Alpha and Beta Receptor Antagonists Lecture

Foundations Exam 2

Where do beta 1 receptors work?

Heart

What do beta 1 receptors do?

Increase heart rate

Where do beta 2 receptors work?

Smooth muscle

What do beta 2 receptors do?

Relaxation, peripheral vasodilation

What do alpha 1 receptors do?

Vasoconstriction

Which beta blockers exhibit alpha blocking properties? (mixed)

Labetalol and Carvedilol

Where do alpha 1 receptors work?

Blood vessels

What are the contraindications for beta blockers?

2nd or 3rd degree AV block, cardiogenic shock, be careful with diabetes

How preferred are beta blockers for hypertension?

2nd line for hypertension alone

How preferred are alpha blockers for hypertension?

Used for resistant hypertension, more often for benign prostate hyperplasia + off-label indications

What systems have side effects associated with amiodarone?

Lungs, Thyroid, Eyes, GI, Heart, Skin, Liver

What does the iodine moiety cause in amiodarone?

Adverse thyroid side effects