this is NOT everything, just the main points bruv
how the brain registers all pleasures the same way
releasing dopamine in the nucleus accumbens (pleasure center)
ways 2 do drugz
smoking/injecting faster & stronger dopamine signal
swallowing pills
neurotransmitter that dopamine interacts with
dopamine interacts with NT glutamate
meow
meow
SUD characteristics
Loss of control
participation in use despite family/work/health problems w/ a tendency to relapse
cravings increase risk of relapse
SUD risk factors
genetics
chronic stress (socioeconomic factors)
Hx of trauma, abuse, combat experience
low self esteem
low pain tolerance
low success
risk taking tendencies
cultural consids
Alaska natives/Native americans have high % of aud
Asian groups have a lower % of aud
Metabolism of alcohol differs btwn cultures
older adults can have new onset of AUD/SUD due to loss of partner/family & social isolation
ROS/subjective changes
blackout/LossOC
severe WtL/WtG
trauma
sleep problems
chronic pain
accidents
bowel movement changes with drugs
opioids: constipation
etoh: bright/dark red blood (rectal bleeding)
screening tools
CAGE
AUDIT self-report
SBIRT
CIWA-Ar