Glucose-UDP synthesis

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8 Terms

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1) Only reversable

Glucose-6-Phosphate is first converted to glucose-1-phosphate

Enzyme: Phosphoglucomutase

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2)

Glucose-1-phosphate is further activated by reacting with UTP to yield UDP-glucose and pyrophosphate

Enzyme: UDP-glucose pyrophosphorylase

PPi is released during this reaction

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PPi → 2 Pi

Enzyme: Inorganic pyrophosphatase

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Glucose-6-phosphate

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Glucose-1-phosphate

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Glucose-1-phosphate + UTP

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UDP-Glucose

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Hydrolysis of pyrophosphate is…

very exergonic and drives the reaction