Anti-Gout
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10 Terms
gout
uric acid build up
Mitotic agents prototype
colchicine (Colcrys)
Mitotic agent MOA
Stops WBC movement into areas with urate crystals
Mitotic agent indications
Acute gout attack, Short-term management
uricosuric agents prototype
probenecid (Benemid), lesinurad (Zurampic) (chronic gout)
uricosuric agents MOA
Inhibits the reabsorption of uric acid in the kidney , Increases uric acid excretion
Xanthine Oxidase Inhibitors prototype
allopurinol (Zyloprim), febuxostat (Uloric)
Xanthine Oxidase Inhibitors MOA
Reduces uric acid production by inhibiting xanthine oxidase, increases excretion of uric acid precursors
what does cox 1 do?
maintains GI health
what does cox 2 do?
plays role in pain and inflammation
Note 
Flashcards (44)