Unit 4: Cell Communication and The Cell Cycle

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What are the two main types of cell signaling based on distance?

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1

What are the two main types of cell signaling based on distance?

Local signaling (paracrine and synaptic) and long-distance signaling (endocrine).

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2

What are the three stages of cell signaling?

Reception, Transduction, and Response.

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3

What is a ligand?

A molecule that binds to a specific receptor on a target cell.

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4

What is the role of G protein-coupled receptors in cell signaling?

They activate G proteins that then bind to enzymes to trigger a response.

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5

Describe the function of ligand-gated ion channels.

They open or close in response to a ligand binding, allowing or blocking ion diffusion.

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6

What is phosphorylation, and why is it important in cell signaling?

Phosphorylation is the addition of a phosphate group to a protein, which can activate it and propagate a signal.

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7

What are second messengers? Give an example.

Small molecules that spread the signal within the cell; an example is cyclic AMP (cAMP).

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8

What is negative feedback?

A mechanism that reduces or stops a response to return to a stable state, like insulin lowering blood glucose.

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9

What is positive feedback?

A mechanism that reinforces a response, increasing it, like oxytocin in childbirth.

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10

What is the function of endocrine glands?

They release hormones into the bloodstream to regulate various body functions.

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11

Distinguish between peptide and steroid hormones.

Peptide hormones are water-soluble and bind to cell membrane receptors, while steroid hormones are lipid-soluble and pass into cells to bind to internal receptors.

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12

Give an example of a hormone cascade.

Thyroid hormone release controlled by the pituitary gland.

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13

How does an action potential propagate along a neuron?

It travels from dendrite → cell body → axon, jumping at nodes of Ranvier (saltatory conduction).

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14

What happens at a synapse?

Neurotransmitters are released and bind to receptors on the next neuron, triggering a response.

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15

What are the three lines of defense in the immune system?

1. Barrier defenses, 2. Non-specific (innate) immunity, 3. Specific (adaptive) immunity.

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16

What are B cells and T cells, and how do they function in immunity?

B cells produce antibodies in humoral immunity, while T cells destroy infected cells in cell-mediated immunity.

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17

What is the cell cycle?

The life cycle of a cell from its formation to division into two daughter cells.

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18

Why is the cell cycle important?

It enables growth, repair, and the production of identical cells.

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19

What are the phases of interphase?

G1 phase (growth), S phase (DNA replication), and G2 phase (preparation for mitosis).

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20

List the stages of mitosis.

Prophase, Prometaphase, Metaphase, Anaphase, Telophase.

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21

What happens during metaphase in mitosis?

Chromosomes align at the metaphase plate.

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22

What is cytokinesis?

The division of the cytoplasm, completing cell division.

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23

How is cytokinesis different in plant and animal cells?

In animal cells, it occurs through cleavage, and in plant cells, through the formation of a cell plate.

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