Iceberg demonstrates the relationship between direct and indirect costs of accidents, showing that on average, indirect costs exceed direct costs. Examples of indirect costs include: - a) Overhead costs - b) Schedule delays - c) **Medical costs** (DIRECT COST) - d) Cleanup time ## 7. Geometric Sequences - **Sequence Identification:** The proper arrangement of the following shapes by their complexity is: I. Quadrilateral II. Parallelogram III. Rectangle IV. Square. - a) II, IV, III, I - b) I, II, III, IV - c) IV, III, II, I - d) I, III, II, IV ## 8. Building Use Classification - The term **Occupancy** refers to a type of use of a building for interior space such as an office, restaurant, private residence, or school, grouped based on similar life-safety characteristics, fire hazards, and combustible contents. - a) Building elements - b) **Occupancy** - c) Building Code - d) Accommodation ## 9. Construction Pit Transport Fees - The maximum distance, as specified in the construction contract, which the contractor is expected to transport soil material without receiving additional payment, is known as **Freehaul distance**. - a) **Freehaul distance** - b) Overhaul distance - c) Haul distance - d) Baseline distance ## 10. Retarder Application Principles - **Fundamental Principles for Upper Retarders:** The retarder should be as near as possible to the warm side of the insulation or the warm face of the assembly. Moreover, it should be installed using a method appropriate for the specific condensation hazard. ## 11. Material Characteristics - **Hardness**: A measure of a material's ability to resist indentation or penetration. - a) **Hardness** - b) Ductility - c) Toughness - d) Resilience ## 12. Soil Density Changes - **Consolidation**: An increase in the soil density of cohesive soil resulting from the expulsion of water from the soil's void spaces. - a) Segregation - b) **Consolidation** - c) Compaction - d) Soil Stabilization ## 13. Concrete Finishing Process - The correct step-by-step process of finishing standard weight concrete slabs is as follows: 1. Bleeding 2. Screeding 3. Leveling 4. Edging 5. Jointing 6. Floating 7. Troweling 8. Broom finishing ## 14. Safety Oversight Authority - The entity given authority to review reports of inspection, accident investigations, and the implementation of the program is the **Health and Safety Committee**. - a) **Health and Safety Committee** - b) DOLE - c) DPWH - d) BFP ## 15. Soil Grouting Process - The process of injecting any agent into soil or rock to increase its strength or stability, protect foundations, or reduce groundwater is termed **Grouting**. - a) **Grouting** - b) Pumping - c) Bleeding - d) Screeding ## 16. Construction Safety Program Requirements - Every construction project must have a suitable **Construction Safety and Health Program**, which adheres to the rules and orders issued by the DOLE. - a) **Construction Safety and Health Program** - b) Occupational Health and Safety Program - c) Occupational Safety and Health Administration - d) Workplace Safety and Procedures ## 17. Safety Sight Distance and Vehicle Characteristics - One of the provisions for safety sight distance is dependent on the characteristics of the vehicle, including: - I. Type of vehicle (car or truck) - II. Friction between the tire and road - III. Eye height of the driver - IV. Speed of the vehicle - a) I only - b) II and III only - c) IV only - d) **All of the above** ## 18. Concrete Leveling Technique - **Screeding** is the process to level a floor or layer of concrete with a straight edge using a back and forth motion while moving across the surface. - a) Troweling - b) **Screeding** - c) Floating - d) Finishing ## 19. Structural Support Types - A structure driven into the soil to support construction by transferring building loads to a deeper and stronger layer of soil or rock is referred to as a **Pile**. - a) Caisson - b) Pier - c) Shoring - d) **Piles** ## 20. Road User Guidance Signs - **Guide signs** inform and advise road users of directions, distances, routes, and the location of services. - a) Cross road sign - b) **Guide signs** - c) Advance direction signs - d) Traffic instruction signs ## 21. Delay Concept in Transportation - The **Delay** refers to the difference between the actual travel time and the ideal travel time for a segment of the transportation system. - a) Queue time - b) Travel time - c) **Delay** - d) Service time ## 22. Construction Instructions - **Specifications** are written instructions detailing how a facility is to be constructed. - a) **Specifications** - b) Estimates - c) Bid documents - d) Plans ## 23. Tidal Wave Phases - The interval referring to the time delay in highest tide for each location due to cosmic forces and friction is called the **Age of Tides**. - a) **Age of Tides** - b) Lunar tide - c) Diurnal tide - d) Semi-diurnal tide ## 24. Road Environment Factors and Safety Sight Distance - The provision for safety sight distance is influenced by the following characteristics of the road environment: - I. Road geometry - II. Road surface - III. Road illumination at night - IV. Road topography - a) I and IV only - b) I, II, and III only - c) II and IV only - d) **All of the above** ## 25. Pavement Cracking Types - **Transverse cracking** occurs at right angles to the pavement centerline due to shrinkage or differential thermal stress of the asphalt concrete or reflective cracks. - a) Alligator cracking - b) Block cracking - c) **Transverse cracking** - d) Longitudinal cracking ## 26. Pavement Surface Wear - **Raveling** refers to the wearing away of the pavement surface caused by dislodging of aggregated particles and binder, often a result of insufficient asphalt binder in the mix. - a) Joint or crack spalling - b) Flushing - c) Bleeding - d) **Raveling** ## 27. Surveying Procedures - **Double centering** is a procedure in a horizontal angle layout that involves turning the angle twice and creating a line of sight for critical points. Not used on every point. ## 28. Fatigue Resistance Measure - **Fatigue resistance** is the measure of a material's ability to withstand cyclic (repeated) stresses, with the risk of fracture occurring without warning, even below yield strength. ## 29. Screeding Definition - **Screeding** is defined as the method of moving a straight-edge back and forth with a saw-like motion across the forms to finish concrete surfaces. ## 30. Hazard Definition - A **Hazard** is defined as a source or situation that poses a potential risk for harm, injury, or damage to health, property, or the environment. ## 31. Risk Definition - **Risk** is defined as a human action that deviates from commonly accepted safe procedures that may result in an accident; it requires adherence to a suitable Construction Safety and Health Program, per DOLE requirements. ## 32. Loading Zones - **Loading and unloading zone markings** must be red in color. ## 33. Project Definition - A **Project** is a series of activities with specified objectives that have defined start and end dates, monitored planning, and resource consumption, including money, labor, and equipment. - a) **All of the above** - b) I, II, IV, and V - c) I, II, and IV - d) I, III, and V ## 34. Contract Changes - The following reasons may cause a contract change, except for: - a) Unforeseen conditions - b) **Poor jobsite productivity** - c) A change in owner requirements - d) Designer omission or error ## 35. Road Condition Characteristics - Factors affecting safety sight distance based on the road environment include: - I. Road geometry-grade and curvature sight limitations - II. Road surface-sealed or unsealed, and its smoothness - III. Road illumination at night - IV. Road topography - a) I, II, and III only - b) **All of the above** - c) I, III, and IV only - d) II, III, and IV only ## 36. Structural Properties in Coastal Construction - Key structural properties vital for material selection in harbor and coastal construction include: - I. Specific gravity - II. Material strength - III. Resistance to cyclical impact loading - IV. Resistance to seismic forces - V. Material flexibility - VI. Structural size - a) I, II, and III only - b) IV, V only - c) I, III, and IV only - d) **All of the above** ## 37. Piling Definition - **Piles** are structural components driven into the soil transferring building loads to deeper and stronger soil or rock layers. ## 38. Trip Definition - A **Trip** is defined as the basic unit of travel behavior, involving movement from a single origin to a single destination, characterized by origins, destinations, purposes, and travel modes. ## 39. Signal Coordination - **Signal coordination** involves timing signals in relation to one another, allowing vehicles traveling at a determined speed to pass through successive green lights. ## 40. Rumble Strip Purpose - A **Rumble strip** is a type of thermoplastic lane marking that provides motorists with visual, audio, and motion warnings on the road. ## 41. Grade Resistance - **Grade resistance** represents the component of vehicle weight that acts parallel to an inclined surface. ## 42. Hazard Circumstances - **Hazard** refers to circumstances that deviate from standard conditions, permitting occurrences of accidents or incidents. ## 43. Demolition Area Restrictions - During demolition, no one except workers directly engaged in demolition shall enter an area within a distance equal to 1.5 times the height of the structure being demolished. ## 44. Logistic Definition - **Logistics** refers to the strategic management of resources, materials, and information to ensure efficient movement and delivery of goods and services. ## 45. Design Speed - **Design speed** refers to the maximum safe speed that can be maintained over a specified section of highway under favorable conditions governed by design features. ## 46. Bid Bond Valid Statement - A valid statement regarding a **bid bond** is that it represents costs incurred by the owner if the bidder fails to enter into a contract. - a) It pays for costs incurred by the bid deadline is mixed. - b) **It represents the costs that the owners incur if the bidder fails to enter into a contract.** - c) It represents costs incurred by subcontractors if the project is underbid. - d) It pays for office overhead costs related to a bid ## 47. Hygroscopic Material Definition - **Hygroscopic** refers to a substance that tends to absorb water from the air. ## 48. Safe Pile Capacity Data - The safe capacity of piles driven by powered hammers is based on data comprising: - I. Average penetration per blow (last six blows) - II. Energy of hammer - III. Weight of hammer - IV. Weight of pile including appurtenances - V. Coefficient of restitution based on pile weight - VI. **All of the above** ## 49. Berth Structure Definition - A **Pier** is a berth structure projecting out from the shoreline. - a) Groin - b) Wharf - c) Breakwater - d) **Pier** ## 50. Road Alignment Signs - **Chevron signs** are used to guide drivers through a change in the horizontal alignment of the road. - a) **Chevron signs** - b) Supplementary signs - c) Guide post signs - d) Delineators ## 51. Road Delineation Devices - Delineation of road alignment includes: - I. Pavement Markings - II. Signs - III. Guide Posts - IV. Reflective delineators - V. Lighting - VI. Curb or other physical devices - a) I, II, II, and IV only - b) I, II, IV, and VI only - c) I, V, V, and VI only - d) **All of the above** ## 52. Properties of Queuing Diagrams - Important properties in queuing diagrams include: - I. The slope of D(t) is the departure rate; the slope of A(t) is the arrival rate. - II. The departure rate cannot exceed the service rate or capacity of the server. It may be less. - III. Cumulative departures can never exceed cumulative arrivals. D(t) can never be above A(t) in the queuing diagram. - IV. When a queue exists, the departure rate equals the service rate. In the absence of a queue, the same rate equals the arrival rate. - V. **All of the above** ## 53. Scaffolding Capacity Brackets - Capacity requirements for all scaffolding must be: - a) At least four times its own weight - b) At least 6 times its own weight - c) At most 6 times its own weight - d) At most 5 times its own weight ## 54. Highway Driver Elements - The essential elements of highway driving are referred to as **Driving Task**, encompassing navigation, guidance, and control. - a) **Driving task** - b) Ergonomics - c) Engineering psychology - d) Range index ## 55. Protective Systems in Excavation - **Protective systems** include methods for protecting workers from cave-ins during excavations, consisting of support systems, sloping, benching systems, and shield systems. - a) **Protective system** - b) Personnel protective system - c) Fall arrest system - d) Level arrest system ## 56. Bucket Volume Definitions - **Bucket load capacity** refers to the volume contained within the bucket outline as determined by the bucket sides. - a) Plate line capacity - b) Water line capacity - c) Heap volume - d) **Bucket load capacity** ## 57. Contract Definition - A **Contract** is defined as a formal or legally binding agreement between two parties. ## 58. Toolbox Meeting Definition - A **Toolbox Meeting** is an informal group discussion that focuses on a specific safety issue, facilitating health and safety culture discussions on job sites. ## 59. Road User Directional Signs - **Guide signs** inform road users about the directions and distances to destinations on their route or intersecting roads. - a) Supplementary signs - b) **Guide signs** - c) Warning signs - d) Stack signs ## 60. Specifications Definition - **Specifications** provide detailed requirements for materials, equipment, and workmanship for projects. - a) **Specifications** - b) Bid documents - c) Estimates - d) Plans ## 61. Damping Capacity - **Damping capacity** is the measure of a material’s ability to absorb or dissipate mechanical vibrations. ## 62. Profile Drawing Definition - A **Profile** is a drawing with elevation as the vertical axis and horizontal distance measured along the centerline as the horizontal axis. ## 63. PERT CPM Network Preparation - When preparing a report on the PERT CPM network in construction, one should consider: - a) Pessimistic time network - b) Optimistic time - c) Probable time - d) **All of the above** ## 64. Post-Construction Resolution - This occurs after completion of construction and the resolution of the majority of punchlist and commissioning issues, known as the **Profile**. ## 65. Concrete Formwork Concept - **Formwork** is necessary for concrete placement to maintain shape before the concrete sets. ## 66. Benching Technique in Excavation - **Benching** is a method of protecting workers from cave-ins by creating a series of horizontal levels or steps in excavated areas. - a) **Benching** - b) Shoring - c) Shielding - d) Fall arrest system ## 67. Concrete Surface Leveling - The process of leveling a concrete surface with enough mortar after screeding is termed **Floating**. - a) **Floating** - b) Edging - c) Leveling - d) Bleeding ## 68. Control Joint Placement in Concrete - **Jointing** involves placing premolded inserts in concrete slabs to control cracking due to shrinkage, immediately after or during edging. - a) Jointing - b) Troweling - c) Leveling - d) Edging ## 69. Safety Barrier Considerations - Reasons to establish a need for safety barriers include: - I. Fore slope and back slope steepness and height - II. Unforgiving hazards within the clear zone - III. Water hazards within the clear zone - a) II only - b) I only - c) II and III only - d) **All of the three** ## 70. Limits on Road Messages - Messages painted on pavement should be limited to **six words or less**. - a) **six words or less** - b) five words or less - c) four words or less - d) three words or less ## 71. Types of Pavement Markings - The four types of pavement and curb markings include: - a) **longitudinal lines, transverse lines, lane lines, and center lines** - b) longitudinal lines, transverse lines, stop lines, & center lines - c) longitudinal lines, transverse lines, transition lines, & stop lines - d) longitudinal lines, transverse lines, other lines, & other markings ## 72. Overtaking Lane Design Considerations - Design considerations for overtaking and climbing lanes include: - I. Initial diverge taper - II. Auxiliary lane length - III. End or merge taper - a) **I, II, & III** - b) I & II only - c) II & III only - d) I & III only ## 73. Road Density Definition - **Density** is defined as the number of vehicles per unit distance occupying a roadway section at a given instant in time, measured in vehicles per mile or kilometer. - a) flow - b) **density** - c) capacity - d) volume ## 74. Continuous Waterfront Structure - A **Wharf** is a continuous structure built parallel to the shoreline for loading and unloading ships. - a) pier - b) **wharf** - c) port - d) lighthouse ## 75. Vertical Design Factors - The minimum **K value** for sag vertical should be based on the following factors: - I. Safety sight distance for drivers - II. Appearance in low fill and flat areas - III. Riding comfort, especially at floodway approaches - IV. Vertical alignment fitting into natural terrain. - a) I, II, & III only - b) I, III, & IV only - c) I, II, & IV only - d) II, III, & IV only ## 76. Rumble Strip Definition - A **Rumble strip** is a thermoplastic lane marking designed for visual, audio, and motion warnings for motorists on the road. - a) regulatory signs - b) diagonal marking - c) chevron marking - d) **rumble strip** ## 77. Lane Line Continuation Rules - Lane lines must not be continued in the following scenarios: - I. Across signalized intersections, where low priority road lines must be discontinued. - II. Across side street entrances, except for one-way streets. - III. Past the start of the taper at multi-lane road narrows. - IV. On roads with more than two lanes without median islands. - a) I, II, & IV - b). I, II, & IV - c) II, III, & IV - d) I, II, and III ## 78. Directional Information Signs - **Guide signs** serve to inform road users about directions, distances to destinations, and service locations. - a) **guide signs** - b) warning signs - c) regulatory sign - d) traffic sign ## 79. Benefits of Shoulder Paving - **Shoulder paving** offers: - I. Integrity of the pavement - II. Width for edge line pavement markings - III. Enhanced safety to prevent vehicle skidding - IV. Lower maintenance costs compared to paved shoulders - a) I, III, & IV only - b) **all of the above** - c) I, II, & III only - d) II, III, & IV only ## 80. Structures Built into the Sea - A **Pier** is defined as a structure built into the sea but not aligned parallel to the coastline, which serves various purposes for vessels. - a) lighthouse - b) port - c) **pier** - d) wharf ## 81. Navigable Water Definitions - A navigable body of water leading to a harbor is referred to as a **Channel**. - a) fairway - b) **channel** - c) shoal - d) significant depth ## 82. Types of Curves in Roads - **Vertical curves** are typically parabolas centered around the point of intersection of vertical tangents they connect. - a) **vertical curve** - b) vertical tangent - c) spiral curve - d) grade ## 83. Wind-Generated Waves - Waves under wind influence are referred to as **Sea waves**. - A. Wakes - B. **Sea** - C. Swells - D. Seiching ## 84. Traffic Flow Rate - The **Capacity** refers to the maximum sustained rate of flow for vehicles (passenger cars per hour per lane) under uniform conditions on a freeway segment. - A. Density - B. Traffic flow - C. **Capacity** - D. Design hourly volume ## 85. Hazardous Condition Warnings - **Warning signs** inform road users about hazardous or unexpected road conditions. - A. Roadwork signs - B. **Warning signs** - C. Traffic signs - D. Guide signs ## 86. Purpose of Edge Lines - The purpose of **edge lines** includes discouraging shoulder travel, enhancing safety at night, guiding past hazards, and delineating the edge of the traveled way from the shoulder. - A. I - B. IV - C. V - D. II ## 87. Road Capacity Measurement - **Road capacity** is the maximum number of vehicles expected to pass over a given section of a roadway in one direction during one hour. - A. **Road capacity** - B. Flow of traffic - C. Density - D. Free flow ## 88. High-Rise Building Cleaners - For window cleaners of high-rise buildings, **Slung Scaffold** is most appropriate for providing a suspended working platform. - a) Birdcage Scaffold - b) **Slung Scaffold** - c) Cantilever Scaffold - d) Trestle Scaffold ## 89. Leading Workplace Fatalities - **Falls** are the leading cause accounting for more than 50% of workplace fatalities. - a) Slips - b) Trips - c) **Falls** - d) Electrocution ## 90. Excavation Material Placement - Excavated material should be kept from the excavation edge at a distance not less than **1/4** of the excavation depth. - a) **1/4** - b) 1/3 - c) 1/2 - d) 2/3 ## 91. Temporary Vertical Support Definition - **Dead Shore** refers to temporary vertical support installed directly beneath structural elements while repairs or foundation work is conducted. - A. **Dead Shore** - B. Lateral Bracing - C. Cantilever Prop - D. Raking Shore ## 92. Building Information Modeling - **Building Information Modeling** (BIM) is a 3D model-driven process generating a digital representation of facility features, supporting informed decision-making throughout its lifecycle. - A. CAD Drafting - B. **Building Information Modeling** - C. GIS Mapping - D. Structural Analysis Software ## 93. Operating Costs in Contracting - **Operating Cost** refers to expenses incurred while using equipment for project execution, including repair costs, parts replacement, fuels, labor, and storage. - A. I, II, III, IV - B. I, II, III, IV, V - C. I, II, III - D. II, III, IV ## 94. Water Supply Pipe Terminology - In a water supply system, the vertical pipes are referred to as **risers**, and the horizontal pipes as **branches**. - A. branches and risers respectively - B. **risers and branches respectively** - C. roughing ins and connections respectively - D. connections and roughing ins respectively ## 95. Joint Sealant Definition - A **Joint Sealant** is a rubber or rubber-like material used to fill and seal joints or openings, either alone or with other materials. - A. Grout - B. **Joint Sealant** - C. Adhesive - D. Mortar ## 96. Demolition Area Entry Restriction - During demolition, no one except those engaged in the work shall enter an area within a distance of **1.5 times the height** of the structure being demolished. - A. 1.2 times the height of the structure - B. 2.0 times the height of the structure - C. **1.5 times the height of the structure** - D. 3.0 times the height of the structure ## 97. Vertical Pipe Definition - A **Riser** is a vertical pipe used to transport fluids between different floors of a building. - A. Drain - B. Conduit - C. **Riser** - D. Vent ## 98. Plan View Definition - A **Plan View** is a scaled drawing representing the layout of a structure as seen from above, detailing the arrangement of spaces, walls, and features. - A. **Plan View** - B. Section View - C. Isometric View - D. Elevation View ## 99. Corrosion-Resistant Coating - **Epoxy** is a common protective coating for enhancing corrosion resistance and durability of pipes and appliances. - A. **Epoxy** - B. Latex - C. Polyurethane - D. Acrylic ## 100. Surveying Type Acknowledgment - **Geodetic Surveying** is the type of surveying that takes the curvature of the Earth into account. - A. **Geodetic Surveying** - B. Plane Surveying - C. Topographic Surveying - D. Hydrographic Surveying ## 101. Competency Standards Defined - **Competency Standards** define the required skills, knowledge, and attitudes necessary for effective job performance in the workplace. - A. Work Ethics - B. **Competency Standards** - C. Training Manuals - D. Job Description ## 102. Concrete Retarder Example - A commonly used chemical compound as a retarder in concrete is **Calcium lignosulphonate**. - A. Calcium chloride - B. Aluminum powder - C. Potassium carbonate - D. **Calcium lignosulphonate** ## 103. Sub-base Thickness Determination - The minimum thickness for one layer of compacted granular sub-base should be **20 cm**. - A. 10 cm - B. **20 cm** - C. 15 cm - D. 12 cm ## 104. Hazard Control Classification - The type of hazard control that involves replacing a toxic or hazardous material with a less harmful one is termed **Substitution**. - A. **Substitution** - B. Elimination - C. Engineering Control - D. Administrative Control ## 2. Substitution - B. Elimination - C. Engineering Control - D. Administrative Control ## 2. Substitution - B. Elimination - C. Engineering Control - D. Administrative Control

Iceberg demonstrates the relationship between direct and indirect costs of accidents, showing that on average, indirect costs exceed direct costs. Examples of indirect costs include: - a) Overhead costs - b) Schedule delays - c) **Medical costs** (DIRECT COST) - d) Cleanup time ## 7. Geometric Sequences - **Sequence Identification:** The proper arrangement of the following shapes by their complexity is: I. Quadrilateral II. Parallelogram III. Rectangle IV. Square. - a) II, IV, III, I - b) I, II, III, IV - c) IV, III, II, I - d) I, III, II, IV ## 8. Building Use Classification - The term **Occupancy** refers to a type of use of a building for interior space such as an office, restaurant, private residence, or school, grouped based on similar life-safety characteristics, fire hazards, and combustible contents. - a) Building elements - b) **Occupancy** - c) Building Code - d) Accommodation ## 9. Construction Pit Transport Fees - The maximum distance, as specified in the construction contract, which the contractor is expected to transport soil material without receiving additional payment, is known as **Freehaul distance**. - a) **Freehaul distance** - b) Overhaul distance - c) Haul distance - d) Baseline distance ## 10. Retarder Application Principles - **Fundamental Principles for Upper Retarders:** The retarder should be as near as possible to the warm side of the insulation or the warm face of the assembly. Moreover, it should be installed using a method appropriate for the specific condensation hazard. ## 11. Material Characteristics - **Hardness**: A measure of a material's ability to resist indentation or penetration. - a) **Hardness** - b) Ductility - c) Toughness - d) Resilience ## 12. Soil Density Changes - **Consolidation**: An increase in the soil density of cohesive soil resulting from the expulsion of water from the soil's void spaces. - a) Segregation - b) **Consolidation** - c) Compaction - d) Soil Stabilization ## 13. Concrete Finishing Process - The correct step-by-step process of finishing standard weight concrete slabs is as follows: 1. Bleeding 2. Screeding 3. Leveling 4. Edging 5. Jointing 6. Floating 7. Troweling 8. Broom finishing ## 14. Safety Oversight Authority - The entity given authority to review reports of inspection, accident investigations, and the implementation of the program is the **Health and Safety Committee**. - a) **Health and Safety Committee** - b) DOLE - c) DPWH - d) BFP ## 15. Soil Grouting Process - The process of injecting any agent into soil or rock to increase its strength or stability, protect foundations, or reduce groundwater is termed **Grouting**. - a) **Grouting** - b) Pumping - c) Bleeding - d) Screeding ## 16. Construction Safety Program Requirements - Every construction project must have a suitable **Construction Safety and Health Program**, which adheres to the rules and orders issued by the DOLE. - a) **Construction Safety and Health Program** - b) Occupational Health and Safety Program - c) Occupational Safety and Health Administration - d) Workplace Safety and Procedures ## 17. Safety Sight Distance and Vehicle Characteristics - One of the provisions for safety sight distance is dependent on the characteristics of the vehicle, including: - I. Type of vehicle (car or truck) - II. Friction between the tire and road - III. Eye height of the driver - IV. Speed of the vehicle - a) I only - b) II and III only - c) IV only - d) **All of the above** ## 18. Concrete Leveling Technique - **Screeding** is the process to level a floor or layer of concrete with a straight edge using a back and forth motion while moving across the surface. - a) Troweling - b) **Screeding** - c) Floating - d) Finishing ## 19. Structural Support Types - A structure driven into the soil to support construction by transferring building loads to a deeper and stronger layer of soil or rock is referred to as a **Pile**. - a) Caisson - b) Pier - c) Shoring - d) **Piles** ## 20. Road User Guidance Signs - **Guide signs** inform and advise road users of directions, distances, routes, and the location of services. - a) Cross road sign - b) **Guide signs** - c) Advance direction signs - d) Traffic instruction signs ## 21. Delay Concept in Transportation - The **Delay** refers to the difference between the actual travel time and the ideal travel time for a segment of the transportation system. - a) Queue time - b) Travel time - c) **Delay** - d) Service time ## 22. Construction Instructions - **Specifications** are written instructions detailing how a facility is to be constructed. - a) **Specifications** - b) Estimates - c) Bid documents - d) Plans ## 23. Tidal Wave Phases - The interval referring to the time delay in highest tide for each location due to cosmic forces and friction is called the **Age of Tides**. - a) **Age of Tides** - b) Lunar tide - c) Diurnal tide - d) Semi-diurnal tide ## 24. Road Environment Factors and Safety Sight Distance - The provision for safety sight distance is influenced by the following characteristics of the road environment: - I. Road geometry - II. Road surface - III. Road illumination at night - IV. Road topography - a) I and IV only - b) I, II, and III only - c) II and IV only - d) **All of the above** ## 25. Pavement Cracking Types - **Transverse cracking** occurs at right angles to the pavement centerline due to shrinkage or differential thermal stress of the asphalt concrete or reflective cracks. - a) Alligator cracking - b) Block cracking - c) **Transverse cracking** - d) Longitudinal cracking ## 26. Pavement Surface Wear - **Raveling** refers to the wearing away of the pavement surface caused by dislodging of aggregated particles and binder, often a result of insufficient asphalt binder in the mix. - a) Joint or crack spalling - b) Flushing - c) Bleeding - d) **Raveling** ## 27. Surveying Procedures - **Double centering** is a procedure in a horizontal angle layout that involves turning the angle twice and creating a line of sight for critical points. Not used on every point. ## 28. Fatigue Resistance Measure - **Fatigue resistance** is the measure of a material's ability to withstand cyclic (repeated) stresses, with the risk of fracture occurring without warning, even below yield strength. ## 29. Screeding Definition - **Screeding** is defined as the method of moving a straight-edge back and forth with a saw-like motion across the forms to finish concrete surfaces. ## 30. Hazard Definition - A **Hazard** is defined as a source or situation that poses a potential risk for harm, injury, or damage to health, property, or the environment. ## 31. Risk Definition - **Risk** is defined as a human action that deviates from commonly accepted safe procedures that may result in an accident; it requires adherence to a suitable Construction Safety and Health Program, per DOLE requirements. ## 32. Loading Zones - **Loading and unloading zone markings** must be red in color. ## 33. Project Definition - A **Project** is a series of activities with specified objectives that have defined start and end dates, monitored planning, and resource consumption, including money, labor, and equipment. - a) **All of the above** - b) I, II, IV, and V - c) I, II, and IV - d) I, III, and V ## 34. Contract Changes - The following reasons may cause a contract change, except for: - a) Unforeseen conditions - b) **Poor jobsite productivity** - c) A change in owner requirements - d) Designer omission or error ## 35. Road Condition Characteristics - Factors affecting safety sight distance based on the road environment include: - I. Road geometry-grade and curvature sight limitations - II. Road surface-sealed or unsealed, and its smoothness - III. Road illumination at night - IV. Road topography - a) I, II, and III only - b) **All of the above** - c) I, III, and IV only - d) II, III, and IV only ## 36. Structural Properties in Coastal Construction - Key structural properties vital for material selection in harbor and coastal construction include: - I. Specific gravity - II. Material strength - III. Resistance to cyclical impact loading - IV. Resistance to seismic forces - V. Material flexibility - VI. Structural size - a) I, II, and III only - b) IV, V only - c) I, III, and IV only - d) **All of the above** ## 37. Piling Definition - **Piles** are structural components driven into the soil transferring building loads to deeper and stronger soil or rock layers. ## 38. Trip Definition - A **Trip** is defined as the basic unit of travel behavior, involving movement from a single origin to a single destination, characterized by origins, destinations, purposes, and travel modes. ## 39. Signal Coordination - **Signal coordination** involves timing signals in relation to one another, allowing vehicles traveling at a determined speed to pass through successive green lights. ## 40. Rumble Strip Purpose - A **Rumble strip** is a type of thermoplastic lane marking that provides motorists with visual, audio, and motion warnings on the road. ## 41. Grade Resistance - **Grade resistance** represents the component of vehicle weight that acts parallel to an inclined surface. ## 42. Hazard Circumstances - **Hazard** refers to circumstances that deviate from standard conditions, permitting occurrences of accidents or incidents. ## 43. Demolition Area Restrictions - During demolition, no one except workers directly engaged in demolition shall enter an area within a distance equal to 1.5 times the height of the structure being demolished. ## 44. Logistic Definition - **Logistics** refers to the strategic management of resources, materials, and information to ensure efficient movement and delivery of goods and services. ## 45. Design Speed - **Design speed** refers to the maximum safe speed that can be maintained over a specified section of highway under favorable conditions governed by design features. ## 46. Bid Bond Valid Statement - A valid statement regarding a **bid bond** is that it represents costs incurred by the owner if the bidder fails to enter into a contract. - a) It pays for costs incurred by the bid deadline is mixed. - b) **It represents the costs that the owners incur if the bidder fails to enter into a contract.** - c) It represents costs incurred by subcontractors if the project is underbid. - d) It pays for office overhead costs related to a bid ## 47. Hygroscopic Material Definition - **Hygroscopic** refers to a substance that tends to absorb water from the air. ## 48. Safe Pile Capacity Data - The safe capacity of piles driven by powered hammers is based on data comprising: - I. Average penetration per blow (last six blows) - II. Energy of hammer - III. Weight of hammer - IV. Weight of pile including appurtenances - V. Coefficient of restitution based on pile weight - VI. **All of the above** ## 49. Berth Structure Definition - A **Pier** is a berth structure projecting out from the shoreline. - a) Groin - b) Wharf - c) Breakwater - d) **Pier** ## 50. Road Alignment Signs - **Chevron signs** are used to guide drivers through a change in the horizontal alignment of the road. - a) **Chevron signs** - b) Supplementary signs - c) Guide post signs - d) Delineators ## 51. Road Delineation Devices - Delineation of road alignment includes: - I. Pavement Markings - II. Signs - III. Guide Posts - IV. Reflective delineators - V. Lighting - VI. Curb or other physical devices - a) I, II, II, and IV only - b) I, II, IV, and VI only - c) I, V, V, and VI only - d) **All of the above** ## 52. Properties of Queuing Diagrams - Important properties in queuing diagrams include: - I. The slope of D(t) is the departure rate; the slope of A(t) is the arrival rate. - II. The departure rate cannot exceed the service rate or capacity of the server. It may be less. - III. Cumulative departures can never exceed cumulative arrivals. D(t) can never be above A(t) in the queuing diagram. - IV. When a queue exists, the departure rate equals the service rate. In the absence of a queue, the same rate equals the arrival rate. - V. **All of the above** ## 53. Scaffolding Capacity Brackets - Capacity requirements for all scaffolding must be: - a) At least four times its own weight - b) At least 6 times its own weight - c) At most 6 times its own weight - d) At most 5 times its own weight ## 54. Highway Driver Elements - The essential elements of highway driving are referred to as **Driving Task**, encompassing navigation, guidance, and control. - a) **Driving task** - b) Ergonomics - c) Engineering psychology - d) Range index ## 55. Protective Systems in Excavation - **Protective systems** include methods for protecting workers from cave-ins during excavations, consisting of support systems, sloping, benching systems, and shield systems. - a) **Protective system** - b) Personnel protective system - c) Fall arrest system - d) Level arrest system ## 56. Bucket Volume Definitions - **Bucket load capacity** refers to the volume contained within the bucket outline as determined by the bucket sides. - a) Plate line capacity - b) Water line capacity - c) Heap volume - d) **Bucket load capacity** ## 57. Contract Definition - A **Contract** is defined as a formal or legally binding agreement between two parties. ## 58. Toolbox Meeting Definition - A **Toolbox Meeting** is an informal group discussion that focuses on a specific safety issue, facilitating health and safety culture discussions on job sites. ## 59. Road User Directional Signs - **Guide signs** inform road users about the directions and distances to destinations on their route or intersecting roads. - a) Supplementary signs - b) **Guide signs** - c) Warning signs - d) Stack signs ## 60. Specifications Definition - **Specifications** provide detailed requirements for materials, equipment, and workmanship for projects. - a) **Specifications** - b) Bid documents - c) Estimates - d) Plans ## 61. Damping Capacity - **Damping capacity** is the measure of a material’s ability to absorb or dissipate mechanical vibrations. ## 62. Profile Drawing Definition - A **Profile** is a drawing with elevation as the vertical axis and horizontal distance measured along the centerline as the horizontal axis. ## 63. PERT CPM Network Preparation - When preparing a report on the PERT CPM network in construction, one should consider: - a) Pessimistic time network - b) Optimistic time - c) Probable time - d) **All of the above** ## 64. Post-Construction Resolution - This occurs after completion of construction and the resolution of the majority of punchlist and commissioning issues, known as the **Profile**. ## 65. Concrete Formwork Concept - **Formwork** is necessary for concrete placement to maintain shape before the concrete sets. ## 66. Benching Technique in Excavation - **Benching** is a method of protecting workers from cave-ins by creating a series of horizontal levels or steps in excavated areas. - a) **Benching** - b) Shoring - c) Shielding - d) Fall arrest system ## 67. Concrete Surface Leveling - The process of leveling a concrete surface with enough mortar after screeding is termed **Floating**. - a) **Floating** - b) Edging - c) Leveling - d) Bleeding ## 68. Control Joint Placement in Concrete - **Jointing** involves placing premolded inserts in concrete slabs to control cracking due to shrinkage, immediately after or during edging. - a) Jointing - b) Troweling - c) Leveling - d) Edging ## 69. Safety Barrier Considerations - Reasons to establish a need for safety barriers include: - I. Fore slope and back slope steepness and height - II. Unforgiving hazards within the clear zone - III. Water hazards within the clear zone - a) II only - b) I only - c) II and III only - d) **All of the three** ## 70. Limits on Road Messages - Messages painted on pavement should be limited to **six words or less**. - a) **six words or less** - b) five words or less - c) four words or less - d) three words or less ## 71. Types of Pavement Markings - The four types of pavement and curb markings include: - a) **longitudinal lines, transverse lines, lane lines, and center lines** - b) longitudinal lines, transverse lines, stop lines, & center lines - c) longitudinal lines, transverse lines, transition lines, & stop lines - d) longitudinal lines, transverse lines, other lines, & other markings ## 72. Overtaking Lane Design Considerations - Design considerations for overtaking and climbing lanes include: - I. Initial diverge taper - II. Auxiliary lane length - III. End or merge taper - a) **I, II, & III** - b) I & II only - c) II & III only - d) I & III only ## 73. Road Density Definition - **Density** is defined as the number of vehicles per unit distance occupying a roadway section at a given instant in time, measured in vehicles per mile or kilometer. - a) flow - b) **density** - c) capacity - d) volume ## 74. Continuous Waterfront Structure - A **Wharf** is a continuous structure built parallel to the shoreline for loading and unloading ships. - a) pier - b) **wharf** - c) port - d) lighthouse ## 75. Vertical Design Factors - The minimum **K value** for sag vertical should be based on the following factors: - I. Safety sight distance for drivers - II. Appearance in low fill and flat areas - III. Riding comfort, especially at floodway approaches - IV. Vertical alignment fitting into natural terrain. - a) I, II, & III only - b) I, III, & IV only - c) I, II, & IV only - d) II, III, & IV only ## 76. Rumble Strip Definition - A **Rumble strip** is a thermoplastic lane marking designed for visual, audio, and motion warnings for motorists on the road. - a) regulatory signs - b) diagonal marking - c) chevron marking - d) **rumble strip** ## 77. Lane Line Continuation Rules - Lane lines must not be continued in the following scenarios: - I. Across signalized intersections, where low priority road lines must be discontinued. - II. Across side street entrances, except for one-way streets. - III. Past the start of the taper at multi-lane road narrows. - IV. On roads with more than two lanes without median islands. - a) I, II, & IV - b). I, II, & IV - c) II, III, & IV - d) I, II, and III ## 78. Directional Information Signs - **Guide signs** serve to inform road users about directions, distances to destinations, and service locations. - a) **guide signs** - b) warning signs - c) regulatory sign - d) traffic sign ## 79. Benefits of Shoulder Paving - **Shoulder paving** offers: - I. Integrity of the pavement - II. Width for edge line pavement markings - III. Enhanced safety to prevent vehicle skidding - IV. Lower maintenance costs compared to paved shoulders - a) I, III, & IV only - b) **all of the above** - c) I, II, & III only - d) II, III, & IV only ## 80. Structures Built into the Sea - A **Pier** is defined as a structure built into the sea but not aligned parallel to the coastline, which serves various purposes for vessels. - a) lighthouse - b) port - c) **pier** - d) wharf ## 81. Navigable Water Definitions - A navigable body of water leading to a harbor is referred to as a **Channel**. - a) fairway - b) **channel** - c) shoal - d) significant depth ## 82. Types of Curves in Roads - **Vertical curves** are typically parabolas centered around the point of intersection of vertical tangents they connect. - a) **vertical curve** - b) vertical tangent - c) spiral curve - d) grade ## 83. Wind-Generated Waves - Waves under wind influence are referred to as **Sea waves**. - A. Wakes - B. **Sea** - C. Swells - D. Seiching ## 84. Traffic Flow Rate - The **Capacity** refers to the maximum sustained rate of flow for vehicles (passenger cars per hour per lane) under uniform conditions on a freeway segment. - A. Density - B. Traffic flow - C. **Capacity** - D. Design hourly volume ## 85. Hazardous Condition Warnings - **Warning signs** inform road users about hazardous or unexpected road conditions. - A. Roadwork signs - B. **Warning signs** - C. Traffic signs - D. Guide signs ## 86. Purpose of Edge Lines - The purpose of **edge lines** includes discouraging shoulder travel, enhancing safety at night, guiding past hazards, and delineating the edge of the traveled way from the shoulder. - A. I - B. IV - C. V - D. II ## 87. Road Capacity Measurement - **Road capacity** is the maximum number of vehicles expected to pass over a given section of a roadway in one direction during one hour. - A. **Road capacity** - B. Flow of traffic - C. Density - D. Free flow ## 88. High-Rise Building Cleaners - For window cleaners of high-rise buildings, **Slung Scaffold** is most appropriate for providing a suspended working platform. - a) Birdcage Scaffold - b) **Slung Scaffold** - c) Cantilever Scaffold - d) Trestle Scaffold ## 89. Leading Workplace Fatalities - **Falls** are the leading cause accounting for more than 50% of workplace fatalities. - a) Slips - b) Trips - c) **Falls** - d) Electrocution ## 90. Excavation Material Placement - Excavated material should be kept from the excavation edge at a distance not less than **1/4** of the excavation depth. - a) **1/4** - b) 1/3 - c) 1/2 - d) 2/3 ## 91. Temporary Vertical Support Definition - **Dead Shore** refers to temporary vertical support installed directly beneath structural elements while repairs or foundation work is conducted. - A. **Dead Shore** - B. Lateral Bracing - C. Cantilever Prop - D. Raking Shore ## 92. Building Information Modeling - **Building Information Modeling** (BIM) is a 3D model-driven process generating a digital representation of facility features, supporting informed decision-making throughout its lifecycle. - A. CAD Drafting - B. **Building Information Modeling** - C. GIS Mapping - D. Structural Analysis Software ## 93. Operating Costs in Contracting - **Operating Cost** refers to expenses incurred while using equipment for project execution, including repair costs, parts replacement, fuels, labor, and storage. - A. I, II, III, IV - B. I, II, III, IV, V - C. I, II, III - D. II, III, IV ## 94. Water Supply Pipe Terminology - In a water supply system, the vertical pipes are referred to as **risers**, and the horizontal pipes as **branches**. - A. branches and risers respectively - B. **risers and branches respectively** - C. roughing ins and connections respectively - D. connections and roughing ins respectively ## 95. Joint Sealant Definition - A **Joint Sealant** is a rubber or rubber-like material used to fill and seal joints or openings, either alone or with other materials. - A. Grout - B. **Joint Sealant** - C. Adhesive - D. Mortar ## 96. Demolition Area Entry Restriction - During demolition, no one except those engaged in the work shall enter an area within a distance of **1.5 times the height** of the structure being demolished. - A. 1.2 times the height of the structure - B. 2.0 times the height of the structure - C. **1.5 times the height of the structure** - D. 3.0 times the height of the structure ## 97. Vertical Pipe Definition - A **Riser** is a vertical pipe used to transport fluids between different floors of a building. - A. Drain - B. Conduit - C. **Riser** - D. Vent ## 98. Plan View Definition - A **Plan View** is a scaled drawing representing the layout of a structure as seen from above, detailing the arrangement of spaces, walls, and features. - A. **Plan View** - B. Section View - C. Isometric View - D. Elevation View ## 99. Corrosion-Resistant Coating - **Epoxy** is a common protective coating for enhancing corrosion resistance and durability of pipes and appliances. - A. **Epoxy** - B. Latex - C. Polyurethane - D. Acrylic ## 100. Surveying Type Acknowledgment - **Geodetic Surveying** is the type of surveying that takes the curvature of the Earth into account. - A. **Geodetic Surveying** - B. Plane Surveying - C. Topographic Surveying - D. Hydrographic Surveying ## 101. Competency Standards Defined - **Competency Standards** define the required skills, knowledge, and attitudes necessary for effective job performance in the workplace. - A. Work Ethics - B. **Competency Standards** - C. Training Manuals - D. Job Description ## 102. Concrete Retarder Example - A commonly used chemical compound as a retarder in concrete is **Calcium lignosulphonate**. - A. Calcium chloride - B. Aluminum powder - C. Potassium carbonate - D. **Calcium lignosulphonate** ## 103. Sub-base Thickness Determination - The minimum thickness for one layer of compacted granular sub-base should be **20 cm**. - A. 10 cm - B. **20 cm** - C. 15 cm - D. 12 cm ## 104. Hazard Control Classification - The type of hazard control that involves replacing a toxic or hazardous material with a less harmful one is termed **Substitution**. - A. **Substitution** - B. Elimination - C. Engineering Control - D. Administrative Control ## 2. Substitution - B. Elimination - C. Engineering Control - D. Administrative Control ## 2. Substitution - B. Elimination - C. Engineering Control - D. Administrative Control

Operative Lecture 8: Polymerization Shrinkage

Operative Lecture 8: Polymerization Shrinkage

Lecture 4: Shrinkage Methods

L5: Subset selection and shrinkage methods

Algebra 2: Unit 2 (Translations, Stretches & Shrinks)

Shrinkage Methods

Ancient world Unit 6 Shrinking the Afro-Eurasian World Master Quizlet

(Shrinked) Chapter 3 Test Chem

Creep, relaxation and shrinkage

📘 Chapter 19: Blood – Full Simplified Study Notes (27 Slides) ⸻ Slide 1: Cardiovascular System • Cardiovascular system = heart, blood, blood vessels. • Blood’s job: • Delivers nutrients, hormones, oxygen, and chemical messages. • Carries immune cells to fight infections. • Why it matters: Without this transport system, cells would starve and toxins would build up. • Analogy: Like UPS + garbage service → delivers packages (nutrients, O₂) and removes trash (waste, CO₂). ⸻ Slide 2: Whole Blood • Whole blood = plasma + formed elements. • Hematocrit: percentage of blood volume made of cells. • Plasma: watery fluid. • Key properties of blood: • Temp: 38°C (100.4°F) → warmer than body surface. • Thickness: 5x thicker than water. • pH: ~7.4 (slightly alkaline). • Volume: Men = 5–6 L, Women = 4–5 L. • About 7% of body weight. • Example: If someone weighs 150 lbs, about 10 lbs of that is blood. ⸻ Slide 3: Blood Plasma • Plasma = liquid with proteins + solutes. • Proteins: • Albumins: keep water inside blood vessels (prevent swelling). • Globulins: antibodies → defense. • Fibrinogen: forms clots. • Other solutes: • Electrolytes: Na⁺, K⁺, Cl⁻, HCO₃⁻ (important for nerves/muscles). • Nutrients: glucose, fructose, amino acids. • Wastes: urea, uric acid. • Analogy: Plasma = soup broth carrying salt, sugar, proteins, and waste. ⸻ Slide 4: Formed Elements • Red Blood Cells (RBCs / erythrocytes): 99.9% of all blood cells. • RBC count: Men = 4.5–6.3 million/μL, Women = 4.2–5.5 million/μL. • Platelets: fragments needed for clotting. • White Blood Cells (WBCs / leukocytes): fight disease. • Think: Plasma is the liquid, formed elements are the “stuff floating inside.” ⸻ Slide 5: RBC Structure • RBCs lose their nucleus & organelles. • Consequences: • Can’t divide. • Can’t make proteins or repair. • Only use glycolysis (anaerobic metabolism) → no oxygen needed for energy. • Analogy: Like delivery trucks with no engine shop → they drive until they break down. ⸻ Slide 6: RBC Lifespan • RBCs have no nucleus, mitochondria, ribosomes → no repair. • Rely on glycolysis for energy. • Live about 120 days. • Must be recycled by spleen/liver. • Example: Like a disposable battery that runs until it dies. ⸻ Slide 7: RBC Shape & Function • Shape = biconcave disc (doughnut-like, thin middle). • Benefits: • High surface area → better oxygen exchange. • Can stack like coins → smooth flow. • Flexible → squeeze through tiny capillaries. • Analogy: Like a flexible frisbee that can bend and stack. ⸻ Slide 8: Hemoglobin • Main protein inside RBC. • Structure: • 2 alpha chains + 2 beta chains. • Each has heme group with iron atom (Fe). • Function: Iron binds oxygen → carries it around body. • Why recycle? Iron is valuable, so old RBCs get broken down to save it. • Analogy: Hemoglobin = oxygen backpack. ⸻ Slide 9: RBC Lifecycle • Starts from hemocytoblast (stem cell). • Branches into: • Myeloid stem cells: make RBCs + some WBCs. • Lymphoid stem cells: make lymphocytes. • Think: Hemocytoblast = tree trunk, RBCs and WBCs = branches. ⸻ Slide 10: RBC Production (Erythropoiesis) • Erythropoiesis = making RBCs. • Embryo: 1st 8 weeks = yolk sac → later liver, spleen, thymus, bone marrow. • Adult: red bone marrow only (vertebrae, sternum, ribs, skull, pelvis, ends of long bones). • Nutrients needed: amino acids, iron, vitamins B12, B6, folic acid. • Analogy: RBCs = cookies, bone marrow = kitchen, iron + vitamins = ingredients. ⸻ Slide 11: RBC Production Control • Controlled by erythropoietin (EPO). • Made by kidneys/liver when low oxygen (hypoxia). • Effects: • Increases stem cell division. • Speeds up hemoglobin production. • Blood doping: Athletes take EPO or reinfuse RBCs → more oxygen for muscles. • Risk: thicker blood → clots, strokes. • Analogy: EPO = coach yelling “make more RBCs!” ⸻ Slide 12: Blood Types • RBCs have antigens on membranes (A, B, AB, O). • Rh factor = + or –. • Plasma has antibodies (agglutinins): attack foreign antigens → cause clumping (agglutination). • Universal donor = O–. • Analogy: Blood type = ID card. If ID doesn’t match, antibodies attack. ⸻ Slide 13: RBC Summary • Know: • How typing works. • How RBCs are made. • What controls them. • Why they live 120 days. • How they’re broken down. • Analogy: RBCs = delivery trucks with expiration dates. ⸻ Slide 14: WBC Basics • WBCs = leukocytes. • Have nuclei, organelles, no Hb. • Functions: fight pathogens, remove wastes, destroy abnormal cells. • Only in blood briefly → then move into tissues. • Analogy: WBCs = body’s police force. ⸻ Slide 15: Neutrophils • 50–70% of WBCs. • Nucleus 2–5 lobes. • First responders → attack bacteria. • Use phagocytosis + enzymes. • Die quickly → pus = dead neutrophils + bacteria. • Analogy: Neutrophils = foot soldiers. ⸻ Slide 16: Basophils • <1% WBCs. • Release histamine (dilates vessels, causes swelling/redness). • Release heparin (prevents clots). • Trigger inflammation → work with mast cells. • Analogy: Basophils = fire alarms. ⸻ Slide 17: Eosinophils • 2–4% WBCs. • Stain red-orange. • Bi-lobed nucleus. • Kill parasites, respond to allergies. • Release toxic chemicals (nitric oxide, enzymes). • Help control inflammation. • Analogy: Eosinophils = exterminators. ⸻ Slide 18: Monocytes • 2–8% WBCs. • Largest WBC, kidney-shaped nucleus. • Become macrophages in tissue. • Eat large pathogens, dead cells. • Call fibrocytes → scar tissue. • Analogy: Monocytes = garbage trucks. ⸻ Slide 19: Lymphocytes • 20–30% WBCs. • Big nucleus, little cytoplasm. • Most live in lymph tissue. • Types: • T cells: attack infected cells. • B cells: make antibodies. • NK cells: kill cancer/virus cells. • Analogy: Lymphocytes = special forces. ⸻ Slide 20: WBC Production • From hemocytoblasts. • Myeloid stem cells: all except lymphocytes. • Lymphoid stem cells: lymphocytes. • Colony-Stimulating Factors (CSFs): • M-CSF = monocytes. • G-CSF = granulocytes. • GM-CSF = granulocytes + monocytes. • Multi-CSF = RBCs + WBCs + platelets. • Analogy: CSFs = managers assigning jobs. ⸻ Slide 21: Platelets • Fragments of cells, no nucleus. • Lifespan = 9–12 days. • Removed by spleen. • 2/3 stored for emergencies. • Analogy: Platelets = emergency patch kits. ⸻ Slide 22: Platelet Functions 1. Release clotting chemicals. 2. Form platelet plug at damage site. 3. Contract (actin + myosin) → shrink clot, close wound. • Analogy: Platelets = patch team pulling duct tape tight. ⸻ Slide 23: Hemostasis • Definition: stopping bleeding. • 3 phases: vascular, platelet, coagulation. • Analogy: Like fixing a leaking pipe step by step. ⸻ Slide 24: Vascular Phase • Vessel wall contracts (vascular spasm). • Endothelial cells: • Expose basement membrane. • Release endothelins → stimulate contraction/healing. • Become sticky → platelets attach. • Analogy: Pinch a hose to slow the leak. ⸻ Slide 25: Platelet Phase • Platelets stick to exposed collagen. • Form platelet plug (15 sec after injury). • Release chemicals: ADP, thromboxane A₂, serotonin, Ca²⁺, PDGF. • Feedback prevents over-clotting. • Analogy: Like putting your hand over a hole until repair arrives. ⸻ Slide 26: Coagulation Phase • Chain reaction of clotting factors. • Fibrinogen → fibrin (forms net). • Common pathway: 1. Factor X → prothrombinase. 2. Prothrombin → thrombin. 3. Fibrinogen → fibrin. • Clot retraction pulls vessel edges together. • Analogy: Casting a fishing net over the leak. ⸻ Slide 27: Fibrinolysis & Clotting Needs • Fibrinolysis: clot dissolves after healing. • t-PA → activates plasminogen → plasmin → digests fibrin. • Requirements for clotting: • Calcium (Ca²⁺): needed in all clotting steps. • Vitamin K: liver makes clotting factors; comes from food + gut bacteria. • Deficiency = bleeding problems. • Analogy: Once pipe is repaired, cut away the net (clot)

shrinking 1

Lesson 4.8: Shrinking Pluto

Deregulation and shrinking of 'Big Government'

📚 8.1 How Companies Find and Develop New Product Ideas Sources of New Product Ideas: Internal Sources: R&D, employee suggestions, brainstorming sessions. External Sources: Customers: Surveys, feedback, complaints, and suggestions. Competitors: Analyzing competitors' products to identify gaps or improve upon existing ideas. Distributors/Suppliers: Insights into market trends and supply chain opportunities. Crowdsourcing: Engaging the public for innovative ideas. Developing New Ideas: Idea Screening: Filter out bad ideas early to focus on the most promising ones. Concept Development and Testing: Test concepts with target customers to gauge their response. 🔄 8.2 Steps in the New Product Development Process Idea Generation: Brainstorming ideas from internal and external sources. Idea Screening: Evaluate ideas to eliminate unfeasible ones. Concept Development and Testing: Develop product concepts and test them with target audiences. Marketing Strategy Development: Create a marketing plan for pricing, distribution, and promotion. Business Analysis: Assess the financial feasibility (cost, demand, profitability). Product Development: Build and test prototypes or minimum viable products (MVPs). Test Marketing: Introduce the product to a limited market to assess performance. Commercialization: Full-scale launch of the product. Major Considerations: Customer-Centricity: Focus on customer needs and feedback. Speed to Market: Minimize delays in the development cycle. Risk Management: Anticipate and address potential product risks. 📈 8.3 Stages of the Product Life Cycle (PLC) & Changing Marketing Strategies Introduction: High marketing costs, slow sales growth, and minimal profit. Strategy: Build awareness, offer promotions, and use selective distribution. Growth: Rapid sales increase, rising profits, and market expansion. Strategy: Improve product quality, expand distribution, and adjust pricing to maximize market share. Maturity: Sales peak, profits stabilize or decline due to competition. Strategy: Modify the product, look for new market segments, and focus on differentiation. Decline: Sales drop, profits decrease, and the market shrinks. Strategy: Harvest (reduce costs and maximize remaining profit) or divest (discontinue the product). 🌱 8.4 Additional Product Issues ✅ Socially Responsible Product Decisions: Product Safety: Ensuring products meet safety standards. Environmental Impact: Minimize environmental harm (sustainable sourcing and packaging). Ethical Marketing: Honest communication and avoiding deceptive advertising. 🌍 International Product and Services Marketing: Adaptation vs. Standardization: Adaptation: Modify the product to fit local preferences or legal requirements. Standardization: Keep the same product globally to maintain consistency. Cultural Sensitivity: Tailoring messaging and branding to align with cultural values. Regulatory Compliance: Meeting the local standards and regulations in different countries

Know the relationship between molecular weight and rate of diffusion The rate of diffusion is inversely proportional to the molecular weight Small weight-fast diffusion; heavy weight-slow diffusion Identify RBC’s in various solution and determine tonicity Tonicity - the ability of an extracellular solution to make water move into or out of a cell by osmosis If a cell is placed in a hypertonic solution, there will be a net flow of water out of the cell, and the cell will lose volume (shrink). A solution will be hypertonic to a cell if its solute concentration is higher than that inside the cell, and the solutes cannot cross the membrane. If a cell is placed in a hypotonic solution, there will be a net flow of water into the cell, the cell will gain volume (bigger). If the solute concentration outside the cell is lower than inside the cell, then solutes cannot cross the membrane, then the solution is hypotonic to the cell. If a cell is placed in an isotonic solution, there will be no set flow of water into or out of the cell, and the cell’s volume will remain stable. If the solute concentration outside the cell is the same as inside the cell, and the solutes cannot cross the membrane, the solution is isotonic to the cell. Homeostatic feedback loop for respiratory rate, heart rate and temperature Respiratory Rate: Stimulus : The level of carbon dioxide (CO2) in the blood increases (often due to exercise or hypoventilation) . Receptors: Chemoreceptors in the medulla oblongata, carotid arteries, and aortic arch detect changes in blood pH and CO2 levels Control Center: The medulla oblongata processes this information Effectors: Respiratory muscles (diaphragm and intercostal) adjust breathing rate and depth Response: Increased respiratory rate removes CO2 and increases O2 intake, restoring normal pH and gas levels. Heart Rate: Stimulus : Changes in blood pressure, O2, CO2, or pH levels Receptors: Baroreceptors (detect blood pressure changes) in the carotid sinus and aortic arch; chemoreceptors monitor blood chemistry Control Center: The medulla oblongata (cardiac center) processes signals Effectors : The autonomic nervous system (ANS) adjusts heart rate through the sympathetic nervous system (increases heart rate) or parasympathetic nervous system (decreases heart rate) Response : Heart rate increases during low O2 or low blood pressure (to circulate oxygen) and decreases when homeostasis is restored. Temperature Regulation Stimulus: Changes in body temperature (hyperthermia or hypothermia) Receptors: Thermoreceptors in the skin and hypothalamus detect temperature fluctuations. Control Center: The hypothalamus processes this information and signals effectors Effectors and Responses: If too hot: Blood vessels dilate (vasodilation) to release heat, and sweat glands produce sweat for cooling If too cold: Blood vessels constrict (vasoconstriction) to retain heat, and shivering generates warmth. Steps of a generic homeostatic feedback loop Stimulus : A change in the internal or external environment that disrupts homeostasis (eg. temperature change, pH levels, blood sugar levels) Sensor (Receptor) : Specialized cells or receptors detect the change and send information to the control center. Control Center (Integrator): Often the brain or endocrine glands, this component processes the information from the sensors and determines the appropriate response to restore balance. Effector: This component carries out the response to the stimulus as dictated by the control center. Effectors can be muscles or glands that help to counteract the change. Response: The action taken by the effectors to restore homeostasis. This could involve increasing or decreasing a physiological process (e.g. sweating to cool down or shivering to warm up) Feedback: The results of the response are monitored. If homeostasis is restored, the system maintains its state; if not, the loop may repeat, continuing to adjust until balance is achieved. How to evaluate data to determine the set point, error, and disturbance Identify the set point The set point is the optimal level or range that the system aims to maintain. To determine the set point: Gather baseline data: Collect data over a period to understand the normal range for the variable in question (e.g. body temp., BP, blood glucose levels) Analyze Trends: Look for patterns in the data to identify the average or median value that represents the stable condition of the system. Consult Literature: Reference established physiological norms or previous studies to confirm the typical set point for the variable. Assess Disturbance A disturbance is any factor or event that causes a deviation from the set point. To evaluate disturbances: Identify External and Internal Factors: Analyze the data for any external influences (e.g. environmental changes, dietary habits) or internal changes (e.g. illness, stress) that might have impacted the variable. Quantity Disturbance: Measure the magnitude and duration of the disturbance. This can be done by comparing the data points during the disturbance against the established set point. Monitor Changes: Track how the system responds to disturbances over time to assess their impact on maintaining homeostasis. WBC types and normal distribution values/ abnormal values and what those values indicate (infections/diseases) (Never Let Monkeys Eat Bananas) Neutrophils (50-70%) - First responders to infections, especially bacterial. High levels indicate bacterial infections, inflammation, or stress. Low levels can indicate bone marrow disorders or severe infections. Lymphocytes (20-40%) - Include B cells and T cells, important for immunity. High levels can suggest viral infections or leukemia, while low levels might indicate immune deficiency. Monocytes (2-8%) - Help with cleaning up dead cells and fighting infections. High levels can be linked to chronic infections or autoimmune diseases. Eosinophils (1-4%) - Involved in allergic reactions and fighting parasites. Elevated levels may indicate allergies or parasitic infections. Basophils (0.5-1%) - Release histamine during allergic reactions. High levels might be see in allergic conditions or blood disorders. Normal WBC Count Total WBC Count: 4000-11000 cells per microliter of blood (varies slightly by lab) Leukocytosis (High WBC): Can indicate infection, inflammation, stress, or leukemia Leukopenia (Low WBC): Can result from bone marrow disorders, viral infections, or autoimmune diseases Neutrophils: Banded vs Segmented Neutrophils are the most abundant type of white blood cells and play a crucial role in fighting infections. They exist in different stages of maturation: Banded Neutrophils (“Bands”) - Immature Neutrophils Appearance: Have a curved, unsegmented nucleus (band-shaped) Normal Range: 0-6% of total WBC count (~0-700/uL) Clinical Significance: Increased Bands (Bandemia) -> Indicates an acute bacterial infection or severe stress (e.g. sepsis). The bone marrow releases immature neutrophils in response to infection. Low Bands -> Not clinically significant unless the total WBC count is low, which could suggest bone marrow suppression. Segmented Neutrophils (“Segs”) - Mature Neutrophils Appearance: Have a segmented nucleus with 2-5 lobes Normal Range: 50-70% of total WBC count (~2500-7000/uL) Clinical Significance: High Segs (Neutrophilia) -> Suggests bacterial infections, stress, chronic inflammation, or leukemia Low Segs (Neutropenia) ->Can be caused by viral infections, bone marrow disorders, chemotherapy, or autoimmune diseases. Discuss the stages of cell cycle/mitosis-which stages are longest/shortest The cell cycle is a series of events that cells go through to grow and divide. It consists of two main phases: Interphase (Longest Phase) – Preparation for division Mitosis (Shortest Phase) – Actual cell division Stages of the Cell Cycle Interphase (90% of the Cell Cycle – Longest Phase) Interphase is the period of cell growth and DNA replication. It has three subphases: G1 Phase (Gap 1) The cell grows, produces proteins, and prepares for DNA replication. Longest variable phase; some cells may stay here indefinitely (e.g., neurons in G0 phase). S Phase (Synthesis) DNA replication occurs, ensuring each daughter cell gets a complete genome. Takes about 6-8 hours in human cells. G2 Phase (Gap 2) The cell prepares for mitosis by producing proteins and organelles. Shorter than G1 but still significant in length. Mitosis: Prophase, Metaphase, Anaphase, Telophase Know proportional and inversely proportional relationships Direct (Proportional) Relationship When two quantities increase or decrease together at a constant rate, they are directly proportional. Inversely Proportional When one variable increases, the other decreases proportionally. Know relationship between molecular weight and rate of diffusion The rate of diffusion of a substance is inversely proportional to the square root of its molecular weight. Lighter molecules diffuse faster Heavier molecules diffuse slower due to greater mass. Know relationship between filtration rate and pressure of fluid or weight of fluid Filtration rate is directly proportional to the pressure or weight of the fluid driving the filtration process. Higher pressure → Higher filtration rate Lower pressure → Lower filtration rate Know why men and women blood values are different The differences in blood values between men and women are due to biological, hormonal, and physiological factors

ECON 491 Lecture 14: Shrinkage/Regularization

You place a RBC (0.9%) into a 5% sugar solution. Which statement below is false? The RBC is hypotonic to the 5% solution Which is an example of a sensor in a negative homeostatic feedback loop? Chemoreceptor in carotid body For membrane fluidity experiment, the part of the experiment that actually validated that the membrane was fluid was: The labeled antibodies of the human and mouse intermixing An example of primary active transport would be a protein requiring ATP to transport sodium ions across the plasma membrane. True If a red blood cell is put in a solution and it hemolyzes, then the solution is considered to be: Hypotonic If your body temperature goes too high you can denature enzymes in your body. True What does an integrator do in a homeostatic pathway? Measures the signal coming in to a set point and send a signal out to the body Which of the following represents stages of the cell division (mitosis) in the proper sequence? Prophase, metaphase, anaphase, telophase Which is not true for proteins? They are comprised of mostly cellulose What would be a disturbance for blood glucose homeostasis (normal blood glucose set point = 77mg/dL)? A permanent decrease in insulin production from the Islets of Langerhans Dr. Bio measures your total cholesterol and he reports back to you that your level is 300 mg/ 100 ml of plasma. You do what? Eat more oatmeal and flax to increase your HDL level. How do you make an unsaturated fatty acid? Perform a dehydration synthesis reaction on a saturated fatty acid Which is false for antioxidants? They speed up reactions in your body Which molecules do not dissolve in water? Non-polar Which molecule requires a transport protein to get through the plasma membrane (either channel or carrier protein)? Two of the answers are correct Interphase is considered to be part of normal cell division (mitosis). False What is the function of ATP? All of the answers are correct What are the three kinds of lipids? Triglycerides, phospholipids, and steroids When glycerol combines with 3 fatty acids to form a triglyceride (fat), which of the following chemical reactions has occurred? Dehydration Synthesis How can you alter a protein’s shape? More than one answer is correct If a red blood cell is put into a solution and it maintains its shape, then the solution is considered to be: Isotonic Which molecule requires some type of transport protein to get through the plasma membrane? Sodium Ion Cofactors are molecules that activate enzymes. Which is not a cofactor? Mercury The nitrogenous bases found in DNA have complementary paring. Which pair is correct? C-G Which is not true for meiosis? Results in a gamete that is 2N In the diagram below the two solutions are separated by a semi permeable membrane. In which direction will net movement of water occur? From side A to side B Which is not a component of a DNA molecule: Ribose Sugar Phospholipids are similar to fatty acids except for? Phospholipids have a phosphate group Which is not true for cells? They allow diffusion of all molecules If you combine a molecule of glucose and fructose, which statement is true? You have formed sucrose Which is true for enzymes? Activity will increase until the enzyme becomes saturated What method would you use to get glucose into a cell along/down it’s concentration gradient (from high to low)? Facilitated Diffusion Which is not considered an integrator in a negative homeostatic feedback loop? Pancreas Which phase of the cell cycle is where cytokinesis takes place? Telophase What vitamin do we produce by sitting in the sun; it aids in calcium absorption from the small intestine? Vitamin D Why is it important to think about ion dissociation in the body? All the above In what order do you use macromolecules for fuel? Carbohydrates, lipids, proteins Which is false for cholesterol? It can dissolve in water/blood You place a RBC (0.9%) into a 0.5% sugar solution. Which statement below is false? The RBC is hypertonic to the 0.5% solution Which is not a membrane protein function? Protein synthesis Ingesting (eating) excess hydrophilic vitamins, such as vitamin C, results in excess vitamin C being stored in your tissues. False Diffusion is: The movement of molecules from an area of high molecular concentration to an area of low molecular concentration across a selectively-permeable membrane The hormone responsible for glucose uptake/removal from the blood is: Insulin What method would you use to get sodium ions into a cell against sodium’s concentration gradient (from low to high concentration)? Active Transport Which phase of the cell cycle is where the cell is functioning normally or doing its job? Interphase Evidence for mitochondria once being bacteria that our cells engulfed is: It has it’s own DNA Ionic molecules (ie NA+, K+) can diffuse straight through the plasma membrane. True What is the difference between cis and trans fatty acids? Cis fatty acids have hydrogens on the same side of the carbon double bond and trans fatty acids do not Cofactors are molecules that activate enzymes. Where do we get cofactors from? Vitamins found in fruits and vegetables RNA has what nitrogenous base in place of thymine? Uracil Large polar molecules (ie glucose) can diffuse straight through the plasma membrane? False Which lipoprotein is comprised of more protein and less cholesterol so it scavenges for cholesterol in the blood? High density lipoprotein A normal human being has 46 chromosomes (23 pairs/2N/diploid) in each somatic cell (body cell). True The three main compounds digested by the digestive system are? Fats, carbohydrates, and proteins Meiosis is the process in which our sex cells go from 46 chromosomes to 23 single chromosomes. True The effector in any negative feedback loop is usually: An organ/tissue If a red blood cell is put into a solution and it crenates (shrinks), then the solution is considered to be: Hypertonic Which statement is false for glycogen? It is a disaccharide Enzymes aid in digestion by? Lowering the energy required to break food apart Nonpolar molecules (ie CO2) can diffuse straight through the plasma membrane

Shrinking World