major cyclins and cdks of vertebrates

cyclin D1, D2, and D3

cdk partner?

cdk4, cdk6

cyclin E

cdk partner?

cdk2

cyclin A

cdk partner?

cdk2, cdk1 (originally named cdc2)

cyclin B

cdk partner?

cdk1 (originally named cdc2)

where is cyclin D increased? What is another name for it?

increased over G1

“nuclear D1”

where is cyclin E increased? what is another name for it?

increased toward start of cell cycle in G1 and decreases at beginning of S phase

aka “G1/S cyclin”

where is cyclin A increased? what is another name for it?

increased from start of cell cycle in G1 and decreases at metaphase/anaphase checkpoint in M phase

aka “S-cyclin”

where is cyclin B increased? what is another name for it?

increased from beginning of G2 and decreases at the metaphase/anaphase checkpoint in the M phase.

aka “M-cyclin”

what is the one cdk present in budding yeast?

cdk1