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Chromosomes
Where most genetic material is stored
Diploid
2 sets of chromosomes; most animals (and humans) have this
Homologous Chromosomes
Two chromosomes of the same type
Gene
Segment of DNA that determines an inherited trait; encode proteins, which determine our inherited traits
Alleles
Different versions of the same gene; can be dominant or recessive with dominant as uppercase and recessive as lowercase
Genotype
Homozygous Dominant (2 dominant), Homozygous Recessive (2 recessive), and Heterozygous (2 different alleles)
Phenotype
Describes appearence of a genotype
Gametes
Get one copy of each gene
Mutations
A change in DNA sequence; most genetically inherited disorders are caused by mutations; can produce damaged protein that does not function properly
Somatic Cells
Body cells (all cells that are not germ line cells)
Germ Line Cells
Give rise to gametes (egg and sperm); mutations in these cells are passed to offspring
Pedigree
Insight into the inheritance pattern of a genetically inherited condition
Autosomal Recessive/Dominant
Location of mutated allele; most affected individuals have parents who are unaffected but are carriers of the mutated allele
X-linke
Females have two X chromomsomes nad have two gene copies for genes on the X chromosome; males have one X chromosome and have only one copy for genes on the X chromosome
Changes in Chromosome Number
Changes in chromosome number occurs when chromosomes don’t separate properly during gamete formation; there are only 5 changes in chromosome number that are compatible with life