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1) Only reversable
Glucose-6-Phosphate is first converted to glucose-1-phosphate
Enzyme: Phosphoglucomutase
2)
Glucose-1-phosphate is further activated by reacting with UTP to yield UDP-glucose and pyrophosphate
Enzyme: UDP-glucose pyrophosphorylase
PPi is released during this reaction
PPi → 2 Pi
Enzyme: Inorganic pyrophosphatase
Glucose-6-phosphate

Glucose-1-phosphate

Glucose-1-phosphate + UTP

UDP-Glucose

Hydrolysis of pyrophosphate is…
very exergonic and drives the reaction