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D2.1 Cytokinesis
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07. Cytokinesis
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biology 2.1Unit 2.1: Mitosis and Meiosis Introduction By the end of this section, you should be able to: Define a chromosome. Define DNA as the genetic material. Define genes. Describe the structure of chromosomes. Describe the components of DNA. Define mitosis and describe its stages. Define meiosis and describe its stages. Relate the events of meiosis to the formation of sex cells. Compare mitosis and meiosis. Chromosomes, Genes, and DNA Almost all the cells of your body—except for mature red blood cells—contain a nucleus, which acts as the control center of the cell. The nucleus holds all the information needed to make a new cell and, ultimately, a new individual. Inside the nucleus are chromosomes, thread-like structures that store genetic information passed from parents to offspring. Chromosomes are made up of DNA (deoxyribonucleic acid), a molecule that carries the instructions needed to make all the proteins in your body. Many of these proteins are enzymes, which control the production of other chemicals and affect everything about how your body functions. Each species has a specific number of chromosomes: Humans have 46 chromosomes (23 pairs). Tomatoes have 24 chromosomes (12 pairs). Elephants have 56 chromosomes (28 pairs). Half of your chromosomes come from your mother, and the other half from your father. These chromosomes are arranged in homologous pairs, meaning they contain matching sets of genes. A karyotype is a special photograph that arranges chromosomes into their pairs. In humans, 22 pairs of chromosomes are called autosomes, which control most body functions. The 23rd pair is the sex chromosomes, which determine whether you are male or female: Females have two X chromosomes (XX). Males have one X and one Y chromosome (XY). DNA Structure DNA is a long, twisted molecule shaped like a double helix (a spiraled ladder). Each strand of DNA is made up of smaller molecules called nucleotides, which consist of: A phosphate group A sugar (deoxyribose) A nitrogen base The four nitrogen bases in DNA are: Adenine (A) → Always pairs with Thymine (T) Cytosine (C) → Always pairs with Guanine (G) Genes are small segments of DNA that carry instructions for making proteins. The sequence of these bases acts like a biological code, directing the cell to create specific proteins. In 1953, James Watson and Francis Crick, using data from Rosalind Franklin’s X-ray photographs, discovered the double-helix structure of DNA. Their discovery led to a huge increase in genetic research, including the Human Genome Project, which mapped all human genes. Mitosis (Cell Division for Growth and Repair) All body cells (somatic cells) divide using mitosis, a type of cell division that creates two identical daughter cells. Mitosis is essential for: Growth (producing new cells). Tissue repair (replacing damaged or old cells). Asexual reproduction (producing offspring with identical DNA). Stages of Mitosis Interphase The cell prepares for division by copying its DNA. Chromosomes are not visible under a microscope. Prophase Chromosomes condense and become visible. The nuclear membrane breaks down. Metaphase Chromosomes line up in the center of the cell. Spindle fibers attach to each chromosome. Anaphase The spindle fibers pull the sister chromatids apart to opposite ends of the cell. Telophase A new nuclear membrane forms around each set of chromosomes. The cell is almost ready to split. Cytokinesis The cytoplasm divides, forming two identical daughter cells. Mitosis is constantly occurring in areas like your skin and bone marrow, where new cells are needed regularly. Meiosis (Cell Division for Reproduction) Unlike mitosis, meiosis occurs only in the reproductive organs (testes in males, ovaries in females) and produces gametes (sperm and egg cells). Gametes have half the number of chromosomes (haploid, n=23) so that when fertilization occurs, the new cell has the correct chromosome number (diploid, 2n=46). Stages of Meiosis Meiosis consists of two rounds of cell division, resulting in four non-identical cells. Meiosis I: Prophase I – Chromosomes pair up and exchange genetic material (crossing over). Metaphase I – Chromosome pairs line up in the center of the cell. Anaphase I – Chromosome pairs separate and move to opposite ends of the cell. Telophase I & Cytokinesis – The cell splits into two haploid daughter cells. Meiosis II (similar to mitosis): 5. Prophase II – Chromosomes condense again. 6. Metaphase II – Chromosomes line up in the center. 7. Anaphase II – Sister chromatids separate and move to opposite sides. 8. Telophase II & Cytokinesis – Four unique haploid gametes are formed. Each gamete is genetically different due to crossing over and random chromosome distribution. Mitosis vs. Meiosis: Key Differences Importance of Mitosis and Meiosis Mitosis ensures that cells grow, repair damage, and replace old cells. Meiosis allows genetic diversity, which is essential for evolution and survival. Summary Chromosomes carry genetic information in the form of DNA. Genes are sections of DNA that code for proteins. Mitosis produces two identical daughter cells for growth and repair. Meiosis creates four non-identical sex cells for reproduction. Mitosis ensures genetic stability, while meiosis introduces genetic diversity
Updated 26d ago
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You place a RBC (0.9%) into a 5% sugar solution. Which statement below is false? The RBC is hypotonic to the 5% solution Which is an example of a sensor in a negative homeostatic feedback loop? Chemoreceptor in carotid body For membrane fluidity experiment, the part of the experiment that actually validated that the membrane was fluid was: The labeled antibodies of the human and mouse intermixing An example of primary active transport would be a protein requiring ATP to transport sodium ions across the plasma membrane. True If a red blood cell is put in a solution and it hemolyzes, then the solution is considered to be: Hypotonic If your body temperature goes too high you can denature enzymes in your body. True What does an integrator do in a homeostatic pathway? Measures the signal coming in to a set point and send a signal out to the body Which of the following represents stages of the cell division (mitosis) in the proper sequence? Prophase, metaphase, anaphase, telophase Which is not true for proteins? They are comprised of mostly cellulose What would be a disturbance for blood glucose homeostasis (normal blood glucose set point = 77mg/dL)? A permanent decrease in insulin production from the Islets of Langerhans Dr. Bio measures your total cholesterol and he reports back to you that your level is 300 mg/ 100 ml of plasma. You do what? Eat more oatmeal and flax to increase your HDL level. How do you make an unsaturated fatty acid? Perform a dehydration synthesis reaction on a saturated fatty acid Which is false for antioxidants? They speed up reactions in your body Which molecules do not dissolve in water? Non-polar Which molecule requires a transport protein to get through the plasma membrane (either channel or carrier protein)? Two of the answers are correct Interphase is considered to be part of normal cell division (mitosis). False What is the function of ATP? All of the answers are correct What are the three kinds of lipids? Triglycerides, phospholipids, and steroids When glycerol combines with 3 fatty acids to form a triglyceride (fat), which of the following chemical reactions has occurred? Dehydration Synthesis How can you alter a protein’s shape? More than one answer is correct If a red blood cell is put into a solution and it maintains its shape, then the solution is considered to be: Isotonic Which molecule requires some type of transport protein to get through the plasma membrane? Sodium Ion Cofactors are molecules that activate enzymes. Which is not a cofactor? Mercury The nitrogenous bases found in DNA have complementary paring. Which pair is correct? C-G Which is not true for meiosis? Results in a gamete that is 2N In the diagram below the two solutions are separated by a semi permeable membrane. In which direction will net movement of water occur? From side A to side B Which is not a component of a DNA molecule: Ribose Sugar Phospholipids are similar to fatty acids except for? Phospholipids have a phosphate group Which is not true for cells? They allow diffusion of all molecules If you combine a molecule of glucose and fructose, which statement is true? You have formed sucrose Which is true for enzymes? Activity will increase until the enzyme becomes saturated What method would you use to get glucose into a cell along/down it’s concentration gradient (from high to low)? Facilitated Diffusion Which is not considered an integrator in a negative homeostatic feedback loop? Pancreas Which phase of the cell cycle is where cytokinesis takes place? Telophase What vitamin do we produce by sitting in the sun; it aids in calcium absorption from the small intestine? Vitamin D Why is it important to think about ion dissociation in the body? All the above In what order do you use macromolecules for fuel? Carbohydrates, lipids, proteins Which is false for cholesterol? It can dissolve in water/blood You place a RBC (0.9%) into a 0.5% sugar solution. Which statement below is false? The RBC is hypertonic to the 0.5% solution Which is not a membrane protein function? Protein synthesis Ingesting (eating) excess hydrophilic vitamins, such as vitamin C, results in excess vitamin C being stored in your tissues. False Diffusion is: The movement of molecules from an area of high molecular concentration to an area of low molecular concentration across a selectively-permeable membrane The hormone responsible for glucose uptake/removal from the blood is: Insulin What method would you use to get sodium ions into a cell against sodium’s concentration gradient (from low to high concentration)? Active Transport Which phase of the cell cycle is where the cell is functioning normally or doing its job? Interphase Evidence for mitochondria once being bacteria that our cells engulfed is: It has it’s own DNA Ionic molecules (ie NA+, K+) can diffuse straight through the plasma membrane. True What is the difference between cis and trans fatty acids? Cis fatty acids have hydrogens on the same side of the carbon double bond and trans fatty acids do not Cofactors are molecules that activate enzymes. Where do we get cofactors from? Vitamins found in fruits and vegetables RNA has what nitrogenous base in place of thymine? Uracil Large polar molecules (ie glucose) can diffuse straight through the plasma membrane? False Which lipoprotein is comprised of more protein and less cholesterol so it scavenges for cholesterol in the blood? High density lipoprotein A normal human being has 46 chromosomes (23 pairs/2N/diploid) in each somatic cell (body cell). True The three main compounds digested by the digestive system are? Fats, carbohydrates, and proteins Meiosis is the process in which our sex cells go from 46 chromosomes to 23 single chromosomes. True The effector in any negative feedback loop is usually: An organ/tissue If a red blood cell is put into a solution and it crenates (shrinks), then the solution is considered to be: Hypertonic Which statement is false for glycogen? It is a disaccharide Enzymes aid in digestion by? Lowering the energy required to break food apart Nonpolar molecules (ie CO2) can diffuse straight through the plasma membrane
Updated 41d ago
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