Chapter 23 Microbial Diseases of the Cardiovascular system

The body has host defenses. What are the physical defenses

1. skin

2. mucous membranes

3. fever

what are the body’s chemical defenses

• immunological proteins

• Immune system

what are the bodys biological host defenses

cells of the immune system

pathogens usually gain access to the body via ___________

parenteral route

• invasive medical procedures, cuts, bites, abrasions

___________: persistence of pathogens in the BLOOD

septicemia

SIRS stands for…

systemic inflammatory response syndrome

what is being describes…

• threatening condition where the body's response to an infection damages its own tissues and organs

septic shock

what is pureperal sepsis

childbirth/childbed fever

Transmitted to mother during childbirth by attending physicians and midwives

what is being described.

childbirth/childbed fever

Transmitted to mother during childbirth by attending physicians and midwives

puerperal sepsis

Puerperal sepsis is caused by strepto______

streptococcus pyogenes

what is endocarditis

inflammation of the endocardium

what is the treatment for endocarditis

antibiotic therapy to specific pathogen

what is rheumatic fever

inflammation of the heart valves

which disease has a nodule by the elbow

rhuematic fever

describe the process of the anthrax infection

acquired via inhalation, ingestion, or parenteral infection with spores

what is being described:

• non motile, spore forming gram positive aerobe

anthrax

which form of anthrax is this

• rarest form of infection

• bloody diarrhea

• abdominal pain

• lesions throughout gastrointestinal tract

gastrointestinal anthrax

which form of anthrax infection is being described:

• 90% of cases

• formation of eschar at infection site

• lethargy and moderate fever

cutaneos anthrax

which form of anthrax infection is being described:

• almost 100% fatal

• early symptoms include low grade fever and cough

pulmonary anthrax

treatment of anthrax consists of

doxycycline and ciprofloxacin

_________ is the loss of blood supply to tissue

ischemia

_______ is the death of tissue

necrosis

________: is the death of soft tissue

gangrene

describe the transmission of the plague (black death)

bite of infected rat flea; contaminated bodily fluids

There are three variants of the plague:

• bacteria enters lymph from bite of flea

• inflammation and necrosis

• appearance of bubos

• high fever, shaking, chills, fatigue, headache

bubonic plague

There are three variants of the black death:

• necrosis, pupura and subcutaneus hemmorrage,

• septic shock

systemic (black death)

There are three variants of the plague:

• most deadly form

• necortic lesions

• hemmorrhage in lungs

pneumonic

bubonic plague is :

• bubo formation in axillary

systemic plague is:

development of purpura and nectoric tissue resulting from DIC, followed by septic shock

Pneumonic plague is:

impaired respiration from the formation of necrotic nodules and pulmonary hemmorhage

what is the reservoir for lyme disease

DEER

what is the vector for lyme disease

ticks

describe stage one of lyme disease

flu like symptoms, bulls eye rash

stage 2 of lyme disease

bells palsy meningitis, encephalitis. severe headache, amnesia, paralysis, extreme pain in large joints

stage 3 of lymes

numbness, fatigue, short-term memory loss

what stage is this:

numbness, fatigue, short-term memory loss

3

what stage is this:

• meningitis, encephalitis, severe headache, amnesia, paralysis

stage 2

what stage is this:

Bulls eye rash, flue like symptoms

stage 1

what is the pathogen that causes septic shock

grem negative enterococci, group be streptococci

what is the portal of entry for septic shock

skin

what is the reservoir for septic shock

human body

what is the MOD for septic shock

injection;catheterization

what are symptoms for septic shock

fever, chills, increased heart rate, lymphangitis

what is the pathogen and portal of entry for puerperal sepsis

streptococcus pyogenes, vagina

what is the resevior and MOD for puerperal sepsis

human nasopharynx, nonsocomial

what is the pathogen and portal of entry for rheumatic fever

group a beta hemolytic streptococci

probbaly an autoimmune streptoccci infections

symptoms of rheumatic fever

arthritis, fever;damage to heart valves

treatment for rheumatic fever

none!!!!!!

what is the pathogen and portal of entry for anthrax

bacillus anthracis

mouth;skin;respiratory tract

what is the resevior and MOD for anthrax

soil; large grazing mammals

direct contact;ingestion; inhalation

what are the symptoms for anthrax

papule bloody diarrhea, septic shock

treatment for anthrax

ciprofloxacin;doxycycline

what is the pathogen and portal of entry for gangreen

clostridium perfringenes

skin

what is the reservoir and MOD for gangreen

soil

puncture wound

symptoms fro gangreen

tissue necrosis

SURGICAL REMOVAL IS THE TREATMENT

what is the pathogen and portal of entry for PLAGUE

yersnia pestis

skin;respiratory tract

what is the resevior and MOD for plague

rodents

fleas; inhalation

symptoms and treatment for PLAGUE

enlarged lymoh notes; septic shock

streptoimycin and tetracycline

what is the pathogen and portal of entry for lymes disease

borrelia burgdoferi

skin

what is the reservoir and MOD for lymes disease

field mice;deer

Ixoden ticks

symptoms and treatment for lymes

bulls eye rash…

antibiotics

______ are viruses traveling in the blood or lymph to cause systemic infection

viramia

what viral infection is being described:

fever, severe sore throat, cervical lymphadenopathy, exhaustion, possible spleen enlargement

infectious mononucleosis

this viral disease affects the liver but usually spread via contact with bodily fluids such as blood

hepatitis

this fungal disease: presence of indwelling catheters, fevers and chills, sepsis, death

candida auris

what protozoan disease is being described

• repeating cycles of fever, chills, and sweating accomponied by headahce, delirium, nausea…

malaria

prevention of malaria includes…

bed netting and vector control

treatment of malaria involves…

quinine and chloroquinine