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Tissue
a group of cells that work together to perform a common function
Four major tissue types
Epithelial tissue
covering and lining of the body
Connective tissue
bone and cartilage
Muscle tissue
movement
Nerve tissue
communication and coordination
Epithelial tissue
highly cellular
little or no intercellular space
highly regenerative (mitosis)
avascular
avascular
little blood vessels
Connective Tissue
lots of intercellular space
ability to produce fiber to plug
up holes = fibrosis —> repair process
Free apical surface
faces lumen or external surface
cilia
microvilli
Cilia
hair-like projections for movement
Microvilli
fingerlike extensions of the cell membrane which increase surface
Lateral adherences
structures which hold cells together
Types of lateral adherences
Right junctions
Desmosomes
Gap junctions
Tight junctions
protein that links cells together which are impermeable
example: stomach, urinary bladder
Desmosomes
protein attached cells that allow the cells to stretch without separating
example: cells of the heart
Gap junctions
protein attaching cells that allows communication between the cells
example: nerve impulse
allows passage between cells
Basal surface
(with basement membrane)
regulates what passes
Three epithelial cell shapes
squamous cells
cuboidal cells
columnar cells
Squamous cells
flat, scale like
Nucleus looks like a flattened disc
allows for rapid passage of substances
Cuboidal cells
about as tall as it is wide; boxlike
Nucleus is spherical
many have microvilli
function in secretion or absorption
Columnar cells
taller than they are wide
Nucleus is elongated top to bottom
many have cilia or microvilli
specialized function for secretion and absorption
Type of epithelial layers
Simple
Stratified
“Simple” means. . .
simple layer
“Stratified” means. . .
multiple layers
named by apical cell shape
Types of simple epithelia
Simple squamous epithelium
Simple cuboidal epithelium
Simple columnar epithelium
Pseudostratified columnar epithelium
Types of Stratified Epithelia
Stratified squamous
Stratified columnar
Stratified cuboidal
Transitional epithelium
Simple squamous epithelium
flattened cells and found in the lungs
lines body cavities and vessels
alveoli of lungs
Simple cuboidal epithelium
single layer, tall as they are wide
found in ducts
vertebrate kidneys and glands
Simple columnar epithelium
single layered, taller than they are wide
lines the digestive tract (SI, LI)
Pseudostratified columnar epithelium
“pseudo” = false
“stratified” = multiple layers
gives us a false appearance of having multiple layers because the nucleus is of different heights
respiratory tract (trachea)
Stratified squamous epithelium
protective, multiple layers with flat apical cells
skin, mouth, and esophagus
epidermis of birds, reptiles
shed molting in snakes
Stratified columnar epithelium
multi-layer surface that is columnar
rare
found in pharynx, white of eye, and salivary gland duct
Stratified cuboidal epithelium
multiple layer and cuboidal shape
found in glands of vertebrates and epidermis of some salamanders
Transitional epithelium
can appear squamous or cuboidal
found in bladder and ducts of urinary system
can change shape from the state of organ
usually deals with piss
Glandular epithelia
specialized to secrete product
Types of glandular epithelia
Endocrine
Exocrine
Merocrine glands
Holocrine glands
Exocrine
glands with ducts that collect and carry product away from gland
Endocrine
secrete product into extracellular fluid and is transported by the circulatory system
Functional Classification of Epithelial
Sensory
Germinal
Cuticular
Glandular
Sensory epithelial cells
modified epithelial cells that detect changes in the environment
Germinal epithelial cells
found in ovary and seminiferous tubules
Cuticular epithelial cells
outermost layer of dead protective skin
Glandular epithelial cells
secretes sweat, mucus, and enzymes
Four Categories of Connective Tissue
connective tissue proper
cartilage
bone
liquid (or blood)
“Fibro” means. . .
connective tissue proper
“Blast” means. . .
immature cell
makes matrix
responsible for making specialized cells
“cyte” means. . .
mature cells that maintain the matrix