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Epiglottitis
acute life-threatening infection involving the epiglottis and surrounding tissue
Sore throat, difficulty swallowing, muffled voice, fever
Drooling and Stridor
Croup (laryngeal bronchitis)
viral infection MC in 1.5-3 yo children
upper resp. symptoms, mild fever, labored breathing, retractions, hoarseness
Harsh barking cough and Stridor
Adult version of croup
laryngitis
Diaphragmatic hernia (MC on Left)
bowel sounds in chest
Cystic fibrosis
autosomal recessive disorder of exocrine glands in lungs, pancreas, sweat glands
thick mucous, clogged bronchi, bronchiectasis, malabsorption
Rhonchi, Salty sweat, Barrel chest
Tracheomalacia
lack of rigidity/floppiness of trachea
benign and self-limited with increasing age
noisy breathing (wheezing)
Stridor is ____ in respiratory tree and wheezing is ____ in respiratory tree
high; low
Bronchiolitis
bronchiolar inflammation leading to hyperinflation
MC in infants <6 months due to RSV
Tachypnea, retractions, cyanosis, wheezing, decreased breath sounds
Grunting, Hyperresonant percussion, Decreased tactile fremitus
Asthma (reactive airway disease)
small airway obstruction due to inflammation and hyperreactive airways
Edema, mucus secretion, bronchoconstriction, dyspnea epsiodes
Tachypnea, coughing, wheezing, hypoxemia
Atelectasis
incomplete expansion of lung at birth or collapsed lung
compression/obstruction resulting in resorption of air (post-operative)
Decreased tactile fremitus, deviated trachea, dull percussion
Epidemiology of Atelectasis
not a distinct disease entity, rather an associated condition or sequela
Obstructive atelectasis
bronchial occlusion and postenotic air resorption (tumor, mucus plug)
Compressive atelectasis
intrathroacic process that prevent expansion of the lung (pneumothorax, pleural effusion)
Adhesive atelectasis
surface tension of the alveoli is so hight that they collapse
Atelectasis can result from scarring due to
tuberculosis
Imaging signs (modality of choice) for atelectasis
radiographs
Differential diagnosis of atelectasis
pneumonia, pleural effusion, tumor
Bronchitis
inflammation of large airways
Acute - MC viral “chest cold”
Chronic - MC smoking
Rhonchi + wheezing during exhalation, occasional crackles
E-Cigarette or Vaping injury
respiratory failure w/low blood oxygen levels w/acute lung inflammation
dyspnea, chest/abdominal pain and NON-PRODUCTIVE COUGH
tachypnea, tachycardia, fever, hypoxemia
Pleurisy (pleuritis) - “creaking pirate ship”
inflammation of visceral and parietal pleura
secondary to PE, infection, CT disease (lupus)
Chest pain during breathing, friction rub, rapid shallow respirations, decreased breath sounds
Pleural effusion
excessive nonpurulent fluid in pleural space
Caused by: HF, infecion, renal insufficiency, CT disease, neoplasm
cough, dyspnea, pleuritic chest pain
Dull percussion, decreased tactile fremitus, decreased breath sounds
Transudative pleural fluid (protein poor)
fluid that accumulates as a result of imbalance in hydrostatic and oncotic pressure
**HF or nephrotic syndrome
Exudative pleural fluid (protein rich)
local capillary pleural membrane permeability or lymphatic blockage
**localized inflammation or malignant processes
History of a pleural effusion pt should focus on
differentiating pulmonary etiologies from cardiovascular and other causes of effusion
In a physical exam procedure of pleural effusion, the clinician should pay particular attention to
chest exam, specifically dull percussion b/c it is sensitive and specific for effusion
MC causes of pleural effusion
HF, bacterial pneumonia, pulmonary embolism
What chest radiography should be performed if suspected pleural effusion
posteroanterior and lateral
If the chest radiography is inconclusive, you should perform
CT for effusions, pleural fluid/thickening
Ultrasound b/c more accurate than auscultation and x-ray
Aspiration of pleural fluid is indiciated when
underlying cause of effusion is unknown
Signs/ Symptoms and Etiology that suggest pleural effusion
Ascites - cirrhosis
Distended neck veins/Dyspnea on exertion/Orthopnea/Peripheral edema - HF
Hemoptysis/Hepatosplenomegaly/Lymphadenopathy - malignancy
Sensitivity and Specificity (accuracy) of commone clinical findings for diagnosing pleural effusion
Asymmetric chest expansion - 74% (sens) + 91% (spec)
Reduced vocal resonance - 76% (sens) + 88% (spec)
Reduced vocal fremitus - 82% (sens) + 86% (spec)
Empyema
purulent exudative fluid collected in pleural space
Caused by: infected adjacent tissue from pneumonia
fever, tachypnea, cough, chest pain, dyspnea
Dull percussion, absent tactile fremitus, decreased breath sounds
Lung abscess (unilateral)
well circumscribed fluid containing cavity w/air fluid interface
Caused by: aspiration of food or infection
Dull percussion, pleural friction rub, decreased breath sounds, PRODUCTIVE/purulent cough, foul-smelling sputum
Pneumonia (unilateral)
inflammatory response of bronchioles and alveoli (parenchyma)
fever, tachypnea, tachycardia
PRODUCTIVE cough, pleuritic chest pain, dyspnea, chills, rigors
Crackles, rhonchi, dull percussion, increased tactile fremitus, vocal resonance louder
Bronchovesciular sounds - alveoli are filled w/fluid
Bloody sputum is typically associated with what type of pneumonia and influenza
bacterial
Influenza
viral infection of lung w/interstitial inflammation and necrosis
cough, fever, malaise, headache, sore throat
Crackles, rhonchi, wheezes, tachypnea
COVID-19
viral infection from SARS-CoV2
transmitted via respiratory secretions
Crackles, wheezes, rhonchi, tachypnea
What disease is typically asymptomatic in the latent period
tuberculosis
Tuberculosis
chronic infectious disease begins in lung by can spread
transmitted via coughing and sneezing, traveling to endemic regions
fever, blood streaked cough, weight loss, night sweats
Pneumothorax (gas in pleural cavity)
Caused by: trauma, spontaneous rupture of bleb
Mediastinal shift, tracheal deviation, hyperresonant percussion, decreased tactile fremitus, decreased breath sounds
Tension pneumothorax
increasing pressure in pleural space
Hemothorax (blood in plerual cavity)
Caused by: trauma or medical procedures
Tachycardia and hypotension
Dull percussion, decreased tactile fremitus, decreased breath sounds
Hemopneumothorax (air and blood in pleural cavity) acts like
pleural effusion
Lung cancer (bronchogenic carcinoma)
malignant tumor that evolves from bronchial epithelial structures
can develop pneumonia or pleural effusion
dull percussion, increased tactile fremitus, decreased breath sounds
Pulmonary embolism
RF: age, DVT, surgery, heart disease, cancer, bed rest
pleuritic chest pain (hurts when actively breathing), fever, hypoxia, tachycardia
Pulmonary embolism is difficult to diagnose, what two tests are used
Wells PE prediction rule
D-dimer test
Wells PE prediction rule
score <2 = low risk PE (7%)
score 2-6 = intermediate risk PE
score >6 = high risk PE (>45%)
If the Wells PE prediction rule shows an intermediate risk, what are your next steps
order a D-dimer test
D-dimer test
protein fragment from blood clot formation and breakdown
If the Wells PE prediction rule shows a high risk, what are your next steps
straight to the ER
Cor pulmonale
acute/chronic condition involving right sided HF
Associated w: COPD, asthma, cystic fibrosis, bronchiectasis
Pulmonary edema (fluid in airways) (bilateral)
Cardiogenic (MC) - HF leading to backup of circulation in lungs
Non-cardiogenic - altitude sickness, lung transplant, foreign body
dyspnea, tachypnea, pink frothy sputum, hypoxemia
Crackles (lower lung fields), dull percussion, increased tactile fremitus
COPD (emphysema, bronchiectasis, chronic bronchitis)
cough, excessive sputum production, dyspnea, cyanosis, clubbing
smokers at greatest risk
Emphysema
lungs lose elasticity and alveoli enlarge
MC due to smoking
Dyspnea, barrel chested, decreased breath sounds, crackles, wheezes, rhonchi, hyperresonant percussion, decreased tactile fremitus
Bronchiectasis
chronic dilation of bronchi/bronchioles
Caused by: repeated pulmonary infections and bronchial obstruction
cough w/large amounts of sputum, hemoptysis, tachypnea, clubbing, crackles, rhonchi
Bronchiectasis is frequently with
cystic fibrosis
Chronic bronchitis
large airway inflammation
Caused by: chronic irritant exposure
MC >40 yo