Pharmaceutical and Radiopharmaceutical Agents (part3)- Domain3

Dipyridamole- Persantine

Cardiac, vasodilator

2nd or 3rd degree AV block, bronchospasm, hypotension, allergy to aminophylline

0.56 mg/kg over 4 mins

Adenosine

Cardiac, vasodilator

2nd or 3rd degree AV block, bronchospasm, hypotension, allergy to aminophylline

140 ug/kg/min for 6 mins

Dobutamine

Cardiac, ino/chronotropic

tachyarrythmias, aortic stenosis

5 - 10 ug/kg/min for 3 mins then……10 ug/kg/min for 3 mins then……20 ug/kg/min for 3 mins then……30 ug/kg/min. for 3 mins then……40 ug/kg/min for 3 mins

Aminophylline

Cardiac, reduce symptoms

allergies

125 to 250 mg IV

Regadenosn- Lexiscan

Cardiac, vasodilator

2nd or 3rd degree AV block, bronchospasm, hypotension

0.4 mg in 5ml over 10 sec

Captopril

Renal (ACE inhibitor), renovascular hypertension

allergies

25 - 50 mg orally 1 hour prior

Enalaprilat

Renal (ACE inhibitor), renovascular hypertension

allergies

0.04 mg/kg in 10 mL over 5 mins max dose 2.5 mg

Furosemide- Lasix

Renal (Diuretic)

allergies, unable to urinate

20 - 40 mg over 1 -2 mins (0.3 mg/kg)

Insulin

FDG (glucose levels)

allergies or low blood sugar

3 - 7 units prior to injection

Acetazolamide- Diamox

Brain (BBBD)

kidney disease, liver disease or severe lung disease

1 g in 10 mL sterile water over 2 mins

Cholecystokinin- Sincalide, CCK

Hepatobiliary (GBEF)

gallstones?

0.02 ug/kg in 10 mL saline over 60 mins

Morphine

Hepatobiliary (acute/chronic)

0.04 mg/kg in 10 mL saline over 2-3 mins

Cimetidine- Famotidine

Meckel’s (histamine H2-receptor blocker that inhibits pertechnetate secretion by mucin cells)

300 mg/kg

ACD solution

Anticoagulant

500 mL or 750 mL sterile fluid in polyolefin bag

Heparin

RBC’s and WBC’s

2000 units per 50 cc blood

Contrast media (oral and IV)

Used for some CT procedures

known allergies, renal impairment

Lugol’s solution- SSKI

Thyroid

1 drop/kg to max 40 (20 drops twice daily)

Thyroid stimulating hormone- TSH

Lidocaine

Lidocaine (EMLA) cream

Atropine

Recombinant human TSH- Thyrogen

Thyroid

0.9 mg IM for 2 days

Amino acids

Zofran/Emend

Beta Blockers

Boost/Ensure