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Bioavailability
Fraction of active form of drug that reaches plasma.
Intravenous (IV)
Administration method that has 100% bioavailability because the drug is delivered directly into the bloodstream.
Oral drugs
Bioavailability is usually less than 100% due to incomplete absorption and first-pass metabolism in the liver.
First-pass metabolism
The process where the drug is partially broken down before reaching systemic circulation.
Dosage determination
A drug with low oral bioavailability may need a higher dose or different route.
Ac
Abbreviation for 'Before meals'.
Po
Abbreviation for 'By mouth'.
Cap
Abbreviation for 'Capsule'.
G
Abbreviation for 'Gram'.
Gtt
Abbreviation for 'Drop'.
H
Abbreviation for 'Hour'.
Hs
Abbreviation for 'Bedtime'.
IM
Abbreviation for 'Intramuscular'.
IV
Abbreviation for 'Intravenous'.
Mg
Abbreviation for 'Milligram'.
SC, SQ
Abbreviation for 'Subcutaneous'.
Pc
Abbreviation for 'After meals'.
Prn
Abbreviation for 'As needed'.
Q
Abbreviation for 'Every'.
QAM, OM
Abbreviation for 'Every morning'.
QHS
Abbreviation for 'Every night at bedtime'.
QID
Abbreviation for 'Four times a day'.
Stat
Abbreviation for 'At once'.
Sup, sup
Abbreviation for 'Suppository'.
OD
Abbreviation for 'Right eye'.
Susp
Abbreviation for 'Suspension'.
OS, OL
Abbreviation for 'Left eye'.
Tab
Abbreviation for 'Tablet'.
OTC
Abbreviation for 'Over-the-counter'.
Tid
Abbreviation for 'Three times a day'.
OU
Abbreviation for 'Both eyes'.