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Antimicrobials
substances that kill or suppress the growth or multiplication of microorganisms used to inhibit bacteria and sometimes protozoa.
Narrow-spectrum antibiotics
Active against single or limited group of microorganisms
Extended-spectrum antibiotics
Effective against gram positive organisms and a signifanct number of gram negative microorganisms.
Broad-spectrum antibiotics
Acts against a wide variety of species
Bacteriostatic drugs
Limit the spread of infection by halting bacterial growth and replication.
Bactericidal drugs
Act independently of host immune defenses to cause cell death.
Prophylactic
Use of antimicrobials to prevent an infection
Empiric
Initial use of broad-spectrum antibiotic especially if px is seriously ill
Definitive
Following culture and susceptibility tests. Narrow in spectrum agent to target specific pathogen
Penicillin
inhibition of cell wall synthesis
Clindamycin
Inhibition of protein synthesis
Penicillin
The drug of choice assuming px does not have allergies. The standard antibiotic
Natural, semi-synthetic, B- lactamase inhibitors
Penicillin classification
Penicillin G
Discovered by Alexander Fleming
Penicillin V
Has a chemical structure that enhances stability in acidic environments. Administered orally
Amoxicillin
Replaced penicillin VK as the drug of choice for prevention of infective endocarditis. Produces higher and longer sustained blood levels
Co-amoxiclav
combination of amoxicillin and clavulanate
Clindamycin
Both bacteriostatic and bactericidal
Metronidazole
Inhibits acetaldehyde enzymes
Metronidazole
active against anaerobic bacteria
Fluroquinalones
bactericidal antibiotics with broad-spectrum activity
Nystatine
topical antifungal
Ampothericine B
Antifungal medication given if px if infected systematically
Acyclovir
10 times more potent against herpes virus
Valacyclovir
FDA approved for children 12 years and older for tx of herpes labialis and 2 years and older for chickenpox.
RX
latin for recipe
Subscription
instructions given to the pharmacist
Transcription
Instruction to px
Superscription
Contains name of the dentist, address and contact number
Gram staining
Test whether gram is positive or negative
Positive: Blue
Thick cell wall
Negative: Pink
Thin cell wall
Crystal Violet
V
Iodine
I
Ethyl Alcohol
A
Safranin
S
Morbidity
A diseased state, disability or poor health due to any cause
Mortality
Emergencies that may threaten the px’s life or state of being subject to death
Oxygen
Primary emergency drug in the dental office
Hypoxemia
low oxygen content in the arterial blood
Albuterol
Tx of bronchospasm in either asthma attack or allercgic reaction
Aspirin
Tx for suspected acute coronary syndrome (heart attack)
Diphenhydramine
Tx for allergic reactions
Epinephrine
Tx for anaphylaxis, severe persistent asthma and bronchospasm
Glucose(oral)
Tx for hypoglycemia
Midazolam
Anticonvulsant for status epilepticus
Naloxone
reverses opioid medications
Nitroglycerine
Tx for chest pain as a result of angina pectoris
Flumazenil
Reverses oversedation
Position
Circulation
Airway
Breathing
Definitive Treatment
Five basic steps for management of medical emergencies
2-2.4
Compression depth in adults
2
compression depth in children
1.5
compression depth in infants
30:2
compression to ventilation ratio for adults
15:2
compression to ventilation ratio for children
Tongue
Most common cause of airway obstruction
Glossoptosis
tongue is relaxed causing airway obstruction
Penicillin and latex
primary agents that provoke allergic reactionsw
Allergy
hypersensitivity response by the immune system to antigens that are recognized as foreign
Asthma
aka Acute Bronchospasms
IgE
immunoglobulin responsible for allergies
Intrinsic Asthma
asthma caused by stress
Extrinsic Asthma
Asthma triggered by outside causes like dust and pollen
Hyperventilation
A maladaptive anxiety reaction that occurs in apprehensive pxs who attempt to hide their anxiety
Syncope
Most common medical emergency in the dental office
Vasopressor syncope / Simple faint
most common type of syncope
Dental Caries
Most prevalent chronic disease
White spot lesion
Earliest sign of dental caries
Saliva
Acts as a buffer for caries
White spot lesion
Found on the enamel smooth surfaces. best seen after tooth surface is cleaned and air dryed
Streptococcus Mutans
contribute to dental caries because of their ability to adhere, produce and survive.
S. Mutans
most common in man with over 98% of adults harboring this bacterium
Sucrose
factor affecting dental caries prevalence and progression
Frequency of sugar consumption
Intensity of caries in children may be due to
pH below 5.5
an environment for bacterial growth
Fluoridation
Placement of fluoride in the water
Fluoridization
Placement of fluoride done by the dentist
Disclosing tablet or solution
helps the child and parent evaluate the thoroughness of the cleaning
Children under 3 years old
should brush with a smear of fluoride toothpaste to prevent fluorosis
Children over 3 years old
should brush with a pea sized amount to prevent fluorosis
Prevent decay on intact dental surfaces
Arrest active decay
Remineralize decalcified tooth surfaces
Goals of fluoride administration
Fluoride
Inhibits demineralization and promotes remineralization
Silver diamine fluoride
A topical fluoride that contains 5% fluoride, 24-27% silver
0.7-1.2 ppm
Normal fluoride
Period of ovum
Fertilization to implantation, 10-14 days
Period of embryo
Cell differentiation, major organs appear. 2-8 weeks
Period of fetus
maturation of newly formed organs 8-40 weeks
50%, 200%
most children undergo _ increase in length and _ increase in weight
Gorss motor skills
By age 2 a child has _ to run, climb walk up and down stairs
8th week
Palatal fusion occurs at
9th week
Cleft palate occurs at
Osteoblasts
Bone forming cells
Osteoclasts
Bone destroying cells
Fontanels
Bones that compose the cranium are not fused and are separated by gaps called
2 years
gaps close by ossification within _ after birth
Ectoderm and Mesoderm
Germ layers
Ectoderm
responsible for future enamel
Mesoderm
responsible for future pulp and dentin
Dental organ
formative tissue of enamel
Dental papilla
formative tissue of dentin and pulp