Bio Chem Exam #4

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162 Terms

1
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enzyme whose endergonic nature depends on keto-enol tautomerism

\


alanine



\


citrate



\


cortisol



\


FoxO1



\


GAPDH



\


glucokinase



\


hexokinase



\


malate



\


PEPCK



\


3-phosphoglycerate



\


phosphoglycerate kinase



\


pyruvate carboxylase



\


pyruvate kinase



\


succinylCoA synthetase in the CAC



 

pyruvate kinase
2
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exported compound during high levels of beta oxidation which allosterically activates fructose-1,6-bisphosphatase

\


alanine



\


citrate



\


cortisol



\


FoxO1



\


GAPDH



\


glucokinase



\


hexokinase



\


malate



\


PEPCK



\


3-phosphoglycerate



\


phosphoglycerate kinase



\


pyruvate carboxylase



\


pyruvate kinase



\


succinylCoA synthetase in the CAC



 



citrate
3
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product of the adrenal cortex that activates PEPCK and fructose-1,6-bisphosphatase expression



alanine



\


citrate



\


cortisol



\


FoxO1



\


GAPDH



\


glucokinase



\


hexokinase



\


malate



\


PEPCK



\


3-phosphoglycerate



\


phosphoglycerate kinase



\


pyruvate carboxylase



\


pyruvate kinase



\


succinylCoA synthetase in the CAC



 

cortisol
4
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mitochondrial enzyme using a biotin cofactor

\


alanine



\


citrate



\


cortisol



\


FoxO1



\


GAPDH



\


glucokinase



\


hexokinase



\


malate



\


PEPCK



\


3-phosphoglycerate



\


phosphoglycerate kinase



\


pyruvate carboxylase



\


pyruvate kinase



\


succinylCoA synthetase in the CAC



 



pyruvate carboxylase
5
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redox enzyme that forms a thioester bond to substrate

\


alanine



\


citrate



\


cortisol



\


FoxO1



\


GAPDH



\


glucokinase



\


hexokinase



\


malate



\


PEPCK



\


3-phosphoglycerate



\


phosphoglycerate kinase



\


pyruvate carboxylase



\


pyruvate kinase



\


succinylCoA synthetase in the CAC



 



GAPDH
6
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source of GTP for PEPCK

\


alanine



\


citrate



\


cortisol



\


FoxO1



\


GAPDH



\


glucokinase



\


hexokinase



\


malate



\


PEPCK



\


3-phosphoglycerate



\


phosphoglycerate kinase



\


pyruvate carboxylase



\


pyruvate kinase



\


succinylCoA synthetase in the CAC



 



succinyl coA synthetase in the CAC
7
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gluconeogenic enzyme requiring especially high levels of ATP

\


alanine



\


citrate



\


cortisol



\


FoxO1



\


GAPDH



\


glucokinase



\


hexokinase



\


malate



\


PEPCK



\


3-phosphoglycerate



\


phosphoglycerate kinase



\


pyruvate carboxylase



\


pyruvate kinase



\


succinylCoA synthetase in the CAC



 



phosphoglycerate kinase
8
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enzyme with a high Km for glucose which invests an ATP for retention in the Islet beta cell

\


alanine



\


citrate



\


cortisol



\


FoxO1



\


GAPDH



\


glucokinase



\


hexokinase



\


malate



\


PEPCK



\


3-phosphoglycerate



\


phosphoglycerate kinase



\


pyruvate carboxylase



\


pyruvate kinase



\


succinylCoA synthetase in the CAC



 

glucokinase
9
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allosterically inhibits pyruvate kinase

\


alanine



\


citrate



\


cortisol



\


FoxO1



\


GAPDH



\


glucokinase



\


hexokinase



\


malate



\


PEPCK



\


3-phosphoglycerate



\


phosphoglycerate kinase



\


pyruvate carboxylase



\


pyruvate kinase



\


succinylCoA synthetase in the CAC



 



alanine
10
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compound whose low energy drives the exergonic nature of the production of "profit" ATPs during glycolysis

\


alanine



\


citrate



\


cortisol



\


FoxO1



\


GAPDH



\


glucokinase



\


hexokinase



\


malate



\


PEPCK



\


3-phosphoglycerate



\


phosphoglycerate kinase



\


pyruvate carboxylase



\


pyruvate kinase



\


succinylCoA synthetase in the CAC



 

3-phosphoglycerate
11
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enzyme with a low Km for glucose which invests an ATP for retention within the muscle cell



alanine



\


citrate



\


cortisol



\


FoxO1



\


GAPDH



\


glucokinase



\


hexokinase



\


malate



\


PEPCK



\


3-phosphoglycerate



\


phosphoglycerate kinase



\


pyruvate carboxylase



\


pyruvate kinase



\


succinylCoA synthetase in the CAC



 



hexokinase
12
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anchoring transcription factor for the GRs bound to weak GREs whose function is negated by Akt/PKB action

\


alanine



\


citrate



\


cortisol



\


FoxO1



\


GAPDH



\


glucokinase



\


hexokinase



\


malate



\


PEPCK



\


3-phosphoglycerate



\


phosphoglycerate kinase



\


pyruvate carboxylase



\


pyruvate kinase



\


succinylCoA synthetase in the CAC



 

Fox01
13
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cytoplasmic gluconeogenic enzyme using a biotin cofactor

\


alanine



\


citrate



\


cortisol



\


FoxO1



\


GAPDH



\


glucokinase



\


hexokinase



\


malate



\


PEPCK



\


3-phosphoglycerate



\


phosphoglycerate kinase



\


pyruvate carboxylase



\


pyruvate kinase



\


succinylCoA synthetase in the CAC



 



PEPCK
14
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reduced form of OAA that is channeled to the cytoplasm to feed gluconeogenesis

\


alanine



\


citrate



\


cortisol



\


FoxO1



\


GAPDH



\


glucokinase



\


hexokinase



\


malate



\


PEPCK



\


3-phosphoglycerate



\


phosphoglycerate kinase



\


pyruvate carboxylase



\


pyruvate kinase



\


succinylCoA synthetase in the CAC



 

malate
15
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Match from CAPS to: PEPCK


Match from CAPS to: PEPCK

G
16
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Match from CAPS to: PYRUVATE KINASE


Match from CAPS to: PYRUVATE KINASE

F
17
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Match from CAPS to: HEXOKINASE


Match from CAPS to: HEXOKINASE

A
18
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Match from lower case letters to: pyruvate


Match from lower case letters to: pyruvate

j
19
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Match from CAPS to: LDH


Match from CAPS to: LDH

J
20
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Match from lower case letters to: glucose


Match from lower case letters to: glucose

a
21
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Match from CAPS to: FRUCTOSE-1,6-BISPHOSPHATASE


Match from CAPS to: FRUCTOSE-1,6-BISPHOSPHATASE

K
22
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Match from lower case letters to: NADH


Match from lower case letters to: NADH

r
23
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Match from lower case letters to: ATP


Match from lower case letters to: ATP

m
24
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Match from lower case letters to: fructose-1,6-bisphosphate


Match from lower case letters to: fructose-1,6-bisphosphate

d
25
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Match from lower case letters to: acetylCoA


Match from lower case letters to: acetylCoA

u
26
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Match from lower case letters to: ADP


Match from lower case letters to: ADP

n
27
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Match from lower case letters to: glyceraldehyde-3-phosphate


Match from lower case letters to: glyceraldehyde-3-phosphate

e
28
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Match from lower case letters to: GDP


Match from lower case letters to: GDP

s
29
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Match from lower case letters to: fructose-6-phosphate


Match from lower case letters to: fructose-6-phosphate

c
30
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Match from lower case letters to: NAD+


Match from lower case letters to: NAD+

o
31
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Match from lower case letters to: lactate


Match from lower case letters to: lactate

g

Match from lower case letters to: oxaloacetate
32
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Match from lower case letters to: oxaloacetate


Match from lower case letters to: oxaloacetate

k
33
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Match from lower case letters to: glucose-6-phosphate


Match from lower case letters to: glucose-6-phosphate

b
34
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Match from lower case letters to: phosphoenolpyruvate


Match from lower case letters to: phosphoenolpyruvate

i
35
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Match from CAPS to: PYRUVATE CARBOXYLASE


Match from CAPS to: PYRUVATE CARBOXYLASE

H
36
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Match from lower case letters to: 1,3-bisphosphoglycerate


Match from lower case letters to: 1,3-bisphosphoglycerate

f
37
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\
  

Match from lower case letters to: AMP


\


Match from lower case letters to: AMP
v
38
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Match from CAPS to: GAPDH


Match from CAPS to: GAPDH
D
39
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Match from CAPS to: PFK-1


Match from CAPS to: PFK-1
C
40
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Match from CAPS to: GLUCOSE-6-PHOSPHATASE


Match from CAPS to: GLUCOSE-6-PHOSPHATASE
B
41
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Match from lower case letters to: 3-phsophoglycerate


Match from lower case letters to: 3-phsophoglycerate
h
42
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Match from lower case letters to: GTP


Match from lower case letters to: GTP
t
43
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Match from CAPS to: PHOSPHOGLYCERATE KINASE


 



Match from CAPS to: PHOSPHOGLYCERATE KINASE
E
44
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decarboxylates a three-carbon alpha keto acid, reducing NAD+ with the bond electrons, and producing a thioester bond of the remaining two-carbon product to CoA

Citrate synthase

PDH

Cytochrome b-c1 complex (III)

Aspartic acid

Gamma subunit

Alpha/beta subunit T state

Alpha-ketoglutarate dehydrogenase

NADH dehydrogenase (complex I)

Succinate dehydrogenase

Cytochrome c oxidase

Isocitrate dehydrogenase

Alpha/beta subunit L state

Arginine

Malate dehydrogenase

Lysine

Alpha/beta subunit O state

Aspartate

Glutamate 

Succinyl-CoA synthetase
PDH
45
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hydrolyzes a thioester-bonded six-carbon intermediate in a highly exergonic standard state reaction

Citrate synthase 

PDH 

Cytochrome b-c1 complex (III) 

Aspartic acid 

Gamma subunit 

Alpha/beta subunit T state 

Alpha-ketoglutarate dehydrogenase 

NADH dehydrogenase (complex I) 

Succinate dehydrogenase 

Cytochrome c oxidase 

Isocitrate dehydrogenase 

Alpha/beta subunit L state 

Arginine 

Malate dehydrogenase 

Lysine 

Alpha/beta subunit O state 

Aspartate 

Glutamate 

Succinyl-CoA synthetase 
Citrate synthase
46
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performs simple hydride transfer reduction of NAD+ combined with decarboxylation in an exergonic standard state reaction

Citrate synthase 

PDH 

Cytochrome b-c1 complex (III) 

Aspartic acid 

Gamma subunit 

Alpha/beta subunit T state 

Alpha-ketoglutarate dehydrogenase 

NADH dehydrogenase (complex I) 

Succinate dehydrogenase 

Cytochrome c oxidase 

Isocitrate dehydrogenase 

Alpha/beta subunit L state 

Arginine 

Malate dehydrogenase 

Lysine 

Alpha/beta subunit O state 

Aspartate 

Glutamate 

Succinyl-CoA synthetase 
isocitrate dehydrogenase
47
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decarboxylates a five-carbon alpha keto acid, reducing NAD+ with the bond electrons, and producing a thioester bond of the remaining four-carbon product to CoA

Citrate synthase 

PDH 

Cytochrome b-c1 complex (III) 

Aspartic acid 

Gamma subunit 

Alpha/beta subunit T state 

Alpha-ketoglutarate dehydrogenase 

NADH dehydrogenase (complex I) 

Succinate dehydrogenase 

Cytochrome c oxidase 

Isocitrate dehydrogenase 

Alpha/beta subunit L state 

Arginine 

Malate dehydrogenase 

Lysine 

Alpha/beta subunit O state 

Aspartate 

Glutamate 

Succinyl-CoA synthetase 
alpha-ketoglutarate dehydrogenase  
48
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phosphorylyzes a thioester-bonded four-carbon compound to produce an acyl-phosphate that participates in substrate-level phosphorylation

Citrate synthase 

PDH 

Cytochrome b-c1 complex (III) 

Aspartic acid 

Gamma subunit 

Alpha/beta subunit T state 

Alpha-ketoglutarate dehydrogenase 

NADH dehydrogenase (complex I) 

Succinate dehydrogenase 

Cytochrome c oxidase 

Isocitrate dehydrogenase 

Alpha/beta subunit L state 

Arginine 

Malate dehydrogenase 

Lysine 

Alpha/beta subunit O state 

Aspartate 

Glutamate 

Succinyl-CoA synthetase 
succinyl-CoA synthetase  
49
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inner membrane complex that conducts a redox reaction as part of the CAC to donate electrons directly to the ETS

Citrate synthase 

PDH 

Cytochrome b-c1 complex (III) 

Aspartic acid 

Gamma subunit 

Alpha/beta subunit T state 

Alpha-ketoglutarate dehydrogenase 

NADH dehydrogenase (complex I) 

Succinate dehydrogenase 

Cytochrome c oxidase 

Isocitrate dehydrogenase 

Alpha/beta subunit L state 

Arginine 

Malate dehydrogenase 

Lysine 

Alpha/beta subunit O state 

Aspartate 

Glutamate 

Succinyl-CoA synthetase 
succinate dehydrogenase
50
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performs simple hydride transfer reduction of NAD+ in a highly endergonic standard state reaction

Citrate synthase 

PDH 

Cytochrome b-c1 complex (III) 

Aspartic acid 

Gamma subunit 

Alpha/beta subunit T state 

Alpha-ketoglutarate dehydrogenase 

NADH dehydrogenase (complex I) 

Succinate dehydrogenase 

Cytochrome c oxidase 

Isocitrate dehydrogenase 

Alpha/beta subunit L state 

Arginine 

Malate dehydrogenase 

Lysine 

Alpha/beta subunit O state 

Aspartate 

Glutamate 

Succinyl-CoA synthetase 
 malate dehydrogenase   
51
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uses high energy electrons to both pump matrix protons and loading matrix protons on a ubiquinol to carry them to the intermembrane space

Citrate synthase 

PDH 

Cytochrome b-c1 complex (III) 

Aspartic acid 

Gamma subunit 

Alpha/beta subunit T state 

Alpha-ketoglutarate dehydrogenase 

NADH dehydrogenase (complex I) 

Succinate dehydrogenase 

Cytochrome c oxidase 

Isocitrate dehydrogenase 

Alpha/beta subunit L state 

Arginine 

Malate dehydrogenase 

Lysine 

Alpha/beta subunit O state 

Aspartate 

Glutamate 

Succinyl-CoA synthetase 
NADH dehydrogenase (complex 1) 
52
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uses a covalently-bound FAD to donate CAC electrons and matrix protons reduce of ubiquinone

Citrate synthase 

PDH 

Cytochrome b-c1 complex (III) 

Aspartic acid 

Gamma subunit 

Alpha/beta subunit T state 

Alpha-ketoglutarate dehydrogenase 

NADH dehydrogenase (complex I) 

Succinate dehydrogenase 

Cytochrome c oxidase 

Isocitrate dehydrogenase 

Alpha/beta subunit L state 

Arginine 

Malate dehydrogenase 

Lysine 

Alpha/beta subunit O state 

Aspartate 

Glutamate 

Succinyl-CoA synthetase 
succinate dehydrogenase  
53
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delivers ubiquinone protons to the intermembrane space and electrons to multiple cytochrome-c-s

Citrate synthase 

PDH 

Cytochrome b-c1 complex (III) 

Aspartic acid 

Gamma subunit 

Alpha/beta subunit T state 

Alpha-ketoglutarate dehydrogenase 

NADH dehydrogenase (complex I) 

Succinate dehydrogenase 

Cytochrome c oxidase 

Isocitrate dehydrogenase 

Alpha/beta subunit L state 

Arginine 

Malate dehydrogenase 

Lysine 

Alpha/beta subunit O state 

Aspartate 

Glutamate 

Succinyl-CoA synthetase 
cytochrome b-c1 complex (III) 
54
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uses cytochrome-c provided electrons to reduce molecular oxygen to produce low energy water

Citrate synthase 

PDH 

Cytochrome b-c1 complex (III) 

Aspartic acid 

Gamma subunit 

Alpha/beta subunit T state 

Alpha-ketoglutarate dehydrogenase 

NADH dehydrogenase (complex I) 

Succinate dehydrogenase 

Cytochrome c oxidase 

Isocitrate dehydrogenase 

Alpha/beta subunit L state 

Arginine 

Malate dehydrogenase 

Lysine 

Alpha/beta subunit O state 

Aspartate 

Glutamate 

Succinyl-CoA synthetase 
cytochrome c oxidase 
55
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in order, each of the ten c subunits of the merry-go-round of ATP synthase first donate a proton from its _____ to the matrix when it comes into contact with the a subunit's half channel to the matrix

Citrate synthase 

PDH 

Cytochrome b-c1 complex (III) 

Aspartic acid 

Gamma subunit 

Alpha/beta subunit T state 

Alpha-ketoglutarate dehydrogenase 

NADH dehydrogenase (complex I) 

Succinate dehydrogenase 

Cytochrome c oxidase 

Isocitrate dehydrogenase 

Alpha/beta subunit L state 

Arginine 

Malate dehydrogenase 

Lysine 

Alpha/beta subunit O state 

Aspartate 

Glutamate 

Succinyl-CoA synthetase 
aspartic acid  
56
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the c subunit become negatively charged at first contact with a subunit because of its deprotonated ______

Citrate synthase 

PDH 

Cytochrome b-c1 complex (III) 

Aspartic acid 

Gamma subunit 

Alpha/beta subunit T state 

Alpha-ketoglutarate dehydrogenase 

NADH dehydrogenase (complex I) 

Succinate dehydrogenase 

Cytochrome c oxidase 

Isocitrate dehydrogenase 

Alpha/beta subunit L state 

Arginine 

Malate dehydrogenase 

Lysine 

Alpha/beta subunit O state 

Aspartate 

Glutamate 

Succinyl-CoA synthetase 
aspartate
57
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movement of the merry-go-round is powered by the attraction of the negatively charged c subunit to _____ at the end of the a subunit's half channel from the intermembrane space

Citrate synthase 

PDH 

Cytochrome b-c1 complex (III) 

Aspartic acid 

Gamma subunit 

Alpha/beta subunit T state 

Alpha-ketoglutarate dehydrogenase 

NADH dehydrogenase (complex I) 

Succinate dehydrogenase 

Cytochrome c oxidase 

Isocitrate dehydrogenase 

Alpha/beta subunit L state 

Arginine 

Malate dehydrogenase 

Lysine 

Alpha/beta subunit O state 

Aspartate 

Glutamate 

Succinyl-CoA synthetase 
arginine  
58
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The a subunit's ____ protonates the c subunit and is itself re-protonated from protons delivered to it by the half channel from the intermembrane space

Citrate synthase 

PDH 

Cytochrome b-c1 complex (III) 

Aspartic acid 

Gamma subunit 

Alpha/beta subunit T state 

Alpha-ketoglutarate dehydrogenase 

NADH dehydrogenase (complex I) 

Succinate dehydrogenase 

Cytochrome c oxidase 

Isocitrate dehydrogenase 

Alpha/beta subunit L state 

Arginine 

Malate dehydrogenase 

Lysine 

Alpha/beta subunit O state 

Aspartate 

Glutamate 

Succinyl-CoA synthetase 
 arginine 
59
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the turning of the merry-go-round turns a _____ cam-shaft which produces the changes among the three states of the three alpha/beta dimeric enzymes that synthesize ATP

Citrate synthase 

PDH 

Cytochrome b-c1 complex (III) 

Aspartic acid 

Gamma subunit 

Alpha/beta subunit T state 

Alpha-ketoglutarate dehydrogenase 

NADH dehydrogenase (complex I) 

Succinate dehydrogenase 

Cytochrome c oxidase 

Isocitrate dehydrogenase 

Alpha/beta subunit L state 

Arginine 

Malate dehydrogenase 

Lysine 

Alpha/beta subunit O state 

Aspartate 

Glutamate 

Succinyl-CoA synthetase 
gamma subunit 
60
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ADP + Pi bind to the ____ during ATP synthase action

Citrate synthase 

PDH 

Cytochrome b-c1 complex (III) 

Aspartic acid 

Gamma subunit 

Alpha/beta subunit T state 

Alpha-ketoglutarate dehydrogenase 

NADH dehydrogenase (complex I) 

Succinate dehydrogenase 

Cytochrome c oxidase 

Isocitrate dehydrogenase 

Alpha/beta subunit L state 

Arginine 

Malate dehydrogenase 

Lysine 

Alpha/beta subunit O state 

Aspartate 

Glutamate 

Succinyl-CoA synthetase 
 alpha/beta subunit L state  
61
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a water molecule is withdrawn and trapped as ATP is synthesized in the _____ of ATP synthase

Citrate synthase 

PDH 

Cytochrome b-c1 complex (III) 

Aspartic acid 

Gamma subunit 

Alpha/beta subunit T state 

Alpha-ketoglutarate dehydrogenase 

NADH dehydrogenase (complex I) 

Succinate dehydrogenase 

Cytochrome c oxidase 

Isocitrate dehydrogenase 

Alpha/beta subunit L state 

Arginine 

Malate dehydrogenase 

Lysine 

Alpha/beta subunit O state 

Aspartate 

Glutamate 

Succinyl-CoA synthetase 
alpha/beta subunit T state 
62
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a water molecule is withdrawn and trapped as ATP is synthesized in the _____ of ATP synthase

Citrate synthase 

PDH 

Cytochrome b-c1 complex (III) 

Aspartic acid 

Gamma subunit 

Alpha/beta subunit T state 

Alpha-ketoglutarate dehydrogenase 

NADH dehydrogenase (complex I) 

Succinate dehydrogenase 

Cytochrome c oxidase 

Isocitrate dehydrogenase 

Alpha/beta subunit L state 

Arginine 

Malate dehydrogenase 

Lysine 

Alpha/beta subunit O state 

Aspartate 

Glutamate 

Succinyl-CoA synthetase 
alpha/beta subunit T state 
63
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a parallel beta sheet is disrupted by the spinning camshaft to release ATP and water in the ____ of ATP synthase

Citrate synthase 

PDH 

Cytochrome b-c1 complex (III) 

Aspartic acid 

Gamma subunit 

Alpha/beta subunit T state 

Alpha-ketoglutarate dehydrogenase 

NADH dehydrogenase (complex I) 

Succinate dehydrogenase 

Cytochrome c oxidase 

Isocitrate dehydrogenase 

Alpha/beta subunit L state 

Arginine 

Malate dehydrogenase 

Lysine 

Alpha/beta subunit O state 

Aspartate 

Glutamate 

Succinyl-CoA synthetase 
 alpha/beta subunit O state  
64
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in the water trap of ATP synthase what interacts with the polar H's of water?

Citrate synthase 

PDH 

Cytochrome b-c1 complex (III) 

Aspartic acid 

Gamma subunit 

Alpha/beta subunit T state 

Alpha-ketoglutarate dehydrogenase 

NADH dehydrogenase (complex I) 

Succinate dehydrogenase 

Cytochrome c oxidase 

Isocitrate dehydrogenase 

Alpha/beta subunit L state 

Arginine 

Malate dehydrogenase 

Lysine 

Alpha/beta subunit O state 

Aspartate 

Glutamate 

Succinyl-CoA synthetase 
glutamate  
65
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in the water trap of ATP synthase what interacts with the polar O of water?

Citrate synthase 

PDH 

Cytochrome b-c1 complex (III) 

Aspartic acid 

Gamma subunit 

Alpha/beta subunit T state 

Alpha-ketoglutarate dehydrogenase 

NADH dehydrogenase (complex I) 

Succinate dehydrogenase 

Cytochrome c oxidase 

Isocitrate dehydrogenase 

Alpha/beta subunit L state 

Arginine 

Malate dehydrogenase 

Lysine 

Alpha/beta subunit O state 

Aspartate 

Glutamate 

Succinyl-CoA synthetase 
lysine 
66
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When a cytoplasmic NADH is worth 2.5 ATPs in mitochondrial oxidative phosphorylation, matrix OAA is exported to the cytoplasm as _____. 

aspartate 

AMP

UCP1  

DHAP 

 ETS 

glycerol 3P 

butyrate

malate 

hydrogen peroxide  

 Semiequinoes

superoxide 

peroxiredoxin

thioredoxin 

fructose-2,6-bisphosphate 

Fructose 6-phosphate 

BCl2 

JNK 


aspartate 

67
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When a cytoplasmic NADH is worth 2.5 ATPs in mitochondrial oxidative phosphorylation, cytoplasmic OAA is imported into the matrix as reduced _____. 



aspartate 



AMP



UCP1  



DHAP 



 ETS 



glycerol 3P 



butyrate



malate 



hydrogen peroxide  



 Semiequinoes



superoxide 



peroxiredoxin



thioredoxin 



fructose-2,6-bisphosphate 



Fructose 6-phosphate 



BCl2 



JNK 

malate 

68
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When a cytoplasmic NADH is worth 1.5 ATPs, it is first used to reduce _____. 

aspartate 

AMP

UCP1  

DHAP 

 ETS 

glycerol 3P 

butyrate

malate 

hydrogen peroxide  

 Semiequinoes

superoxide 

peroxiredoxin

thioredoxin 

fructose-2,6-bisphosphate 

Fructose 6-phosphate 

BCl2 

JNK 
DHAP
69
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When a cytoplasmic NADH is worth 1.5 ATPs, electrons are donated to the ETS at the inner membrane by _____. 

aspartate 

AMP

UCP1  

DHAP 

 ETS 

glycerol 3P 

butyrate

malate 

hydrogen peroxide  

 Semiequinoes

superoxide 

peroxiredoxin

thioredoxin 

fructose-2,6-bisphosphate 

Fructose 6-phosphate 

BCl2 

JNK 
glycerol 3P 
70
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In response to active thyroid hormone (T3), the protein _____ is produced to activate non-productive movement protons back through the mitochondrial inner membrane to the matrix. 

aspartate 

AMP

UCP1  

DHAP 

 ETS 

glycerol 3P 

butyrate

malate 

hydrogen peroxide  

 Semiequinoes

superoxide 

peroxiredoxin

thioredoxin 

fructose-2,6-bisphosphate 

Fructose 6-phosphate 

BCl2 

JNK 


UCP1 

71
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During thyroid hormone (T3) leakage of protons, the compound _____ is channeled from the matrix to the intermembrane space where it becomes protonated, and returns through the membrane to the matrix to deprotonate. 

aspartate 

AMP

UCP1  

DHAP 

 ETS 

glycerol 3P 

butyrate

malate 

hydrogen peroxide  

 Semiequinoes

superoxide 

peroxiredoxin

thioredoxin 

fructose-2,6-bisphosphate 

Fructose 6-phosphate 

BCl2 

JNK 


butyrate 

72
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In response to non-productive movement of protons back through the inner membrane to the matrix, reduced chemiosmosis leads to the production of heat due to increased activation of the _____. 

aspartate 

AMP

UCP1  

DHAP 

 ETS 

glycerol 3P 

butyrate

malate 

hydrogen peroxide  

 Semiequinoes

superoxide 

peroxiredoxin

thioredoxin 

fructose-2,6-bisphosphate 

Fructose 6-phosphate 

BCl2 

JNK 
ETS
73
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In response to non-productive movement of protons back through the inner membrane to the matrix, reduced chemiosmosis leads to an increase in ____ which signals glucose uptake and activation of PFK1. 

aspartate 

AMP

UCP1  

DHAP 

 ETS 

glycerol 3P 

butyrate

malate 

hydrogen peroxide  

 Semiequinoes

superoxide 

peroxiredoxin

thioredoxin 

fructose-2,6-bisphosphate 

Fructose 6-phosphate 

BCl2 

JNK 
AMP 
74
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The rate of chemiosmosis is regulated mainly by the concentration of _____ which represents cytoplasmic energy demand.

aspartate 

AMP

UCP1  

DHAP 

 ETS 

glycerol 3P 

butyrate

malate 

hydrogen peroxide  

 Semiequinoes

superoxide 

peroxiredoxin

thioredoxin 

fructose-2,6-bisphosphate 

Fructose 6-phosphate 

BCl2 

JNK 
ADP
75
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In response to hyperglycemia, sensitive cells decrease the rate of chemiosmosis by decreased levels of ____. 

aspartate 

AMP

UCP1  

DHAP 

 ETS 

glycerol 3P 

butyrate

malate 

hydrogen peroxide  

 Semiequinoes

superoxide 

peroxiredoxin

thioredoxin 

fructose-2,6-bisphosphate 

Fructose 6-phosphate 

BCl2 

JNK 
ADP
76
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During hyperglycemia, there is an abnormally large supply of electrons in the ETS, which with low matrix protons leads to the overproduction of _____. 

aspartate 

AMP

UCP1  

DHAP 

 ETS 

glycerol 3P 

butyrate

malate 

hydrogen peroxide  

 Semiequinoes

superoxide 

peroxiredoxin

thioredoxin 

fructose-2,6-bisphosphate 

Fructose 6-phosphate 

BCl2 

JNK 


Semiequinoes

77
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Semiquinones most directly activate the production of ____. 

aspartate 

AMP

UCP1  

DHAP 

 ETS 

glycerol 3P 

butyrate

malate 

hydrogen peroxide  

 Semiequinoes

superoxide 

peroxiredoxin

thioredoxin 

fructose-2,6-bisphosphate 

Fructose 6-phosphate 

BCl2 

JNK 
superoxide
78
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SOD converts superoxide into ____.

aspartate 

AMP

UCP1  

DHAP 

 ETS 

glycerol 3P 

butyrate

malate 

hydrogen peroxide  

 Semiequinoes

superoxide 

peroxiredoxin

thioredoxin 

fructose-2,6-bisphosphate 

Fructose 6-phosphate 

BCl2 

JNK 
hydrogen peroxide  
79
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The major method of removing hydrogen peroxide within the cell is by reducing it with hydrides donated by a pair of cysteines in the protein ____. 

aspartate 

AMP

UCP1  

DHAP 

 ETS 

glycerol 3P 

butyrate

malate 

hydrogen peroxide  

 Semiequinoes

superoxide 

peroxiredoxin

thioredoxin 

fructose-2,6-bisphosphate 

Fructose 6-phosphate 

BCl2 

JNK 
peroxiredoxin 
80
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Oxidized peroxiredoxin is reduced by ____. 



aspartate 



AMP



UCP1  



DHAP 



 ETS 



glycerol 3P 



butyrate



malate 



hydrogen peroxide  



 Semiequinoes



superoxide 



peroxiredoxin



thioredoxin 



fructose-2,6-bisphosphate 



Fructose 6-phosphate 



BCl2 



JNK 

thioredoxin  
81
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Apoptosis signaling kinase-1 is prevented from forming its activating homodimeric, disulfide-bridged state by the formation of a competing disulfide-bridged heterodimer with ____. 

aspartate 

AMP

UCP1  

DHAP 

 ETS 

glycerol 3P 

butyrate

malate 

hydrogen peroxide  

 Semiequinoes

superoxide 

peroxiredoxin

thioredoxin 

fructose-2,6-bisphosphate 

Fructose 6-phosphate 

BCl2 

JNK 
thioredoxin 
82
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When supplies of reduced thioredoxin levels are lowered by ROS demand on the cell, Ask1 will phosphorylate ____ which unmasks the binding site found on the protein Bim.

aspartate 

AMP

UCP1  

DHAP 

 ETS 

glycerol 3P 

butyrate

malate 

hydrogen peroxide  

 Semiequinoes

superoxide 

peroxiredoxin

thioredoxin 

fructose-2,6-bisphosphate 

Fructose 6-phosphate 

BCl2 

JNK 
JNK 
83
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Phosphorylated Bim removes ____ from the mitochondrial outer membrane leading to Bax-induced apoptosis. 

aspartate 

AMP

UCP1  

DHAP 

 ETS 

glycerol 3P 

butyrate

malate 

hydrogen peroxide  

 Semiequinoes

superoxide 

peroxiredoxin

thioredoxin 

fructose-2,6-bisphosphate 

Fructose 6-phosphate 

BCl2 

JNK 
BCl2 
84
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The most potent allosteric activator of PFK1 is _____ which acts to directly tetramerize that enzyme. 

aspartate 

AMP

UCP1  

DHAP 

 ETS 

glycerol 3P 

butyrate

malate 

hydrogen peroxide  

 Semiequinoes

superoxide 

peroxiredoxin

thioredoxin 

fructose-2,6-bisphosphate 

Fructose 6-phosphate 

BCl2 

JNK 
fructose-2,6-bisphosphate 

85
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PKA-phosphorylated PFK2 produces the product ____.

aspartate 

AMP

UCP1  

DHAP 

 ETS 

glycerol 3P 

butyrate

malate 

hydrogen peroxide  

 Semiequinoes

superoxide 

peroxiredoxin

thioredoxin 

fructose-2,6-bisphosphate 

Fructose 6-phosphate 

BCl2 

JNK 
Fructose 6-phosphate 
86
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Insulin-stimulated action of PP1 on PFK2 causes it to produce the product ____. 

aspartate 

AMP

UCP1  

DHAP 

 ETS 

glycerol 3P 

butyrate

malate 

hydrogen peroxide  

 Semiequinoes

superoxide 

peroxiredoxin

thioredoxin 

fructose-2,6-bisphosphate 

Fructose 6-phosphate 

BCl2 

JNK 
fructose-2,6-bisphosphate 
87
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Identify in the circle using CAPS: GAPDH 

  

A

B

C

D

E

F

G

H

I

J

K

M

 


Identify in the circle using CAPS: GAPDH



A

B

C

D

E

F

G

H

I

J

K

M

 
M
M
88
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Identify in the circle using CAPS: FAS

   

A

B

C

D

E

F

G

H

I

J

K

M

 


Identify in the circle using CAPS: FAS



A

B

C

D

E

F

G

H

I

J

K

M

 
B
B
89
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Identify in the circle using CAPS: malic enzyme



A

B

C

D

E

F

G

H

I

J

K

M

 
H
90
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 Identify in the square box using lower case letters: gluconolactone

  

a.

b.

c.

d.

e.

f.

g.

h.

i.

k.

m.

n.

o.

p.

r.


 Identify in the square box using lower case letters: gluconolactone



a.

b.

c.

d.

e.

f.

g.

h.

i.

k.

m.

n.

o.

p.

r.
c.
c.
91
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Identify in the square box using lower case letters: OAA

  

a.

b.

c.

d.

e.

f.

g.

h.

i.

k.

m.

n.

o.

p.

r.


Identify in the square box using lower case letters: OAA



a.

b.

c.

d.

e.

f.

g.

h.

i.

k.

m.

n.

o.

p.

r.


o.

  

o.
92
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Identify in the square box using lower case letters: pyruvate

  

a.

b.

c.

d.

e.

f.

g.

h.

i.

k.

m.

n.

o.

p.

r.


Identify in the square box using lower case letters: pyruvate



a.

b.

c.

d.

e.

f.

g.

h.

i.

k.

m.

n.

o.

p.

r.


m.
  

m.
93
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Identify in the circle using CAPS: ACC

  

A

B

C

D

E

F

G

H

I

J

K

M

 


Identify in the circle using CAPS: ACC



A

B

C

D

E

F

G

H

I

J

K

M

 
G
G
94
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Identify in the circle using CAPS: elongase

   

A

B

C

D

E

F

G

H

I

J

K

M

 


Identify in the circle using CAPS: elongase



A

B

C

D

E

F

G

H

I

J

K

M

 
F
F
95
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Identify in the circle using CAPS: desaturase

  

A

B

C

D

E

F

G

H

I

J

K

M

 


Identify in the circle using CAPS: desaturase



A

B

C

D

E

F

G

H

I

J

K

M

 
C
C
96
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Identify in the square box using lower case letters: palmitate

  

a.

b.

c.

d.

e.

f.

g.

h.

i.

k.

m.

n.

o.

p.

r.


Identify in the square box using lower case letters: palmitate



a.

b.

c.

d.

e.

f.

g.

h.

i.

k.

m.

n.

o.

p.

r.
g
g
97
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Identify in the circle using CAPS: HMGCoA reductase

  

A

B

C

D

E

F

G

H

I

J

K

M

 


Identify in the circle using CAPS: HMGCoA reductase



A

B

C

D

E

F

G

H

I

J

K

M

 
J
J
98
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Identify in the square box using lower case letters: malonylCoA

  

a.

b.

c.

d.

e.

f.

g.

h.

i.

k.

m.

n.

o.

p.

r.


Identify in the square box using lower case letters: malonylCoA



a.

b.

c.

d.

e.

f.

g.

h.

i.

k.

m.

n.

o.

p.

r.
i.
i.
99
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Identify in the circle using CAPS: pyruvate carboxylase

  

A

B

C

D

E

F

G

H

I

J

K

M

 


Identify in the circle using CAPS: pyruvate carboxylase



A

B

C

D

E

F

G

H

I

J

K

M

 
D
D
100
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Identify in the square box using lower case letters: HMGCoA

  

a.

b.

c.

d.

e.

f.

g.

h.

i.

k.

m.

n.

o.

p.

r.


Identify in the square box using lower case letters: HMGCoA



a.

b.

c.

d.

e.

f.

g.

h.

i.

k.

m.

n.

o.

p.

r.
r.
r.