Patho Micro Exam 2- Clostridium perfringens

Myonecrosis

gas gangrene

What are the symptoms of gas gangrene?

pain, edema, and cellulitis

Clostridial food poisoning is due to the action of what?

heat-labile enterotoxins

When should antibiotics be administered for clostridial SSTIs?

immediately

What is an indication someone has a clostridial SSTI?

gram-positive rods in tissue and an absence of leukocytes

Clostridium gram stain

gram positive

Clostridium relationship to oxygen

anaerobic

Are Clostridium part of our normal flora?

yes

Is Clostridium spore forming?

yes

Where is Clostridium perfringens found?

soil and flora of vagina and colon

Clostridium perfringens can cause what in wounds?

cellulitis

What is fasciitis characterized by in Clostridium perfringens infections?

pus in mucus plains, no muscle necrosis

What indicates that there is gas in the tissue?

crepitation

Why is there an absence of inflammatory cells in those with gas gangrene?

They are lysed by clostridal toxins

What are signs someone has gas gangrene?

hemolysis, jaundice, blood-tinged exudates

What is the mortality rate for gas gangrene?

high

Is Clostridial food poisoning an infection or an intoxication?

intoxication

Is Clostridial food poisoning severe or self-limiting?

Self-limiting

Is fever involved with Clostridial food poisoning?

no

Is nausea involved with Clostridial food poisoning?

no

Is vomiting involved with Clostridial food poisoning?

no

Is watery-diarrhea involved with Clostridial food poisoning?

yes

Is abdominal cramps involved with Clostridial food poisoning?

yes

Clostridial food poisoning is usually due to the ingestion of what?

meat products

For clostridial food poisoning, what temperature would be ideal for food to be stored at for spores to germinate to high numbers of bacteria?

Under 60C

If the SSTI is severe, how should it be treated?

high-dose penicilin therapy and surgical debridement

What is the treatment for clostridial food poisoning?

symptomatic