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Functions of the nervous system
sensory input, integration, and motor output
Sensory input
To monitor changes occurring inside and
outside the body (stimuli)
Integration
To process and interpret sensory input and
decide if action is needed
This happens in the brain primarily
motor output
A response to integrated stimuli
The response activates muscles or glands
Central Nervous System (CNS)
Brain
Spinal cord
Peripheral Nervous System (PNS)
Spinal nerves
Cranial nerves
PNS: Sensory (afferent) division
Nerve fibers that carry information to the
central nervous system
Nerve fiber approach the CNS
PNS: Motor (efferent) division
Nerve fibers that carry impulses away from the
central nervous system
Nerve fibers exit the CNS
Subdivisions of the Motor (efferent) division
Somatic Nervous system (voluntary), Autonomic Nervous system (involuntary)
Somatic Nervous system
voluntary, skeletal muscles
Autonomic Nervous system
involuntary, cardiac and smooth muscle (Sympathetic nervous system = fight or flight, Parasympathetic nervous system = rest and digest)
Support cells in the CNS are grouped together as
Neuroglia (glial cells), their function is to support, insulate, and protect
Types of neuroglia (glial cells):
Astrocytes
Microglia
Ependymal cells
Oligodendrites - CNS only
Schwann cells - PNS only
Types of neuroglia (glial cells): Astrocytes
Abundant, star-shaped cells
Brace neurons
Form barrier between capillaries and neurons
Control the chemical environment of
the brain
Mop up leading potassium ions and
recapture neurotransmittors
Types of neuroglia (glial cells): Microglia
Spiderlike phagocytes
Dispose of debris like dead nerve cells and
bacteria
Types of neuroglia (glial cells): Ependymal cells
Line cavities of the brain and spinal cord
Circulate cerebrospinal fluid using beating
cilia
Types of neuroglia (glial cells): Oligodendrocytes
Wrap around nerve fibers in the central
nervous system - CNS
Produce myelin sheaths
Types of neuroglia (glial cells): Satellite cells
Protect neuron cell bodies by cushioning the
cells
Types of neuroglia (glial cells): Schwann cells
Form myelin sheath in the peripheral nervous
system
Neurons = nerve cells
Cells specialized to transmit messages
Major regions:
Cell body—nucleus and metabolic center
of the cell
Dendrites
conduct impulses toward the cell
body
Axons
conduct impulses away from the cell
body
Axonal terminals
are separated from the next
neuron by a gap
Axonal terminals: Synaptic cleft
gap between adjacent neurons
Axonal terminals: Synapse
junction between nerves
Neurotransmitters
chemicals that transmit an
impulse across a synapse to another cell, are found in tiny vesicles
(or bubbles of cell membrane) in the axon
terminal,
neurotransmitter ex
Dopamine
Adrenaline
Endorphins
Myelin sheath
whitish, fatty material covering axons, produced by Schwann Cells
Nuclei
clusters of cell bodies within the white
matter of the central nervous system
Ganglia
collections of cell bodies outside the
central nervous system in the PNS
Tracts
are bundles of nerve fibers running
through the CNS
Nerves
are bundles of nerve fibers running
through the PNS
White matter
consists of dense collections of
myelinated fibers (tracts)
Gray matter
mostly unmyelinated fibers and cell
bodies
Sensory (afferent) neurons
Carry impulses from the sensory receptors to
the CNS
Cutaneous sense organs
Pain receptors – perceive pain
Meissner’s corpusles – perceives light
touch
Pacinian corpusles – perceives deep
pressure
Proprioceptors—detect stretch or tension
Motor (efferent) neurons
Carry impulses from the central nervous
system to viscera, muscles, or glands
Interneurons (association neurons)
Found in neural pathways in the central
nervous system
Connect sensory and motor neurons
Multipolar neurons
many extensions from the
cell body – most common type, they are all motor
neurons and association neurons
Bipolar neurons
one axon and one dendrite –
these are rare, found only in the eye and nose
Unipolar neurons
have a short single process
leaving the cell body – these are the sensory
neurons in the PNS ganglia
Irritability
Ability to respond to stimuli
Conductivity
Ability to transmit an impulse
Resting neuron
The plasma membrane is polarized-
Fewer positive ions are inside the cell than
outside the cell
Depolarization
A stimulus depolarizes the neurons
membrane
membrane allows sodium (Na+)
to flow inside the membrane
Action potential
If the action potential (nerve impulse) starts, it
is propagated over the entire axon
Impulses travel faster when fibers have a
myelin sheath
Repolarization
Potassium ions rush out of the neuron after
sodium ions rush in, which repolarizes the
membrane
The sodium-potassium pump, using ATP,
restores the original configuration
how: Impulses are able to cross the synapse to another
nerve
Neurotransmitter is released from a nerves
axon terminal.
The dendrite of the next neuron has receptors
that are stimulated by the neurotransmitter
An action potential is started in the adjacent
neuron.
threshold
the minimum level of stimulus
that is required to cause an impulse in a neuron. (minimum = -70 mV.)
Reflex arc
direct route from a sensory neuron, to
an interneuron, to an effector
The reflex arc has 5 parts:
1. Sensory receptor
2. Sensory (afferent) neuron
3. Integration center
4. Motor (efferent) neuron
5. Effector organ