A) Ramelteon and Zaleplon

B) Eszopiclone and Zolpidem

C) Ramelteon and Eszopiclone

D) Zaleplon and Zolpidem

Eszopiclone and Zolpidem

Which of the following is first-line treatment for Parkinson's? (PCol 1)

A) Amantadine

B) Selegiline

C) Carbidopa/Levodopa

D) Cabergoline

Carbidopa/Levodopa

Which agent should NOT be used for Chronic Insomnia? (PCol 1)

A) Zaleplon

B) Diphenhydramine

C) Lunesta

D) Silenor

Diphenhydramine

Patient's switching from SSRI to MAOI should wait at least ___________ before taking: (PCol 1)

A) 1 week

B) 10 days

C) 4 weeks

D) 3 months

4 weeks

Which Atypical Antidepressant is NOT contraindicated with Selegiline (MAOI)? (PCol 1)

A) Bupropion

B) Mirtazapine

C) Trazodone

D) Esketamine

Esketamine

Which agent can be used in kids with Tourette's Syndrome? (POPP)

A) Rexulti

B) Seroquel

C) risperidone

D) aripiprazole

aripiprazole

Which adverse effect applies to ALL antipsychotics? (POPP)

A) Weight gain

B) Tardive dyskinesia

C) Hyperlipidemia

D) Syncope

Tardive dyskinesia

Which agent would be used in BPH to decrease prostate size? (POPP)

A) Proscar

B) Flomax

C) alfuzosin

D) doxazosin

Proscar

Patient comes to your pharmacy to pick up her birth control. She is an avid smoker. What could happen if she took a birth control product that contained Estrogen?

A) Dyspepsia

B) Increased DVT Risk

C) Hypogonadism

D) Arrhythmias

Increased DVT Risk

Patient comes to your pharmacy to pick up her birth control. She is an avid smoker. Which agent would be best for her?

A) Sprintec

B) Beyaz

C) Amethyst

D) Camila

Camila

Tamiflu for flu treatment should be given: (POPP)

A) TID for 5 days

B) BID for 10 days

C) BID for 5 days

D) QD for 10 days

BID for 5 days

Which of the following is a HAART medication for HIV treatment? (POPP)

A) Genvoya

B) Norvir

C) Viread

D) Truvada

Genvoya

Which of the following can be used as PrEP therapy for HIV Prophylaxis? (POPP)

A) Fuzeon

B) Norvir

C) Truvada

D) Selzentry

Truvada

Which of the following USP chapters refers to Sterile Preparation? (POPP)

A) USP 800

B) USP 797

C) USP 825

D) USP 795

USP 797

Which of the following USP chapters refers to Hazardous Drugs? (POPP)

A) USP 800

B) USP 797

C) USP 825

D) USP 795

USP 800

Which of the following USP chapters refers to Non-Sterile Compounding? (POPP)

A) USP 800

B) USP 797

C) USP 825

D) USP 795

USP 795

Which of the following USP chapters refers to Radiopharmaceuticals? (POPP)

A) USP 800

B) USP 797

C) USP 825

D) USP 795

USP 825

PEC/Hood located within the Buffer Room should be rated: (POPP)

A) ISO 3

B) ISO 5

C) ISO 7

D) ISO 8

ISO 5

The Buffer Room should be rated: (POPP)

A) ISO 3

B) ISO 5

C) ISO 7

D) ISO 8

ISO 7

The Ante Room should be rated: (POPP)

A) ISO 3

B) ISO 5

C) ISO 7

D) ISO 8

ISO 8

Beyond Use Date for Immediate-Use CSPs: (POPP)

A) 12 hours

B) 2 hours

C) 4 hours

D) 6 hours

4 hours

Beyond Use Date for CSPs made within a PEC in a fully compliant clean room using only Sterile products: (POPP)

A) 4 days

B) 28 days

C) 30 days

D) 10 days

10 days

Multi-Dose vials beyond use date after puncture (unless noted otherwise by manufacturer): (POPP)

A) 28 days

B) 30 days

C) 14 days

D) 60 days

28 days

Which USP chapter is NOT enforceable and set as informational only? (POPP)

A) USP 795

B) USP 800

C) USP 989

D) USP 1001

USP 1001

Which List identifies Hazardous Drugs? (POPP)

A) FDA Orange Book

B) NIOSH

C) FDA Purple Book

D) ISMP High-Alert Medication List

NIOSH

Which of the following statements is false regarding USP 800? (POPP)

A) Requires the use of 2 pairs of shoe covers when compounding HDs

B) Requires wearing 2 pairs of chemotherapy gloves for both Sterile and Non-sterile HD compounding

C) Changing of gloves are should be done every 30mins or immediately after compounding HDs

D) Surgical Masks rated N95 can be used when compounding HDs

Surgical Masks rated N95 can be used when compounding HDs

Which resource should be used to determine IV Compatibility? (POPP)

A) Trissel's

B) FDA Green Book

C) Compatibility Wall Charts

D) FDA Purple Book

Trissel's

Which IV therapy ingredient should be avoided in infants and young children? (POPP)

A) Benzyl Alcohol and Propylene Glycol

B) Dextrose and Propylene Glycol

C) NaCl and Dextrose

D) KCl and Benzyl Alcohol

Benzyl Alcohol and Propylene Glycol

Which agent should NEVER be given via IV push? (POPP)

A) MgSO4

B) KCl

C) Calcium Gluconate

D) NaCl

KCl

Rapid infusion of Vancomycin can lead to: (PK)

A) Red man syndrome

B) Cardiovascular Comorbidities

C) Flushing

D) Stevens-Johnson Syndrome

Red man syndrome

Vancomycin 1g should be infused over: (PK)

A) 4hrs

B) 30mins

C) 1hr

D) 2hrs

1hr

Vancomycin 1.5g should be infused over: (PK)

A) 4hrs

B) 30mins

C) 1hr

D) 2hrs

2hrs

T/F: Vancomycin can be given as IV and IM (PK)

False - No IM

1 multiple choice option

Which First gen Antihistamine is MOST likely to have potent Anti-cholinergic effects? (MedChem)

A) loratadine

D) dimenhydrinate

C) Benadryl

D) promethazine

promethazine

Which 1st Gen Antihistamine is also Cardiotoxic? (MedChem)

A) meclizine

B) hydroxyzine

C) cyclizine

D) diphenhydramine

hydroxyzine

Which 1st Gen Antihistamine can lead to dementia? (MedChem)

A) chlorpheniramine

B) ketotifen

C) doxepin

D) diphenhydramine

diphenhydramine

Which 1st Gen Antihistamine is preferred in 1st trimester of pregnancy? (MedChem)

A) chlorpheniramine

B) ketotifen

C) doxepin

D) diphenhydramine

chlorpheniramine

Which Antihistamine agent would MOST LIKELY be LEAST sedating? (MedChem)

A) hydroxyzine

B) promethazine

C) cetirizine

D) doxylamine

cetirizine

Which Antihistamine is NOT recommended for elderly? (MedChem)

A) diphenhydramine

B) loratadine

C) fexofenadine

D) cetirizine

diphenhydramine

Patients with sulfa allergies should avoid the following agents EXCEPT: (MedChem)

A) Bactrim

B) HCTZ

C) Ethacrynic Acid

D) Bumetanide

Ethacrynic Acid

A patient is experiencing Hyponatremia. Which agent is likely the cause? (MedChem)

A) eplerenone

B) spironolactone

C) furosemide

D) chlorthalidone

chlorthalidone

Which Supplement could be used for Benzo withdrawal? (MedChem)

A) Ginko

B) Valerian Root

C) Stevia

D) Turmeric

Valerian Root

Which Supplement could be used for osteoarthritis? (MedChem)

A) Ginko

B) Valerian Root

C) Stevia

D) Turmeric

Turmeric

Which Supplement could be used for dementia prevention? (MedChem)

A) Ginko

B) Valerian Root

C) Stevia

D) Turmeric

Ginko

Which Supplement could be used for HTN? (MedChem)

A) Ginko

B) Valerian Root

C) Stevia

D) Turmeric

Stevia

Which Insurance group is likely to have More Control with Lower Costs? (US Healthcare)

A) PPO

B) HMO

C) POS

D) HDHP

HMO

Injection of Insulin is most effective and fastest when administered into the:

A) arms

B) abdomen

C) thighs

D) butt

abdomen

Which of the following statements is true? (Drug Info)

A) Rotating sites for each injection avoids lipohypertrophy

B) Humulin R U-500 is available without a prescription

C) Tresiba is a short-acting insulin

D) All biosimilars of insulin are interchangeable

Rotating sites for each injection avoids lipohypertrophy

Which application is required before Human clinical trials can begin? (Drug Info)

A) NDA

B) IND

C) BLA

D) ANDA

IND

Which resource should be used to report Adverse Events with medications that were not expected? (Drug Info)

A) MedWatch

B) REMS

C) FAERS

D) ISMP MERP

MedWatch

Which act stimulated development of drugs for rare diseases and involves an incentive program? (Drug Info)

A) Emergent Medications Act

B) Drug and Safety Act

C) Therapeutic Innovation Act

D) Orphan Drug Act

Orphan Drug Act

Black Box warning for Metformin: (Drug Info)

A) Hypoglycemia

B) Sudden death

C) Lactic Acidosis

D) Severe Diarrhea

Lactic Acidosis

Which agent would be used for Homozygous Familial Hypercholesterolemia? (Drug Info)

A) Juxtapid

B) Nexletol

C) Vascepa

D) Lopid

Juxtapid