bio 9/13 - levels of protein structures

4 levels of protein structure

primary

secondary

tertiary

quaternary

Primary structure

sequence of amino acids from the amino end to the carboxyl end

Secondary structure

H bonding between peptide bonds and adjacent or nearly adjacent amino acids. DOES not involved the R groups

2 types of structures in secondary proteins

alpha helix

beta-pleated sheet

spiral-shaped

secondary alpha helix

Resulting from interaction between R groups or between R groups at a distance and backbone

tertiary structure

level of structure that has hydrophobic interactions or disulfide bonds

tertiary

Tertiary structure is stabilized by what kinds of bonds?

h bonds

ionic

hydrophobic

disulfide

what is studied by denaturing protein and watching it renature

protein folding in secondary and tertiary structures

quaternary structure

results from interactions between multiple polypeptide chains - held together by ionic, hydrogen, SS and hydrophobic interactions/bonds

bonds in quaternary structure

h bonds

disulfide bonds

hydrophobic interactions

ionic

N terminus

the end of a polypeptide or protein that has an amino group

C-terminus

the end of a polypeptide or protein that has a carboxyl group