Pediatric Dentistry SAS 9-13

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Antimicrobials

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140 Terms

1

Antimicrobials

substances that kill or suppress the growth or multiplication of microorganisms used to inhibit bacteria and sometimes protozoa.

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2

Narrow-spectrum antibiotics

Active against single or limited group of microorganisms

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3

Extended-spectrum antibiotics

Effective against gram positive organisms and a signifanct number of gram negative microorganisms.

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4

Broad-spectrum antibiotics

Acts against a wide variety of species

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5

Bacteriostatic drugs

Limit the spread of infection by halting bacterial growth and replication.

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6

Bactericidal drugs

Act independently of host immune defenses to cause cell death.

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7

Prophylactic

Use of antimicrobials to prevent an infection

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8

Empiric

Initial use of broad-spectrum antibiotic especially if px is seriously ill

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9

Definitive

Following culture and susceptibility tests. Narrow in spectrum agent to target specific pathogen

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10

Penicillin

inhibition of cell wall synthesis

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11

Clindamycin

Inhibition of protein synthesis

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12

Penicillin

The drug of choice assuming px does not have allergies. The standard antibiotic

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13

Natural, semi-synthetic, B- lactamase inhibitors

Penicillin classification

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14

Penicillin G

Discovered by Alexander Fleming

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15

Penicillin V

Has a chemical structure that enhances stability in acidic environments. Administered orally

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16

Amoxicillin

Replaced penicillin VK as the drug of choice for prevention of infective endocarditis. Produces higher and longer sustained blood levels

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17

Co-amoxiclav

combination of amoxicillin and clavulanate

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18

Clindamycin

Both bacteriostatic and bactericidal

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19

Metronidazole

Inhibits acetaldehyde enzymes

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20

Metronidazole

active against anaerobic bacteria

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21

Fluroquinalones

bactericidal antibiotics with broad-spectrum activity

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22

Nystatine

topical antifungal

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23

Ampothericine B

Antifungal medication given if px if infected systematically

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24

Acyclovir

10 times more potent against herpes virus

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25

Valacyclovir

FDA approved for children 12 years and older for tx of herpes labialis and 2 years and older for chickenpox.

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26

RX

latin for recipe

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27

Subscription

instructions given to the pharmacist

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28

Transcription

Instruction to px

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29

Superscription

Contains name of the dentist, address and contact number

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30

Gram staining

Test whether gram is positive or negative

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31

Positive: Blue

Thick cell wall

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32

Negative: Pink

Thin cell wall

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33

Crystal Violet

V

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34

Iodine

I

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35

Ethyl Alcohol

A

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36

Safranin

S

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37

Morbidity

A diseased state, disability or poor health due to any cause

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38

Mortality

Emergencies that may threaten the px’s life or state of being subject to death

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39

Oxygen

Primary emergency drug in the dental office

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40

Hypoxemia

low oxygen content in the arterial blood

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41

Albuterol

Tx of bronchospasm in either asthma attack or allercgic reaction

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42

Aspirin

Tx for suspected acute coronary syndrome (heart attack)

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43

Diphenhydramine

Tx for allergic reactions

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44

Epinephrine

Tx for anaphylaxis, severe persistent asthma and bronchospasm

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45

Glucose(oral)

Tx for hypoglycemia

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46

Midazolam

Anticonvulsant for status epilepticus

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47

Naloxone

reverses opioid medications

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48

Nitroglycerine

Tx for chest pain as a result of angina pectoris

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49

Flumazenil

Reverses oversedation

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50

Position

Circulation

Airway

Breathing

Definitive Treatment

Five basic steps for management of medical emergencies

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51

2-2.4

Compression depth in adults

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52

2

compression depth in children

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53

1.5

compression depth in infants

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54

30:2

compression to ventilation ratio for adults

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55

15:2

compression to ventilation ratio for children

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56

Tongue

Most common cause of airway obstruction

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57

Glossoptosis

tongue is relaxed causing airway obstruction

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58

Penicillin and latex

primary agents that provoke allergic reactionsw

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59

Allergy

hypersensitivity response by the immune system to antigens that are recognized as foreign

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60

Asthma

aka Acute Bronchospasms

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61

IgE

immunoglobulin responsible for allergies

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Intrinsic Asthma

asthma caused by stress

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63

Extrinsic Asthma

Asthma triggered by outside causes like dust and pollen

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64

Hyperventilation

A maladaptive anxiety reaction that occurs in apprehensive pxs who attempt to hide their anxiety

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65

Syncope

Most common medical emergency in the dental office

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66

Vasopressor syncope / Simple faint

most common type of syncope

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67

Dental Caries

Most prevalent chronic disease

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68

White spot lesion

Earliest sign of dental caries

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69

Saliva

Acts as a buffer for caries

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70

White spot lesion

Found on the enamel smooth surfaces. best seen after tooth surface is cleaned and air dryed

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71

Streptococcus Mutans

contribute to dental caries because of their ability to adhere, produce and survive.

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72

S. Mutans

most common in man with over 98% of adults harboring this bacterium

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73

Sucrose

factor affecting dental caries prevalence and progression

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74

Frequency of sugar consumption

Intensity of caries in children may be due to

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75

pH below 5.5

an environment for bacterial growth

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76

Fluoridation

Placement of fluoride in the water

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77

Fluoridization

Placement of fluoride done by the dentist

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78

Disclosing tablet or solution

helps the child and parent evaluate the thoroughness of the cleaning

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79

Children under 3 years old

should brush with a smear of fluoride toothpaste to prevent fluorosis

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80

Children over 3 years old

should brush with a pea sized amount to prevent fluorosis

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81

Prevent decay on intact dental surfaces

Arrest active decay

Remineralize decalcified tooth surfaces

Goals of fluoride administration

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82

Fluoride

Inhibits demineralization and promotes remineralization

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83

Silver diamine fluoride

A topical fluoride that contains 5% fluoride, 24-27% silver

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84

0.7-1.2 ppm

Normal fluoride

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85

Period of ovum

Fertilization to implantation, 10-14 days

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86

Period of embryo

Cell differentiation, major organs appear. 2-8 weeks

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87

Period of fetus

maturation of newly formed organs 8-40 weeks

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88

50%, 200%

most children undergo _ increase in length and _ increase in weight

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89

Gorss motor skills

By age 2 a child has _ to run, climb walk up and down stairs

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90

8th week

Palatal fusion occurs at

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91

9th week

Cleft palate occurs at

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92

Osteoblasts

Bone forming cells

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93

Osteoclasts

Bone destroying cells

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94

Fontanels

Bones that compose the cranium are not fused and are separated by gaps called

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95

2 years

gaps close by ossification within _ after birth

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96

Ectoderm and Mesoderm

Germ layers

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97

Ectoderm

responsible for future enamel

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98

Mesoderm

responsible for future pulp and dentin

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99

Dental organ

formative tissue of enamel

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100

Dental papilla

formative tissue of dentin and pulp

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