Cardiorespiratory Physiotherapy

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231 Terms

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6 core cardiorespiratory problems

  1. Respiratory failure (Type 1 and 2)

  2. Sputum retention

  3. Loss of volume

  4. Increased work of breathing

  5. Pain

  6. Reduced exercise tolerance

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What are the 5 Carinal Signs of Respiratory Disease?

  1. Dyspnea

  2. Cough

  3. Sputum

  4. Wheeze

  5. Chest Pain

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Cardinal Sign - Dyspnea

+ and the 4 classes

  • increase work of breathing/shortness of breath

  • can be related to: Orthopnea (lying down), Paroxysmal nocturnal dyspnoea (SOH when asleep)

  • Important to gain info on: Duration, severity, pattern and associated factors

  • Classified into 4 classes

    • Class 1: no physical activity limitation

    • Class 2: slight physical activity limitation

    • Class 3: marked physical activity limitation

    • Class 4: unable to perform physical activity

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Cardinal Sign - Cough

  • Protective reflex

  • Caused by: inflammation, irritation, habit, excess secretions

  • Check: frequency (day/night), effectiveness (weak/strong/pain), Quality (wet/dry/raspy)

  • Complications: fractured ribs, hernias, incontinence, embarrassing

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Cardinal Sign - Sputum

  • excess tracheobronchial secretions, combination of saliva and mucus result of infection/disease

  • cleared by huffing/coughing, improving gas exchange & expiratory flow

  • may contain: mucus, cellular debris, microorganisms, blood (hemoptysis), foreign particles

  • Checklist: quantity (small/5c coin/cup), quality (consistency/colour/odour)

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The ABCDE Approach

Airway- Blocked? Upper airway collapse? Aspiration? Tracheostomy? Ventilated? Do they require O2?

Breathing - Work of breathing? Pattern? Distress? Auscultation? Fatigue/weakness? Accessory muscle use?

Circulation - Colouring? Temp? BP/HR? Blood results? Stability for intervention? Oedema?

Disability - Previous medical history? Limiting factors? Impact on my ability to treat? surgery? Pain?

Environment/Exposure - Wounds/scars? Temperature? Palpation? Medication? Antibiotics/steroids?

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Observations of the Head and Neck

  • Facial expression

  • Colour/pallor

  • Use of accessory muscles

  • Sculpturing: how much of the muscles can you see

  • pursed lip breathing

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How to Auscultate?

knowt flashcard image
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Breath sounds - Wheeze

  • vibration of the walls of a narrowed airway

  • pitch determined by diameter and elasticity of the airway

  • expiratory wheeze - bronchospasm

  • inspiration wheeze - airway obstructions, oedema, mucous

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Breath sounds - Crackles

  • discontinuous, short, explosive sounds

  • fine or course sounds

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What colours do Air, Fat, Soft tissues and Bone correlate to in an X-ray?

Air = Black

Fat = Dark grey

Soft tissue = grey

Bone = white

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X-ray Exposure

  • Should be able to see T4 (not T5) vertebrae on PA

  • Over-exposed = appears black

  • Under-exposed = appears falsely white

<ul><li><p>Should be <strong>able to see T4 (not T5)</strong> <strong>vertebrae</strong> on PA</p></li><li><p>Over-exposed = appears black</p></li><li><p>Under-exposed = appears falsely white</p></li></ul><p></p>
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X-ray Reading - Logical Progression - ABCDEFGHIM

Airways - Trachea should be central but deviates slightly to right

Bones - compare bone density

Cardiac silhouette - check heart is normal shape

Diaphragm - right is higher than left, should be smooth

Edges - should be well defined acute angles

Fields - should be equal, compare size

Gas - abdominal gas bubbles

Hilum - left higher than right, compare shape and density

Instrumentation - ETT, tracheostomy tube, catheter, nasogastric tubes, pacemaker

Mediastinum - border should be fuzzy and trachea visible

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Pathology - Consolidation

  • Air filled paces replaced with fluid, blood or sputum

  • E.g. Pneumonia

<ul><li><p><strong>Air filled paces replaced with fluid, blood or sputum</strong></p></li><li><p>E.g. Pneumonia</p></li></ul><p></p>
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Pathology - Collapse

  • Elevation of hemidiaphragm

  • decrease in rib spacing

  • displacement of mediastinum, hilum, fissure - volume loss

<ul><li><p><strong>Elevation of hemidiaphragm</strong></p></li><li><p>decrease in rib spacing</p></li><li><p>displacement of mediastinum, hilum, fissure - <strong>volume loss</strong></p></li></ul><p></p>
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Pathology - Pleural Effusion

  • Accumulation of fluid in pleural cavity

  • collects in costophrenic angles

  • Meniscus sign”

  • lateral lying x-ray

<ul><li><p><strong>Accumulation of fluid in pleural cavity</strong></p></li><li><p>collects in costophrenic angles</p></li><li><p>“<strong>Meniscus</strong> sign”</p></li><li><p>lateral lying x-ray</p></li></ul><p></p>
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Pathology - Pneumothorax

  • lack of lung marking

  • deep sulcus sign

  • sharply outlined diaphragm

<ul><li><p>lack of lung marking</p></li><li><p><strong>deep sulcus sign</strong></p></li><li><p>sharply outlined diaphragm</p></li></ul><p></p>
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Pathology - Tension Pneumothorax

  • ipsilateral diaphragm depressed and flattened

  • mediastinum and heart pushed to other side

<ul><li><p>ipsilateral diaphragm depressed and flattened </p></li><li><p>mediastinum and heart pushed to other side</p></li></ul><p></p>
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Pathology - Haemothorax

  • blood in lungs

  • air-fluid level

  • no meniscus sign → flax line

<ul><li><p>blood in lungs </p></li><li><p>air-fluid level </p></li><li><p>no meniscus sign → flax line</p></li></ul><p></p>
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Pathology - Subcutaneous Emphysema

  • dark streaks in soft tissues

  • Air appears black (radiolucent) on X-ray

  • streaky, bubbly, or reticular (net-like) black areas in the soft tissue

<ul><li><p>dark streaks in soft tissues </p></li><li><p>Air appears black (radiolucent) on X-ray</p></li><li><p>streaky, bubbly, or reticular (net-like) black areas in the soft tissue</p></li></ul><p></p>
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Pathology - Bronchiectasis

  • Dilatation caused by congenital deficiency and weakening of the muscular and elastic layers in the bronchial walls

  • ring shadows

  • increased bronchiole diameter

<ul><li><p><span>Dilatation caused by congenital deficiency and weakening of the muscular and elastic layers in the bronchial walls</span></p></li><li><p><span>ring shadows</span></p></li><li><p><span>increased bronchiole diameter</span></p></li></ul><p></p>
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Pathology - Cystic Fibrosis

  • may show hyperinflation

  • dilated bronchi

  • over time, inflammation can cause scarring, leading to a mosaic pattern

<ul><li><p>may show <strong>hyperinflation</strong></p></li><li><p><strong>dilated bronchi</strong></p></li><li><p>over time, inflammation can cause <strong>scarring</strong>, leading to a <u>mosaic pattern</u></p></li></ul><p></p>
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Pathology - Pulmonary Oedema

  • batwing” pattern

  • increased cardiac silhouette sign

  • pleural effusions present

<ul><li><p>“<strong>batwing</strong>” pattern</p></li><li><p>increased cardiac silhouette sign</p></li><li><p>pleural effusions present</p></li></ul><p></p>
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What is Perfusion?

Total volume of blood reaching the pulmonary capillaries

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What is the ventilation-perfusion ratio when standing?

  • 3.3 in the apex of the lung and 0.63 in the base

  • Ventilation exceeds perfusion in apex, and perfusion exceeds ventilation in base

  • The overall value in the average human lung is 0.8 V/Q

<ul><li><p><strong>3.3 in the apex</strong> of the lung and <strong>0.63 in the base</strong></p></li><li><p>Ventilation exceeds perfusion in apex, and perfusion exceeds ventilation in base</p></li><li><p>The overall value in the average human lung is <strong><u>0.8 V/Q</u></strong></p></li></ul><p></p>
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In regular upright ventilation, where does more ventilation go? And why?

into the lung base rather than the lung apex

  • more alveoli at the larger lung bases

  • basal alveoli are less stretched than the apical alveoli

<p>into the lung base rather than the lung apex</p><ul><li><p>more alveoli at the larger lung bases</p></li><li><p>basal alveoli are less stretched than the apical alveoli</p></li></ul><p></p>
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What is the “dependent region” in relation to distensibility?

dependent region: basal region of the lung in relation to gravity

  • basal alveoli are more compliant (distensibility), therefore is more ventilated at the basal alveoli

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In regular upright ventilation, where does more perfusion go? And why?

into the lung base rather than the lung apex

  • more alveoli and pulmonary blood vessels at base

  • gravitational effects on pulmonary blood

Both ventilation and perfusion are greater at the lung bases in upright posture, but perfusion increases more steeply than ventilation

<p>into the lung base rather than the lung apex</p><ul><li><p>more alveoli and pulmonary blood vessels at base</p></li><li><p>gravitational effects on pulmonary blood</p></li></ul><p></p><p>Both <strong>ventilation and perfusion are greater at the lung bases</strong> in upright posture, but <strong>perfusion increases more steeply than ventilation</strong></p><p></p>
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what happens if there is a mismatch between alveolar ventilation and blood flow?

  • it will be seen in the V/Q ratio

  • if the V/Q ratio reduces due to inadequate ventilation, gas exchange within the affected alveoli will be impaired.

  • ^ capillary partial pressure (PO2) falls and PCO2 rises

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What are some reduced ventilation problems?

  • affects oxygen levels as carbon dioxide is more soluble and continues to diffuse despite impairment

  • Type 1 Respiratory Impairment

    (PaO2 less than 80mmHg) → Type 1 Respiratory Impairment

    (PaO2 less than 60mmHg) → Type 2 Respiratory Failure

  • Pneumonia, Asthma, COPD, Hypoxia

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What are some reduced perfusion problems?

  • pulmonary embolism → circulation is obstructed

  • other areas will receive increased blood supply

  • hypoxemia to the lung

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What are some contraindications to a head down tilt position?

  • cardiac failure

  • Unstable HR

  • Hypertension

  • cerebral oedema (swelling of brain)

  • hemoptysis (coughing up blood)

  • obesity

  • pregnancy

  • surgery/head or neck trauma

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What is SpO2?

peripheral oxygen saturations measured by pulse oximetry (finger/earlobe/forehead)

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What is SaO2?

arterial oxygen saturations measured by ABG

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How to document Oxygen Use? “7 steps”

  • Document starting device/flow;

  • Start O2 and ensure target is achieved quickly;

  • Titrate O2 to keep in SpO2 range

  • Monitor O2 minimum 4 hourly

  • Record SpO2 & delivery device

    • Wean off O2 if clinically stable

  • Codes to be written on obs. chart and initialled.

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When are ABGs required with Oxygen therapy?

  • Critically ill patients with cardiorespiratory or metabolic dysfunction

  • In patients with a SpO2<92%

  • Deteriorating oxygen saturation requiring increased FiO2

  • Patients at risk of hypercapnia

  • Breathless patients in whom a reliable oximetry signal cannot be obtained

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What is the normal peak inspiratory flow rate (PIFR)

ranges between 20-30 L.min-1

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What is FiO2?

Minimum flow rate required to ensure a patient receives an exact concentration of oxygen

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What are some Low Flow Oxygen Devices

  • Nasal cannula (long-term O2 therapy, hypoxic patients)

  • Hudson face mask (short-term use, following surgery)

  • Reservoir mark (emergencies, severe hypoxaemia)

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What are some examples of High Flow Oxygen Devices?

  • High-flow nasal cannula therapy (HFNC) (100% O2 delivery, increased tidal volume, minimal air room entrainment)

  • Venturi Mask (increase flow of gas without increasing amount of O2)

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Physiotherapy role in Oxygen delivery

  • Ensure correct mode of delivery

  • Assess the need for oxygen with exercise

  • Advise whether oxygen is sufficient

  • Can alter prescription in certain situations

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Benefits of Humidification

  • Improves mucociliary function

  • Facilitates secretion removal

  • Reduce work of breathing

  • Improved patient comfort and compliance

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Methods of Humidification

  • Systemic Hydration (drinking/IV water)

  • Bubble through (cold water)

  • Heated water bath (humidifier)

  • Pass over humidification

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What is the ventilation-perfusion ratio?

ratio of alveolar ventilation (V̇A) to pulmonary blood flow (e.g. V/Q)

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In the ventilation-perfusion relationship, where in the lung is there more perfusion and ventilation?

  • more perfusion at bases

  • more ventilation at the apical regions

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Nasal cannula: What is the recommended dosage for oxygen?

No more than 4 L.min-1 O2

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Hudson face mask: What is the recommended dosage for oxygen?

Minimum of 5 L.min-1 O2

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Reservoir Mark: What is the recommended dosage for oxygen?

Minimum 12 L.min-1 O2

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What are the 5 physiological mechanisms responsible for the efficacy of high-flow nasal cannula?

  1. Increases function residual capacity (FRC)

  2. Washout of waste gases including carbon dioxide (CO2)

  3. Decreased respiratory rate

  4. Provides Positive end-expiratory pressure (PEEP) ~2-4cmH2O

  5. Increased tidal volume (VT)

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Administration range for SpO2 in a patient with an acute condition:

Administration range for SpO2 in a patient with COPD:

acute condition: less than 92% and titrated to 92-96%

patient with COPD: less than 88% and titrated to 88-92%

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What is a PF Ratio? (PaO₂ /FiO₂)

A measure of how well oxygen is being transferred from the lungs into the blood (assess severity of hypoxemia)

Determined by dividing Blood/Oxygen = (hopefully more than 400)

Normal: >400

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What is a “A-A” gradient? + normal range

The difference in partial pressure of oxygen between arterial blood and alveolar gas

Normal: 5-10mmHg

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Requirement for normal airway clearance - Mucociliary escalator

  • Whipping action of the cilium within the sol layer of the mucus produces a wave motion

  • Stroking action speed = 2cm per min

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Requirement for normal airway clearance - effective cough and phases

  • A voluntary cough is generally characterised by an inspiration of approximately 80-90% total lung capacity

  • The contraction of abdominal muscles and expiratory muscles generates a sudden increase in intrathoracic pressure, before the glottis is rapidly opened, and a blast of turbulent air is expelled

  • 3 phases → inspiration, compression, expulsion

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Peak Cough Flow in Adults

Normal: 720 L.min-1

Minimum required for effective airway clearance: >160 L.min-1

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Factors decreasing mucociliary clearance

  • medications

  • mucosa drying

  • High FiO2

  • Endotracheal tube

  • Pollutants

  • Decreased lung volumes

  • Dehydration

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Reasons for an Ineffective Cough?

  • Decreased lung volume

  • pain, restriction, weakness

^ Solution: use breath-stacking to increase lung volume

  • Decreased expiratory force

  • poor elastic recoil, can’t close glottis

^ Solution: assist expiratory phase

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7 Examples of Physiotherapy techniques to improve Airway Clearance Therapy (ACT)?

  • Gravity-assisted positioning (GAP)

  • Airway clearance devices

  • Manual techniques (chest wall vibrations, percussion)

  • Drainage

  • Nebulized inhalation therapy

  • Exercise

  • Assist cough

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Indications and Considerations for Airway Clearance Therapy (ACT)

Indications

  • Diseases (COPD, CF etc), post-operation, collapsible airways, productive asthma

Considerations

  • consent, infection control, patient comfort

If a patient has bronchoconstriction (wheeze), consider Salbutamol or nebulized mucolytic

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OSCE: Active Cycle of Breathing Technique (ACBT)

Components (varies with each patient)

  • Breathing Control (gentle breathing, lower chest) ~2mins

  • Thoracic expansion exercise (deep breathing, hands on ribs, with or without hold) (x3)

  • Forced expiratory technique HUFF (x2) (squeeze not wheeze, “Fogging up a mirror”)

What for?

  • secretion clearance, improving ventilation, no equipment required, moist environments (shower)

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What is an Equal Pressure Point mechanism?

  • describes how, during forced expiration, the point where ‘airway pressure = pleural pressure’ determines where the airway is prone to collapse, limiting expiratory flow.

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Ideal positioning for Airway Clearance Therapy (ACT)

  • Sitting position with arms supported that promotes an increase in FRC

  • (Sitting supported)

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OSCE: Positive Expiratory Pressure Devices - PEP mask

  • prevents small airway collapse

  • The patient performs controlled expiration against the resistance, to maintain respiratory pressures between 10-20cmH20

  • Consider size and patients expiratory flow

  • 10-12 cycles of 8-10 exhalations= until secretions are cleared

<ul><li><p><strong>prevents small airway collapse</strong></p></li><li><p>The patient performs controlled expiration <strong>against the resistance</strong>, to maintain respiratory pressures between <strong>10-20cmH20</strong></p></li><li><p>Consider size and patients expiratory flow</p></li></ul><ul><li><p>10-12 cycles of 8-10 exhalations= until secretions are cleared</p></li></ul><p></p>
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OSCE: 3 Types of Oscillating Devices with PEP

  1. Acapella

    • creates oscillation effect on airways with PEP

  2. Flutter

    • creates oscillation effect on airways, with a steel ball interrupting the flow of air

    • Position dependent

  3. Aerobika

    • dial up resistance, independent of gravity

All treatments consist of 10-12 cycle of 10-12 exhalations

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3 Stages of Autogenic Drainage

Stage 1: low volume breaths to mobilize secretions

Stage 2: medium (tidal) beaths to collect mucus

Stage 3: Large volume breaths to enable expectoration

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OSCE: Manual Technique - Chest wall Vibrations (CWV)

  • increases peak expiratory flow

  • helps to shift secretions from lung peripheries

  • never perform on a breathless patient

  • creates airway oscillation

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Manual Technique - Exercise

  • performed before ACTs to loosen secretions

  • increased BMI and posture, well-being, cardiovascular fitness etc

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What is Atelectasis?

  • The collapse of a part/all of an alveolus, leading to reduced gas exchange and respiratory problems (Loss of volume).

  • Usually from surgery, smoking, obesity, age, impaired cognition etc

Type: Obstructive (bronchial obstruction)

Type: Non-Obstructive (surgery, wound etc)

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6 Signs and Symptoms of a Post-Op chest Infection

  • SpO2 less than 90% on 2 consecutive days

  • Chest x-ray findings

  • Temp over 38deg 1-day post-op

  • Productive Sputum

  • Abnormal lung auscultation

  • Raised white cell count

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4 Clinical Signs of Atelectasis?

  • Reduced PaO2

  • Reduced lung compliance

  • Reduced FRC

  • Non-productive cough

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What is Collateral Ventilation?

Thoracic expansion exercises

  • Increase collateral ventilation

  • Increase lung volume

  • Mobilise secretions as air can get behind the sputum.

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Importance of Mobilization

  • uptake of O2

  • reduction in FiO2

  • increase in cardiac output and oxygen extraction in tissues

  • exercise increases SV and HR therefore increases CO

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What is Alveolar Interdependence?

When an alveolus begins to collapse, the surrounding alveoli pull open the collapsing one (using expanding forces and neighboring tension)

  • protective mechanism against atelectasis

  • Expanding forces exerted between adjacent alveoli & higher lung volume > expanding forces

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OSCE: Positive Expiratory Pressure - Pari PEP

  • splinting open airways prone to dynamic compression during forced expiration

  • Can be used in conjunction with a Nebulizer

  • not position dependent

  • Maintain 10-20cmH2O

  • Backwards pressure to hold airways open

<ul><li><p><strong>splinting open airways</strong> prone to dynamic compression during forced expiration</p></li><li><p>Can be used in <strong>conjunction with a Nebulizer</strong></p></li><li><p><strong>not position dependen</strong>t </p></li><li><p>Maintain <strong>10-20cmH2O</strong></p></li><li><p><strong>Backwards pressure to hold airways open</strong></p></li></ul><p></p>
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OSCE: Nebulized Inhaled Therapy

  • Inhalation of saline solution through Pari PEP to increase water to lungs to thin out sputum for it to be coughed up easier

  • Breathe in and out normally

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OSCE: Incentive Spirometry

  • provide visual feedback via a ball/chip rising to the preset marker via inspiration

  • track lung volumes

<ul><li><p>provide <strong>visual feedback</strong> via a <strong>ball/chip rising</strong> to the preset marker via <em>inspiration</em></p></li><li><p>track lung volumes</p></li></ul><p></p>
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Movement of the Ribs

Ribs 1-6: _______

Ribs 7-10: _______
Ribs 10-12: ________

Ribs 1-6: “Pump handle” - up and down movement

Ribs 7-10: “Bucket handle” - contraction of diaphragm
Ribs 10-12: “Caliper motion” - outwards and backwards swing

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What are the 3 Basic elements of the Respiratory Control System? (C.E.S.)

  1. Central Controller (brainstem)

  2. Effectors (causes of ventilation)

  3. Sensors (chemoreceptors to adjust output (Co2, H+ and O2)

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What is the Normal PaCO2, and some problems that can arise?

Normal PaCO2 = 35-45mmHg

  • Type 2 Respiratory Failure (PaCO2 more than 50mmHg (hypoxemia) & PaO2 less than 60mmHg (hypercapnia))

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What is Ventilation? + normal ranges

The movement of air between the environment and the lungs via inhalation and exhalation

  • Normal at rest: 5-8L/min

  • Light exercise: 12L/min

  • Moderate exercise: 40-60L/min

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What is Work of Breathing (WOB)?

The amount of work that the respiratory muscles have to exert during a single respiratory cycle

  • Airflow resistance

  • Increased elastic load

  • Loss of elastic recoil

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4 Causes of Respiratory muscle dysfunction?

  1. Change is length-tension relationships (hyperinflation)

  2. Myopathy (steroid-induced)

  3. Neuromuscular disease

  4. Connective tissue disorders

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What is Dynamic Hyperinflation?

air gets trapped in the lungs during rapid or obstructed breathing, causing lung volumes to gradually increase above their normal resting level.

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Objective Findings for Dyspnea (B.R.A.A.C)

  • Abnormal breathing pattern

  • Increased RR

  • Apical breathing (upper chest)

  • Accessory muscl use

  • Weak cough

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How to assess Work of Breathing? (R.F.P.R)

  • Patient rates their symptoms

  • Impact on functional abilities

  • Clarify pattern of breathlessness

  • Look for reversible causes

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H.I.F.L.O.W. Humidification Benefits

H - Heated & humidified

I - Inspiratory demands

F - Functional residual capacity

L- Lighter = more tolerable

O - Oxygen dilution

W - Washout of dead space (CO2 removal)

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6 Physiologic mechanisms for efficacy of High Flow Nasal Cannula

  1. Increases FRC

  2. Physiological dead space washout of waste gases

  3. Decreased respiratory rate

  4. Provides positive end-expiratory pressure (PEEP)

  5. Increased tidal volume

  6. Increased lung recruitment

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4 Outcome measures for Dyspnea

M

V

B

15

  1. Medical Research Council Dyspnea Scale (MRC Scale)

  2. Visual Analogue Scale (VAS)

  3. Modified 0-10 Borg Breathlessness scale

  4. 15-count breathlessness score

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5 Rights of Clinical Reasoning

  1. Right Cue

  2. Right Patient

  3. Right Time

  4. Right Action

  5. Right Reason

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pH level less than 7.35 / PaCO2 more than 50mmHg / HCO3 22-26 (normal) is what _________?

Uncompensated Respiratory Acidosis

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pH level less than 7.35 / PaCO2 more than 50mmHg / HCO3 more than 26 is what _________?

Partially Compensated Respiratory Acidosis

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pH level between 7.35-7.45 (normal) / PaCO2 more than 50mmHg / HCO3 more than 26 is what _________?

Compensated Respiratory Acidosis

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pH level more than 7.45 / PaCO2 between 35-45mmHg (normal) / HCO3 more than 26 is what _________

Uncompensated Respiratory Alkalosis

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pH level more than 7.45 / PaCO2 more than 50mmHg / HCO3 more than 26 is what _________

Partially Compensated Respiratory Alkalosis

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pH level between 7.35-7.45 (normal) / PaCO2 less than 35mmHg / HCO3 less than 22 is what _________

Compensated Metabolic Alkalosis

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OSCE: Positions of Comfort & Ease

  1. High side lying

  2. Supported side lying (optimal treatment position)

  3. Unsupported 45-60deg

  4. Supported in 45-60deg

  5. Upright sitting supported

  1. Slumped over railing, chair or table

  • Increase the curvature of diaphragmatic fibres (effectively contract)

  • Provide support for the arms/shoulder optimising accessory muscle function

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OSCE: Breathlessness Techniques

Pacing

  • Breathing may be timed with stepping during walking or stair climbing

  • co-ordinate breathing control with activity.

Pursed lip breathing

  • Exhaling against pursed lips helps to splint open the airways and improve oxygenation…but it increases the work of expiration.

Blow as you go

  • breathe out on effort

Fan therapy

  • stimulates the trigeminal nerve reducing perception of breathlessness

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Bronchiectasis

What is it: irreversible dilatation and destruction of the bronchial walls, leading to impaired clearance of mucus, recurrent infections, and airway inflammation.

Caused by: post-infection, immunodeficiency, tumors, enlarged lymph nodes

Clinical Features: Productive cough, foul sputum, hemoptysis, dyspnea

Management: ACT, antibiotics, bronchodilators, surgery, vaccines

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Cystic Fibrosis

What is it: genetic, autosomal recessive disorder caused by mutations in the CFTR gene (Cystic Fibrosis Transmembrane Conductance Regulator).

Clinical Features: chronic cough, wheeze, finger clubbing, diabetes, malabsorption, steatorrhea (fat in feces)

Management: ACT, antibiotics, lung transplant, diet changes, CFTR modulators

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Pneumonia

What is it: acute infection of the lung alveoli, interstitium, and distal airways, causing inflammation and consolidation

Caused by: CAP (community-acquired), HAP (hospital-acquired), immunocompromised

Clinical Features: fever, chills, cough, dyspnea, tachycardia, confusion, consolidation, bronchial breath sounds/crackles

Management: oxygen, IV fluids, antibiotics, steroids