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Somatic sensory/afferent
Conscious information from skin and muscles
Visceral sensory/afferent
Subconscious information from body organs
Somatic motor/efferent
Conscious commands (skeletal muscle)
Autonomic motor/efferent
Subconscious commands (smooth and cardiac muscle)
Nervous tissue
Poor repair, highly cellular, high metabolism (needs lots of glucose and oxygen)
Neurons
Also called nerve cells or neurocytes, functional unit of the nervous system, long and thin, human body contains 10^12 neurons
Central nervous system
Brain and spinal cord, integrates and controls
Peripheral nervous system
Cranial nerves and spinal nerves, communication lines between the CNS and the rest of the body
Sensory/afferent division
Conducts impulses drom receptors to the CNS
Motor/efferent division
Conducts impulses from the CNS to muscle and glands
Somatic nervous system
Conducts impulses from the CNS to the skeletal muscle
Autonomic nervous system
Conducts impulses from the CNS to cardiac muscles smooth muscles and glands
Multipolar
Many processes extend from the cell body, all are dendrites except for one axon
Bipolar
Two processes extend from the cell body. One is a fused dendrite the other is an axon
Unipolar
One process extends from the cell body and forms central and peripheral processes, which togethr comprise an axon
Nucleus
A collection if neuron cell bodies in the CNS
Ganglion
A collection if neuron cell bosies in the PNS
Tract
A bundle of axons in the CNS
Nerve
A bundle of axons in the PNS
Glial cells
Cells in nervous tissue that support neurons
Resting state
All gated Na+ and K+ channels are closed
Depolarization
Na+ channels are open. Allowing Na+ to enter
Repolarization
Na+ channels are inactivating K* channels open, allowing K+ to exit
EPSP
A local DEPOLARIZATION of the postsynaptic membrane
IPSP
A hyperpolarization of the postsynaptic membrane
No summation
A slowly firing presynaptic neurom that causes EPSPs that are far apart in time
Temporal summation
A rapidly firing presynaptic neuron causes EPSPs that are close in time
Spatial summation
More than one presynaptic neuron fires at the same time, EPSPs are generated at different locations on the neuron
Cell body
Contains the nucleus and most organelles
Dendrites
Short, branches, many, close to cell body
Axon
Single long projection, arises from axon hillock
Myelin sheath
White, fatty, segmented layer on the axon
Axon terminal
Distal tip, holds and releases neurotransmitter
Cell bodies
Gray
Myelinated axon
White
Astrocytes
CNS, most abunday and versatile support cells
Microglia
CNS, protective cells that destroys foreign microorganism
Ependymal cells
CNS, lines the edges of ventricles, produces CSF
Oligodendrocytes
CNS, wraps around neurons to form myelin sheath
Satelite cells
PNS, attaches to neuron cell bodies
Schwann cells
PNS, wraps around axons to form the myelin sheath
Voltage
Measures potential energy, Volts V
Current/flow
Measures the flow of electrocal charge from 1 point to another. Amperes I
Charge
Measures total number of charged particles by a current. Coulumbs Q
Resistance
Measures how difficult things are. Ohms R
Conductance
Measures how easy things are. Siemans
Ohms law
Voltage= current x resistance. If a current forms the voltage will change
Ligand-gated channels
Channel opens when a particular chemical binds to it. Low conductance
Voltage-gated channels
Channel opens due to a change in local charge distribution (high conductance)
Mechanicaly-gated channels
Channel opens in response to a physical stimulus
Leak channel
Channel always open. Allows K+ to pass sometimes. Low conductance
Ion direction
Based on the electrochemical gradient
Relative refractory period
Most Na+ channels are still open and repolarization is occuring
Absolute refractory period
Begins with opening of the Na+ channels and ends when the Na+ channels reset
Multiple sclerosis
Demyleninating disorder, causes hardened patches in the brain and spinal cord
Saltatory conduction
Transmission of an AP along a mylinated fiber in which the AP leaps from gap to gap
Conduction velocity
100 m/s
Group A fibers
Large diameter axon, heavily myelinated, conducts at 300 MPH, somatic pathway
Group B fibers
Small diamter axon, light mylinated, cpnduct at 30 MPH, autonomic pathways
Group C fibers
Smallest diameter axon, not mylinated, conducts at 2MPH, used by autonomic
Electrical synapses
Channels that are similar to gap junction
Chemical synapses
Uses a neurotransmitter, 1 cell is always infront of eachother
Presynaptic cell
The neuron before synapses, when the axon terminal communicates and sends the signals
Postsynaptic cell
Neurons after synapse, when the dendrites connect and recieve the signal
Graded potential
Small, local changes in voltage. Uses ligand-gated channels
EPSP
A depolarizing grading potential
IPSP
A hyperpolarizing grading potential
Axodendritic synapses
Connects to postsynaptic dendrites
Axosomatic synapses
Connects to postsynaptic cell body
Axoaxonic synapses
Connects to postsynaptic axon hillock
Acetylcholine
First neurotransmitter, used in neurotransmitter junction, can alter organ function
Norepinephrine
Alters organ function, in the CNS it is a pleasure neurotransmitter
Dopamine
In the CNS it is a pleasure neurotransmitter, excessive signaling causes schizophrenia
Serotonin
Regulates mood, release is linked to eating. Ecstacy
GABA
Main inhibitory neurotransmitter, opens ligand-gated Cl- channel
Glycine
Main inhibitory neurotransmitter of the spinal cord
Glutamate
Main excitory transmitter
Endorphins
Natural inhibitors of pain, released under stressful conditions
Kinins
Transmit pain signals released from damaged dells
Cerebral cortex
Gray, Superfical later of gray matter, neuron cell bodies contain many nuclei
Cerebral white matter
White, deep layer of white matter, myelinated axons, contains many tracts
Basal nuclei
Gray, islands of gray matter within the white. Deep isolated gray matter
Ventricles
Hollow, filled eith CSF
Lateral ventricles
Largest a pair c-shaped deep to cerebral hemisphere
Third ventricle
Thin channel deep to diencephalon
Fourth ventricle
Diamond-shaped deep to brain stem
Folding
Increases more surface area meaning more neurons meaning higher intelligence
Gyrus/gyri
An elevated ridge if brain tissue
Sulcus/sulci
A shallow grooce in brain tissue
central sulcus
Seperates frontal and parietal lobes
Lateral sulcus
Outlines the top of temporal lobes
Parieto-occipito sulcus
Seperates parietal and occipital sulcus
Left brain
Math, logic, analytic and language
Right brain
Creativity, artistic, visual, nonverbal, communication
Homunculus
oversized body parts = sensitive to touch
Epilepsy
Abnormal and excessive electrical signals generated in the brain
Petit mal
Blank facial expressions, facial muscle tics
Grand mal
Body convulsions, loss of consciousness
Premotor cortex
Used for coordinated movements of several muscle groups
Frontal eye field
Voluntarily aims the eye