Chapter 6 - DNA Replication, Repair, and Recombination

If a stretch of DNA on the parental strand of a replicating chromosome has the sequence 5'-AGCTCGATCGGCTA-3', what will the sequence of the newly synthesized strand made from this stretch of template be?

3'-TCGAGCTAGCCGAT-5'

What is the name of the DNA sequence where replication begins?

replication origin

The sequence at which DNA replication begins tends to have which characteristic?

AT-rich

In which direction, and on which strands does DNA replication proceed from a replication origin on a chromosome?

in both directions, on both strands

The bonds that link 2 DNA strands together are ...

hydrogen bonds

The energy for the polymerization reaction in DNA synthesis is powered by ...

the breaking of high-energy phosphate bonds in the deoxynucleotides.

How does polymerase help maintain the accuracy of DNA replication?

DNA polymerase can cut out improperly base-paired nucleotides and add the correct one during synthesis

How are the primers from which DNA synthesis starts different from the DNA itself?

the primers are made up of RNA not DNA

What is the name of the enzyme that fills the sequence gaps after primers are removed from a newly synthesized DNA strand?

repair polymerase

What is the name of the protein that binds the 2 separated DNA strands to keep them from base pairing again before they can be replicated?

single-strand binding protein

What is the function of a topoisomerase in DNA replication?

it relieves the tension in DNA strands

Which strand of DNA will telomerase elongate?

the template of lagging strand