Industrial Biotechnology

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11 Terms

1
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What are the different designs of bioreactors?

2
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Commercial Lab-scale CSTRs

  • control tower

  • reactor and everything on balances

3
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How to select a reactor type?

  • oxygen

  • density

4
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Basic considerations in bioreactior and bioprocess design

  • What is the product?

  • How much does the product cost?

  • What is the production cost?

5
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Factors contributing to the production costs

  • R&D

  • reactor building

  • raw materials and media

  • upstream operation (labor, energy, water, waste disposal, depreciation insurance) 20%

  • downstram processing 70-80%

6
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baffles

min. 4 vertical bars near walls of reactor to create turbulent flow to aid with mixing

7
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Why is mixing needed?

8
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Which geometry is best for a CSTR mixing?

9
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The different patterns of gas ditribution, and the best one

impeller flooding

impeller loading

complete gas dispersion

  • too fast an impeller speed can break cells

10
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Power number

11
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Reynold’s number