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What is digestion?
food breakdown processes in the mouth, stomach, small intestine, and large intestine
Where does food become a bolus?
mouth
Where does food become chyme?
stomach
Where does food become feces?
large intestine
Where does ingestion occur?
mouth only
Where does mechanical breakdown occur?
mouth, stomach, and small intestine
Where does propulsion occur?
mouth and remaining GI tract
Where does digestion occur?
mouth, stomach, small intestine, large intestine
Where does absorption occur?
stomach, small intestine, and large intestine
Where does defecation occur?
large intestine only
What is mechanical breakdown?
physical breakdown of large food particles into smaller particles without altering their chemical composition
What is chemical digestion?
enzyme-driven breakdown of large food particles into smaller particles that can be absorbed into the bloodstream
What are some examples of mechanical breakdown?
mastication (chewing), churning, segmentation
What are some examples of chemical digestion?
salivary amylase, pepsin and hydrochloric acid, pancreatic lipase
What is peristalsis?
adjacent segments of the GI tract that alternately contract and relax
What is segmentation?
non-adjacent segments of the GI tract that alternately contract and relax
Which layer of the alimentary canal responsible for peristalsis?
muscularis externa
What are sphincters?
ring-like muscular valves that contract and relax to regulate food, liquid, and waste passage
What is the peritoneum?
serous membrane that surrounds most abdominopelvic organs
Which layer of the peritoneum lines the external surface of organs?
visceral peritoneum
Which layer of the peritoneum lines the body wall?
parietal peritoneum
What is peritonitis?
inflammation of the peritoneum
What can peritonitis be caused by?
burst appendix
What are mesenteries?
fold in the peritoneum that extends form the dorsal and ventral body walls to most abdominopelvic organs
What is the main function of mesenteries?
suspends intestines from the abdominal wall, keeping them in place to prevent them from twisting ot collapsing
What is the hepatic portal circulation?
system that drains nutrient-rich blood from the digestive organs
How does the hepatic portal circulation drain blood?
from the digestive organs to the liver
What is special about blood from the hepatic portal circulation?
blood is nutrient-rich
What is the mucosa of the alimentary canal?
epithelium, lamina propria, and muscularis mucosa secretes mucous, digestive enzymes, and hormones while absorbing digestive end products
What is the submucosa of the alimentary canal?
areolar connective tissue containing blood / lymphatic vessels, lymphoid follicles, nerves, and glands that provides flexibility and support
What is the muscularis externa of the alimentary canal?
smooth muscle layer containing a circular layer and longitudinal layer that is responsible for peristalsis
What is the serosa of the alimentary canal?
simple squamous epithelium and areolar connective tissue that contains mesenteries
Which is the best description for the esophagus?
stratified squamous epithelium, thick and productive, protection
Which is the best description for the stomach?
simple columnar epithelium, glands and three muscle lasyers, digestion and mixing
Which is the best description for the small intestine?
simple columnar epithelium and microvilli, villi and folds, absorption
Which is the best description for the large intestine?
simple columnar epithelium and goblet cells, no villi and mucous, water absorption
Which are examples of mechanical stimuli?
stretch that activates mechanoreceptors
Which are examples of chemical stimuli?
pH, nutrients, and solutes that activate chemoreceptors
Which is NOT a hormone that regulates GI tract acitivty?
oxytocin
Where does gastrin secreted from and where does it act upon?
released by the stomach, stimulates acid production in the stomach and defecation
Where do CCK and secretin secrete from and where do they act upon?
released by the duodenum, inhibit stomach secretions and stimulate liver / pancreas secretions
Which branch of the ANS inhibits stomach functions?
symphathetic fibers
Which branch of the ANS stimulates stomach functions?
parasympathetic fibers
What are short reflexes?
intrinsic stimuli that act within the GI wall
What are long reflexes?
extrinsic stimuli that act through the CNS
Which two subdivisions of the nervous ssytem from inputs for long reflexes?
peripheral nervous system (PNS) and autonomic nervous system (ANS)
Which digestive processes occur in the mouth?
ingestion, mechanical breakdown, propulsion, and digestion
What is the lingual frenulum?
fold of mucous membrane that anchors the tongue to the oral cavity floor
Which epithelial tissue type lines the mouth?
stratified squamous epithelium
What are the 3 salivary glands?
parotid, submandibular, and sublingual
What are the functions of saliva?
dissolves food chemicals for taste, moistens / compacts food into bolus, and begins breakdown of starch
What is the pH of saliva?
slightly acidic
How many deciduous (baby) teeth are there?
20
How many permanent (adult) teeth are there?
32
Which classification of teeth are specialized to cut?
incisors
Which classification of teeth are specialized to tear and pierce?
canines
Which classification of teeth are specialized to grind and crush?
premolars
Which classification of teeth are the best grinders?
molars
What are the wisdom teeth?
third molars
When does heartburn occur?
when the stomach acid regurgitates into the esophagus
Which epithelial tissue type lines the pharynx and esophagus?
stratified squamous epithelium
What is chyme?
acidic slurry of ingested food formed in the stomach
What is the pyloric valve?
valve that controls stomach emptying
Which digestive processes occur in the stomach?
mechanical breakdown, propulsion, digestion, absorption
What can be absorbed in the stomach?
only alcohol and aspirin
What is the pH of gastric juice?
highly acidic
Which 4 cells are found in gastric pits?
mucous cells, parietal cells, chief cells, enteroendocrine cells
What do mucous cells in gastric pits secrete?
cloudy, alkaline mucus
What do parietal cells in gastric pits secrete?
hydrochloric acid (HCl) and intrinsic factor
What do chief cells in gastric pits secrete?
pepsinogen and lipases
What do enteroendocrine cells in gastric pits secrete?
paracrines, hormones, and gastrin
What is the function of gastrin?
stimulates the stomach to secrete hydrochloric acid (HCl)
Which type of cells secrete gastrin?
G-cells
Where are G-cells located?
pyloric antrum of the stomach (smaller amounts in duodenum)
What are the 3 phases of gastric activity?
cephalic phase, gastric phase, and intestinal phase
What is the source of control for the cephalic phase of gastric activity?
central nervous system (CNS) control
What is the source of control for the gastric phase of gastric activity?
intrinsic control
What is the source of control for the intestinal phase of gastric activity?
intestinal control
What is the falciform ligament?
strip of mesentery that attaches the liver to the ventral body wall
What is hepatitis?
general inflammation of the liver
What is cirrhosis?
progressive, chronic liver inflammation
What are common causes of hepatitis?
viral infection, drug toxicity, and wild mushroom poisoning
What are common causes of cirrhosis?
chronic hepatitis and alcoholism
What is bile?
fat emulsifier secreted by the liver into the duodenum through ducts
What type of molecule is broken down by bile?
large fat droplets into smaller droplets
What are acini?
clusters of acinar cells that secrete pancreatic juice
What is the pH of pancreatic juice?
8
What does the gallbladder do?
stores and concentrates bile
What are gallstones?
crystalized cholesterol
Which duct does bile exit the liver?
common hepatic duct
Which duct does bile exit the gallbladder?
cystic duct
Which segment of the intestines do the hepatic and pancreatic ducts connect?
duodenum
Where are proteases activated?
duodenum
How do inactive proteases protect the pancreas?
prevent enzymes from destroying pancreatic tissue
What are the 3 segments of the small intestine?
duodenum, jejunum, and ileum
What are vili?
folds that increase surface are
What are microvilli?
finger-like projections that increase surface area
What do intestinal crypts do?
make intestinal juices and contain enteroendocrine cells
Where are intestinal crypts located?
between the villi
What are lacteals?
lymphatic capillaries that absorb and drain fats