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Infection
Invasion of body tissues by microorganisms that proliferate and grow, causing infection
Infection Sources
Endogenous, Exogenous
Endogenous
Within patient (from normal flora)- Healthy microorganisms
Ex) candida – yeast infection, thrush
Exogenous
From the environment / transmitted from person to person
Infection Sites
Local, Systemic
Local Infection Sites
Specific/confined area
Ex) UTI – confined to the bladder/urinary region/inflammation
Systemic Infection Sites
Organisms spread to multiple systems
Ex) bacteremia, sepsis, MODS (multiple organ dysfunctional syndrome)
Nosocomial/Healthcare Acquired Infection (HAI)
Caught in hospitals/healthcare facilities
Iatrogenic
Physician induced, therapeutic or diagnostic procedures (can cause infection)
Ex) CAUTI, CLABSI, VAP
Opportunistic
Disruption of body defenses, and then normal microorganisms that are present in the body proliferate
Ex) antibiotics causing normal flora disruption and causing a yeast infection
Defenses Against Infection
Nonspecific, Specific
Nonspecific
Barriers- First line of defenses
Anatomic (ex. Skin, mucous membranes) – Dust Particles
Physiologic (Ex. Phagocytosis – engulfing foreign pathogen, saliva, sweat)
Inflammatory Response (LAS)
GAS – how body defends itself
»By confining the injury to the smallest part of the body as possible!
Specific - GAS
Antibody-mediated (humoral) Immunity
Active immunity (immunization)
Natural vs. artificial immunity (nurses are exposed to many organisms, hospital workers are more immune to some diseases because of this – natural) – develops only through deliberate actions of exposure
Cell-Mediated (Cellular) Immunity
Killer T cells
Lymphatic system
Older Adults & Infections
All body systems decrease in function in older ages including the immune system
Contributing Factors in Infection
Increasing Risk: Chemical, Developmental, Iatrogenic, Physical, Physiological, Psycho-socio-cultural
Microbiological etiologic agents: Bacteria, fungus, virus, C-Diff, E. Coli, MRSA/VRE.
Chemical (Increasing Risk of Infection)
Ex) anesthesia – slows BMR (Basal metabolic rate)
Ex) harsh soap – can decrease essential oils in the skin causing skin tears
Ex) antimicrobials (antibiotics) – build immunity among microorganisms because we don’t complete treatment (antibiotics should be the last mode of intervention)
Developmental (Increasing Risk of Infection)
The very old and very young are more suscep
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Physical (Increasing Risk of Infection)
Radiation
Hot water- can cause burns and damage skin
Sheering forces- pulling patients up in bed can cause skin tears
Physiological (Increasing Risk of Infection)
Those immunocompromised individuals – disease-causing
Those that are malnourished, pregnant, neutropenic precautions (decrease in WBC count – seen often in oncology patients)
Interference of urine flow – stasis – urine isn’t being excreted = UTI
Changes in G.I.
Psycho-socio-cultural (Increasing Risk of Infection)
Stress, anxiety, other cultural factors
Bacteria, fungi, viruses
Pathogenic in nature
C-Diff (NO GEL, wash hands)
Spore-forming organism, hard to get rid of, chief cause = diarrhea, yellow/watery stool, must get stool culture to test
E. Coli
Normal flora found in G.I. tract, seen 40 hours after birth in our stomachs, when it gets into other systems outside the G.I. tract is when it causes infection (Anus: always wipe front to back)
MRSA/VRE
Methicillin-Resistant Staphylococcus Aureus & Vancomycin-Resistant Enterococci
Found on the skin- make sure not to spread it
Clinical Manifestations of Infections
Inflammation (LAS)- Abbreviation (HELPE or HELPS)
Exudate (drainage)- Characteristic of infection, 4 types
Inflammation (LAS) - (HELPE/HELPS)
Heat
Erythema
Loss of function
Pain
Edema aka Swelling
Exudate (drainage)
Serous, purulent (pus), sanguineous (blood), serosanguineous (serous and bloody)
Serous
Clear/yellow (drainage from wounds)
This occurs when in the healing process!!!
Occurs in abrasions (other breaks in the skin that aren’t as deep)
Purulent (pus)
Contains bacteria – makes it cloudy
Can range in color – depending on what organism is in the exudate
Sanguineous (blood)
Would see this kind of exudate when there is a tear in the tissue
Serosanguineous (serous and bloody)
Pinkish in nature
Would see this kind of exudate in the healing process (Looks like cranberry juice)
Systemic Manifestations
Fever
Leukocytosis
Malaise
Anorexia
Nausea, vomiting
Organism is in the G.I. tract – body wants to expel it! (“stomach virus”)
Headache
Lymphadenopathy
Other manifestations related to specific infection
Modes of Transmission
3 modes:
Direct transmission, Airborne Transmission, Indirect Transmission
Direct Transmission
If host Is susceptible, it can be transmitted through touch.
Touching- Contact— Gloves and gown
» MRSA, C.Diff (contact-plus)
Droplet - Respiratory infection (Mucus membrane)
» Through cough or sneeze from one to another (within 3 ft)
Airborne Transmission
Very small particles (N-95)
Inhalation of droplet/dust particles
Can remain suspended in the air for longer periods (cough and sneeze)
Ex; tb, rsv, legions diseases
Indirect Transmission
Vehicle-borne
Soiled linens, soiled furniture
Vector-borne- animals or insects
Ex; animal/insect transport or transmit disease
Live host- either bitten, scratched (ticks, mosquitos)
Asepsis
Absence of infection. Try to reduce as many microorganisms in the patient’s environment as possible.
Contaminated
Contain disease producing organisms
Historical Perspective
Germ Theory:
Asepsis types
Medical & Surgical
Medical
Decrease the amount of microorganisms by eliminating gross contamination
Confine organisms to the smallest area possible to prevent the spread
“Clean” technique
Surgical
Specific process to keep area free of microorganisms
IV, Foley, OR, Dressing, Trac care
“Sterile” technique
Principles of Surgical Asepsis
All objects in a sterile field must be sterile
Sterile objects become unsterile when touched by unsterile objects
Sterile objects become unsterile when below waist or out of vision
Prolonged exposure can lead to contamination
Fluids flow by gravity
Moisture increases conduction of microbes
Edges of sterile field (1 inch) are contaminated
Skin cannot be sterilized
Anything touched with your hands = contaminated
Use a scapel to cut skin
Nursing Diagnoses and Goals
Ex; Risk for contamination, risk for infection
Methods to Decrease Number of Microorganisms
Simple Cleaning (Clean Environment)
Physical Methods
Antiseptics
Disinfection
Sterilization
Antimicrobial agents- stop growth of infection
Simple Cleaning (Clean Environment)
Limit food at bedside, report any bugs that are on the unit
Physical Methods
Opening blinds/shades- UV light can kill some microorganisms
Antiseptics
Alcohol, chlorhexidine, showers
Disinfection
Sani-wipes (different color tops kill different microorganism)
Sterilization
More in the OR/surgical setting, destroys all of microorganisms
Ex; auto claving (under heat), boiling equipment, chemicals, radiation, ethylene gas
Antimicrobial agents
Stops growth of infection
Precautions
2 tiers
Tier 1: Standard Precaution
Tier 2: Transmission Based Precautions
Tier 1 (Standard Precaution)
Hand Hygiene: wash vs gel; nails
Washing is more effective than gel
No artificial nails! – they can chip and harbor bacteria under the polish
PPE (protective personal equipment) – gown, gloves, mask, etc.
Patient Care Materials – linens
Cleaning Equipment
Needle disposal (sharps container)
Patient placement
Isolate a patient if they have an infectious disease, cohort them if possible, etc.
Tier 2 (Transmission Based Precautions)
Airborne
Droplet- (respiratory infection)
Contact- (approach a patient)
Protective
Combination / Strict – (Droplet/Contact)
Decrease Host Susceptibility
Immunizations, nutrition, fluids, smoking cessation, control stress levels, chronic disease management, maintaining non-specific defenses
Immunizations
Increase immunity when you decrease your susceptibility (active immunity – artificial)
Nutrition
Increase protein (WBC production, tissue maintenance
Increase vitamin C
Zinc (boosts energy)
Fluids
Keeps skin moist (dry skin = possible breaks), thin secretions, flushes out microorganisms in the urinary tract
Smoking Cessations
Smoking destroys passageways
Control of Stress Level
Stress decrease immune system - inflammatory response
Maintaining Non-specific Defenses
Skin integrity: Breaks in skin = easy for microbes to enter
Hygiene (Personal Hygiene)
Science of health and its maintenance/preservation of health and cleanliness
Those who need help with hygiene
Blind
Morbidly obese
Those who have ROM issues
Stroke patients
Paralysis
Purposes of Hygiene
Interpersonal relationship with patient
Assess the patient’s skin, and whole body
Stimulates circulation (*** DO NOT massage calves – could dislodge thrombus)
Promotes health
Improves self-image
Promotes Cleanliness
Conditions skin
Clinical Manifestations indicating increased need (hygiene)
Smegma
Smegma
White cheesy like build up in the perineum
Patients & Hygiene
If they can assist during this time they can do so
Shower/bathing
Must have MD order
Eye Care
Cleanse with clean water
Clean with washcloth or cotton balls
Clean from inner canthus outward
Check for care of contact lenses, prosthetic eyes
Check for care of contact lenses , prosthetic eyes
Contacts should be taken out every so often
Prosthetics should be taken out daily and cleaned
Hair Care
Combing and brushing
Styling
Shampoo – may need a physician’s order depending on institution
Facial hair care
Combing and brushing
Should do this daily if possible
Redistributes the natural oils of the hair
Detangle
Facial Haircare
Shaving beards
Always used electric shaver!
Manual ones can cause cuts – pts on anticoagulants!
Nail Care
Epidermal appendages or extensions
No cutting but can file carefully
Soak fingers before cleaning under nails
Gently push cuticles back with a washcloth
Assess shape, angle, color of nail beds, texture, markings, and condition of surrounding tissue
Nails can be a big indicator of a patient’s nutritional status and habits (nail biting)
Oral Care
The mouth is very important to keep clean, many microbes can enter and proliferate here
Candidates for Oral Care
Everyone
Those with an NG tube
Altered mental status
Fever
Older adult (lack of saliva production)
Patients on O2 (can cause dry mouth)
Oral Care Equipment
Kidney basin, tooth brush, gloves, toothpaste, floss
Oral Care Methods
Place patient in lateral position if they have an altered level of consciousness
This position helps with excreting mucous (gravity)
NEVER put finger in patient’s mouth
They can bite you!
Maintaining Hygienic Environment
Bedmaking
Cleaning
Using Barriers
Bedmaking
Make sure sheets are taught (wrinkles can irritate the skin – skin breakdown!)
Unoccupied
Occupied
Cleaning
Use of disinfectant wipes
Disposal of possible contaminants
Do not save food! (food can spoil!)
Keep food fresh – keep refrigerated
Get rid of excess debris (tissues, garbage, etc.)
Principles of Bathing
Privacy, Involvement of patient, 3 steps to bathing, control of heat loss
Privacy in bathing
SUPER IMPORTANT! – always maintain the patient’s dignity. Pull the curtain and drape the patient’s area that isn’t being washed
Involvement of Patient
Always explain the procedure and what it entails (converse). Maintain autonomy- have them help as much as possible.
Components of Bathing
Washing, rinsing, drying
Control of Heat Loss
Prevent evaporation
Radiation
Conduction
Convection
Evaporation
Prevent (don’t leave skin wet- pat dry)
Radiation
Cover all parts not being used to maintain body temperature
Conduction
Heat transfers from warm objects to a cooler object. Use ideal water temperature (around 105)
Convection
Control air movement by closing doors, windows, etc.
Ex; Covering a patient w/ both blanket limits heat loss
Peri-care for the Male
Wash and dry the penis using firm strokes
Start at glans and work in circular motion away from the glans and along the shaft of the penis toward the body away from the urinary meatus
Wash and dry the scrotum
For the uncircumcised males, the foreskin or prepuce needs to be retracted to clean the glands and then replaced
Anus area last
Peri-care for the Female
Clean labia majora, then spread labia to wash and rinse between the folds of the labia majora and minora
Patient may find it embarrassing at first – but needs to be done properly
Work efficiently to expose patient as little of possible (No harsh chemicals, mostly for older adults)
Pat dry
Foley
Clean away from entry