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neurons
receive and transmit information
CAN transport over long distances
glia
exchange chemicals with adjacent neurons
CANNOT transport over long distances
membrane
two layers of fatty phosolipids
small uncharged molecules that can move freely across the membrane
water (h20), oxygen (02), carbon dioxide (CO2)
charged ions need protein channels to pass through the membrane
sodium (Na), potassium (K), calcium (Ca), chloride (Cl)
4 major structures that compose a neuron
dendrites: branching fibers, information receiver
axon: information sender
soma: cell body; contains nucleus, ribosomes, mitochondria
presynaptic terminals: axon releases chemicals here that cross from one neuron to another through the synaptic gap
afferent axons
bring information INTO the structure; sensory neurons
efferent axons
send information AWAY from the structure; motor neurons
sensory neurons
send messages from the skin and senses TO the brain
motor neurons
sends messages from the brain OUT to the muscles
interneurons
work in the spinal cord and brain to help process/transmit information
nucleus
structure that contains chromosomes
mitochrondria
powerhouse of the cell
ribosomes
site of protein synthesis in the cell
endoplasmic reticulum
network of thin tubes that transport newly synthesized proteins to other locations
myelin sheath
covering found on some axons that insulates the axon and increases the speed of transmission
Nodes of Ranvier
interruptions in the myelin sheath that facilitate rapid conduction
saltatory conduction
jumping of action potentials from node to node
astrocyte
star shaped; wrap around synaptic terminals of axons; helps synchronize the activity of axons enabling them to send messages in wave; removes waste materials when neurons die
olgodendrocytes
surrounds and insulates certain axons in the brain and spinal cord; builds myelin sheaths around the brain and spinal cord
schwan cells
surround and insulates certain axons in the periphery of the body; builds myelin sheaths around axons in the periphery of the body
radial glia
guides migration of neurons; guides growth of axons and dendrites during embryo development
micro glia
proliferate in areas of brain damage; removes toxic materials
blood brain barrier
keeps out viruses, bacteria, and harmful chemicals; uncharged and lipid soluble molecules can cross
active transport
protein mediated process that pumps useful things from the blood into the brain
concentration gradient
sodium 10x more concentrated outside the membrane
potassium 20x more concentrated inside the membrane
sodium potassium pump
ACTIVELY transports 3Na out and 2K in
synapse
gap between two neurons where communication occurs; sherrington
temporal summation
several impulses from one neuron over time
spatial summation
impulses from several neurons at separate locations at the same time
glutamate and GABA
glutamate: excitatory
GABA: inhibitory, puts the brakes on
trytophan
precursor to serotonin in the brain, makes you tired
ionotropic
attachment causes immediate opening of an ion gate
metabotropic
relies of second messenger, alters receptor protein
affinity
how strongly a drug binds to a receptor
efficacy
tendency of a drug to activate a receptor
Bell-Mengendie Law
sensory neurons enter on the DORSAL side
motor neurons exit on the VENTRAL side
meninges
membrane surrounding the brain and spinal cord
cerebral spinal fluid
cushions the brain
provides buoyancy
provides hormones to the brain and spinal cord
provides nutrition for the brain and spinal cord
hydrocephalus
obstruction of cerebral spinal fluid flow
law of specific nerve endings
any impulse in a given nerve sends the same kind of message to the brain
fovea
center of most precise vision
rods
black/white vision
faint light
most abundant in the periphery of the retina
cones
color vision
bright light
most abundant around/in the fovea
young-hemholtz theory (trichromatic)
3 kinds of cones...long wavelengths are red, short are blue, medium are green
opponent-process theory (hering)
we perceive color in terms of paired opposites (red vs green, yellow vs blue, white vs black) 3 receptor complexes
retinex theory (color constancy, edwin land)
information from the retina reaches the cortex and the cortex compares brightness and color perception for each area
myopia
nearsightedness
hyperopia
farsightedness
presbyopia
difficult to focus up close
astigmatism
blurring of lines in one direction; asymmetric curvature of the eyes
color-vision deficiency
inability to perceive color differences
color blindness
inability to perceive anything but shades of black and white
motion blindness (akinetopsia)
failure to detect that an object is moving
visual agnosia
inability to recognize objects
prosopagnosia
inability to recognize faces
lazy eye (amblyopia ex anopsia)
ignores vision in one eye
strabismus
eyes don't point in the same direction or focus on the same thing
average adult can hear
15-20,000Hz
pinna
outer ear; helps locate sound
tympanic membrane (ear drum)
vibrates at same frequency as the sound wave
parts of tympanic membrane
hammer (malleus), anvil (incus), stirrup (stapes)
oval window
membrane from middle ear to the cochlea in the inner ear
cochlea
snail shaped tubes:
scala vestibuli
scala media
scala tympani
frequency theory
basilar membrane vibrates in synchrony with sound, producing action potentials at the same frequency
place theory
sound causes one location along the basilar membrane to resonate: string on a piano
volley principle
volleys of responses by many auditory neurons
amusia
tone deafness:
cannot detect changes in pitch
cannot recognize tunes
thinks everyone sings beautifully
absolute pitch
ability to hear a note and identify it
genetics but also early music training
cortical motion deafness
hears sound but unable to tell that it is moving
conductive deafness
middle ear deafness, can hear themselves clearly
nerve deafness/inner ear deafness
damage to cochlea, hair cells, basilar membrane, or auditory nerve
tinnitus
similar to phantom limb
frequent ringing in their ears
damage to nerve endings
caused by loud noise, extra earwax, stiffening of inner ear bones
james-lange theory
physiological response comes before emotion
cannon-bard
physiological response and emotion occur simultaneously
schacter-singer theory
cognitive appraisal is needed to identify the emotion
old treatment for panic disorder
barbiturates: tranquilizers...habit forming and fatal in overdose (especially when combined with alcohol)
treatment for panic disorder (benzos)
benzodiazepines:
valium (diazapam)
libium (diazepoxide)
xanax (alprazolem)
leukocytes (white blood cells)
key player in the immune syste
b-cells
mature in bone marrow
secrete antibodies (Y-shaped like lock and key)
attach + attack
t-cells
mature in the thymus gland
2 kinds: cytotoxic (attack without secreting antibodies)
helper t-cells: help t or b cells multiply
natural killer cells
blood cells that attack tumor cells
attacks almost all intruders
macrophages
surround intruder and digest it
cover + consume
cytocines
attack infections
communicate with the brain to stimulate anti-illness behavior
stimulates vagus nerve by releasing prostaglandins which effects the hypothalamus and hippocampus
anti-illness behavior
fever
fatigue
sleepiness
lack of appetite
lack of sex drive
aspirin/ibuprofen
decrease fever by inhibiting prostaglandins
psychoimmunology
study of stress on the immune system
prolonged stress has similar symptoms as depression
sleep cycle: stage 1
low breathing
low brain waves
low heart rate
muscles relax
hallucinations
hypnagogic sensations (floating, jerks)
sleep cycle: stage 2
sleep spindles
asleep but easily awakened
sleep cycle: stage 3
transitional stage
sleep cycle: stage 4
deep sleep
hard to awaken
talking in sleep
walking in sleep
sleep cycle: REM
paradoxical sleep
genital arousal
twitching
paralyzed
not easily awakened
internal body is aroused, external is very calm
vivid dreams
locus coeruleus
releases norepinephrine
hypothalamus
releases histamine
hypothalamus (2)
releases orexin + hypocretin
basal forebrain
releases GABA + acetylcholine
endogenous circannual rhythm
annual seasonal changes
endogenous circadian rhythm
daily rhythms
zeitgeber
stimulus for resetting the circadian rhythm
phase-delay
traveling WEST, stay up late and awake already adjusted