Module 7: Treatment and Resistance

antibiotics

compounds produced by one species of microbe that can kill or inhibit the growth of other microbes

antimicrobials

natural antibiotics or synthetic agents

bacteriostatic

reversible effect

inhibits growth of cell division—blocking growth or division

bactericidal

kills bacterial cells

never able to revive

broad spectrum

target many bacteria

narrow spectrum

target specific pathogen

what drugs target cell wall synthesis?

penicillin and vancomycin

transglycosylase

penicillin PBP

what antibiotic affects transcription?

rifamycin

what antibiotic affects protein synthesis?

tetracycline and erythromycin

susceptibility

the bacterium is fully affected by the antibiotic

intermediate susceptibility

the bacterium is slightly affected by the antibiotics

resistance

the bacterium is not affected by the antibiotic

penicillin resistance

alteration of penicillin binding proteins

methicillin resistance

mutation of penicillin binding protein 2