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purpose of amplifier
input signals with peak-to-peak amplitudes of 5-50 uV to equal the full range of the analog-to-digital A-D converter
analog-to-digital (A-D) converter
takes physiological signals and transfers them to a numeral value
amplifier bandpass frequency
0.1-5,000 Hz
amplifier bandpass decibel
-3 dB points
common mode rejection decibel
80 dB (10,000:1)
differential input impedance of amplifier
100 megOhm
noise level of the amplifier must NOT exceed
2 uV rms with the inputs connected to neutral and with a bandpass of 0.1-5,000 Hz
time (horizontal) resolution of averager
20 us/data point or less
LEAST amount of averaging trials
4,000
what range of the A-D converter should the artifact reject % be set to
90-98%
adequate bits of amp resolution at the the A-D converter
8 bits = adequate
preferred bits of amp resolution at the the A-D converter
12
how is excluding artifact-contaminated trials most common achieved
rejecting those trials that exceed the limits of the A-D converter or some adjustable %
minimum # of channels for SSEPs
4
minimum # of channels for BAEPs
2
Gaussian convolution
takes out raw data and creates average
chassis leakage current
current that flows from the equipment to the ground; can flow to the patient if NOT properly grounded
chassis current is present anytime __
the equipment is plugged into an outlet
can you use extension cords/power strips in the OR
no b/c it can increase leakage current
is a direct connect from the pt "ground" to chassis or power line ground allowed to be present
NO
what should be incorporated in order to actively prevent current flow to the pt
isolation amplifier or solid-state current limiter
chassis leakage should be less than __ with ground open (clinical)
300 uA rms
max chassis leakage with ground open (intraoperative)
100 uA rms
max leakage current through patient leads should be __ to ground with 120 VAC applied (power ON)
10 uA rms
max leakage current should be ___ at the patient end of the table when the power line ground is disconnected (power OFF)
50 uA rms
RMS
root mean square
purpose of biomed check before cases
to check leakage current & other safety parameters of equipment
when should chassis leakage check be done
twice a year
biannually
semi-annually = BEST CHOICE
purpose of an isolation amplifier/solid-state current limiter
prevent current from flowing to the patient
isolation transformer
allows an AC signal to be taken from one device and fed into another WITHOUT connecting the two circuits; blocks interference caused by ground loops
grounding system ensure that no __ > than __ can be measured across an impedance of __ between combination of conductive surfaces or grounding conductors
voltage; 20 mV rms; 1000 Ohms
what to do if data is not reproducible
do another set of averages/trials until replication
replication
two or more temporally independent averages
how is replication demonstrated
by consistency of latency and amp measures of EP components recording in:
latency: 1% of total sweep time
amp: 15% of the peak-to-peak amp
purpose of replication
to demonstrate that clinical EP are repeatable and are of neural --> NOT artifactual
ALL Evoked Potential record should have all the following info:
1) pt name, ID number, age, gender
2) date of exam and procedure
3) tech name or initials
4) recording channels
IMPORTANT items to document
- store averaged waveforms
- time of surgical events & procedures
- alerts issued
- anesthetics and drugs, and significant changes in dose
- significant changes in physiological parameters - BP and temp
- maintain documentation along with stored waveforms
- final report filed in pt's chart
normative data
data obtained from a reference population
if normative data is going to used from another lab (9A), what must be done?
- ALL collection parameters must be replicated from the reference data (identical if using someone else's)
- MINIMUM of 20 patients must be run to make sure they fall within the normal distribution
is normative data relied on intraoperatively (11A)
NO
does the pt serve as their own control (11A)
yes
when must baseline values for IOM data be established
following induction of anesthesia but BEFORE any surgical intervention (incision)
may need to be re-established if changes in anesthetic medications or other physiological parameters occur during the case (check with IP first)
when should monitoring begin
before any surgical manipulation of the nervous system
when should monitoring be discontinued
when the surgical procedure is terminated
purpose of SSEPs intraoperaitvely
to assess function of somatosensory pathways during surgical procedures in which the SC, brainstem, or cerebrum are at risk and to localize the sensorimotor cortex
how are peripheral nerves stimulated
transcutaneously using electrodes placed on the skin over the selected nerve
should SSEPs be used continuously during cautery (bovie)
NO
what type of stimulation are SSEPs
cathodal
cathodal stimulation
- neg charged anions (-) flow from cathode --> tissue --> anode
placement of cathode
between anode and first recording site
cathode
neg charged
attracts anions
DEPOLARIZATION
proximal
anode
pos charge
attracts anions
HYPERPOLARIZATION
distal
what is the selection of nerve stimulated to obtain SSEP determined by?
segmental level of the surgical procedure
median nerve SSEP stimulation spinal cord surgery level is above __
C6 (C1-C5)
ulnar nerve SSEP stimulation spinal cord surgery level is above __
C8 (C6-C8)
PTN and PN SSEP stimulation spinal cord surgery level is below __
C8
upper extremity SSEP purpose for lumbar cases
detects peripheral nerve and brachial plexus for ischemia or compression
is UN or median nerve SSEP monitoring better for lumbar cases
ulnar nerve
where should the stimulation unit be isolated
from the main portion of the stimulation circuitry to avoid large current flow to the pt
stimulation type (9D/11B)
monophasic rectangular pulses using constant voltage or constant current (BEST)
is constant current or constant voltage recommended for intraoperative SSEPs
constant current
why should stim parameters be within safe limits
to prevent tissue damage
pulse width (9D/11B)
100-300 us or 0.1-0.3 ms
stimulation rate 9D and 11B
9D: 3-5 Hz
11B: MN = 2-8 Hz, PTN = 2-10 Hz
make sure NOTHING is divisible by 60 Hz
stimulation intensity 9D and 11B
9D: adequate to produce a muscle twitch or motor threshold (not tetany); equalizing peripheral potentials
11B: 30-40 mA; equalizing peripheral potentials
parameters that influence the degree of pain to the waking patient
1) duration of stimulus (100-300 us) --> 300 = MOST painful; 100 us = LEAST painful
2) current density/surface area of the stimulation electrode
3) intensity of stimulation --> decrease stim intensity to motor threshold or decrease # of averages
large stimulators (surface electrodes) are least/most painful?
least painful
larger surface area =?
smaller current density
small stimulators (needle electrodes) are least/most painful?
most painful
smaller surface =?
larger current density
should you decrease stim intensity BELOW motor threshold
NO NEVER
what to do if the patient is uncomfortable in a clinical setting
1) decrease the number of averages (reps)
2) use a larger size stimulator (less current density)
impedance of electrodes must be under __
5 kOhms to minimize discomfort
how many grounds should be placed to avoid a ground loop
1 ground
where is the ground placed
on the stimulated limb to reduce stim artifact; between the cathode of the stimulating electrode and the 1st recording electrode
where is the ground placed for the:
median nerve
PTN
peroneal nerve
MN = forearm
PTN = calf
PN = thigh
should electrodes be wrapped with tape around the limb
NO
stimulation type:
9D
11B
9D: unilateral limb
11B: interleaving (NEVER stimulate at the same time); bilateral asynchronous
bilateral synchronous stimulation
BOTH sides are being stimulated at the same time & could lead to a false negative
false negative
data unchanged but the patient wakes up with a deficit
anodal blocking DOES NOT cause
inverted waveforms
obligate peaks to appear earlier
response to travel distally to the muscles
MN:
cathode
anode
twitch
cathode = between the tends of the palmaris longus and flexor carpi radialis
anode = 2-3 cm distal to the cathode or on the dorsum of the wirst
twitch = abduction of the thumb (1st digit); thenar abductor pollicis brevis
UN:
cathode
anode
twitch
cathode = medial to the palmaris longus, 2 cm proximal to the wrist crease
anode = 2-3 cm distal to the cathode or on the dorsum of the wrist
twitch = flexion of the 4th & 5th digits; hypothenar abductor digiti minimi
PN:
cathode
anode
twitch
cathode = below fibular head
anode = 2-3 distal to the cathode
twitch = plantar eversion of the foot; activates peroneus longus & peroneus brevis
PTN:
cathode
anode
twitch
cathode = midway between the medial border of the achilles tendon and the posterior border or medial malleolus
anode = 2-3 cm distal to cathode
twitch = plantar flexion of the greater toe or cupping of the sole of the foot; activates adductor hallucis
anodal blocking
cathode & anode are switched
results in a lack of a response or reduced amplitude response
more pronounced in peripheral peaks
failure to stimulate is due to:
increase in impedance
salt bridge
limb edema
peripheral neuropathy
variant anatomy
pedal edema
thenar
APB
hypothenar
ADM
median nerve and ulnar nerve ground placement
on the forearm
alternate site for PTN for peripheral neuropathy & below the knee amputation
peroneal nerve
above the knee amputation alternative site
stimulate femoral nerve
PTN responses are less/more consistent & have less/more inter-subject variability?
more consistent; less inter-subject variability
PN responses are less/more consistent & have less/more inter-subject variability?
less consistent; more inter-subject variability
PTN and PN ground placement
stimulated limb
rep rate:
9D
11B
9D: 2-3 Hz for uppers and lowers
11B: uppers (2-3 Hz); lowers (2-10 Hz)
bandpass:
9D
11B
9D: 1-30-3,000 Hz (-6 dB/octave)
11B: 30-1,000 Hz (-3 dB)
analysis time:
9D
11B
9D:
MN = 40 ms
PTN = 60 ms
11B:
MN = 50 ms (40-50 ms)
PTN = 75-100 ms
number of averages:
9D
11B
9D: several hundred to several thousand
- low noise = 2 reps
- high noise = 2+ reps
11B: 250-1000 reps
number of channels (9D/11B)
MINIMUM of 4