cancer
A malignant tumor of potentially unlimited growth that expands locally and systemically.
Risk Factors
Something which increases risk or susceptibility.
Diagnostic Imaging
Technologies that doctors use to look inside your body for clues about a medical condition; includes X-rays, CT scans, nuclear medicine scans, MRI scans and ultrasound
X-rays
To examine, treat, or photograph with X-rays.
CT scans
A sectional 3-dimensional view of the body constructed by computed tomography.
MRI
A noninvasive diagnostic technique that produces computerized images of internal body tissues and is based on nuclear magnetic resonance of atoms within the body induced by the application of radio waves.
Radiology
A branch of medicine concerned with the use of radiant energy (as X-rays or ultrasound) in the diagnosis and treatment of disease.
Osteosarcoma
A cancer derived from bone or containing bone tissue.
Bone scans
A test that detects areas of increased or decreased bone metabolism; test is performed to identify abnormal processes involving the bone such as tumor, infection, or fracture.
Cell Cycle
An ordered sequence of events in the life of a eukaryotic cell, from its origin in the division of a parent cell until its own division into two.
Apoptosis
The changes that occur within a cell as it undergoes programmed cell death, which is brought about by signals that trigger the activation of a cascade of suicide proteins in the cell destined to die.
Oncogenes
A gene having the potential to cause a normal cell to become cancerous.
Biopsy
The removal and examination of tissue, cells, or fluids from the living body
Proto-oncogenes
A normal cellular gene corresponding to an oncogene; a gene with a potential to cause cancer but that requires some alteration to become an oncogene.
Carcinomas
the most common types of cancer, arise from the cells that cover external and internal body surfaces. Lung, breast, and colon are the most frequent cancers of this type in the United States.
Sarcomas
cancers arising from cells found in the supporting tissues of the body such as bone, cartilage, fat, connective tissue, and muscle
Lymphomas
cancers that arise in the lymph nodes and tissues of the body’s immune system
Leukemias
cancers of the immature blood cells that grow in the bone marrow and tend to accumulate in large numbers in the bloodstream.
DNA microarray
A microarray of immobilized single-stranded DNA fragments of known nucleotide sequence that is used especially in the identification and sequencing of DNA samples and in the analysis of gene expression (as in a cell or tissue).
DNA replication
Before a cell divides, the cell makes a copy of its DNA through a process
Invasion
the direct migration and penetration by cancer cells into neighboring tissues
metastasis
the ability of cancer cells to penetrate into lymphatic and blood vessels, circulate through the bloodstream, and then invade healthy tissues elsewhere in the body
benign tumors
tumors that cannot spread by invasion and metastasis
malignant tumors
tumors that are capable of spreading by invasion and metastasis
metastatic melanoma
cancer cells in the liver
tumor suppressor gene
codes for proteins that slow down cell growth and division
p53
a protein that tumor supressor gene codes for that can trigger cell suicide.