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Biology
The scientific study of life
Evolution
any gradual change; the genetic and resulting phenotypic change in populations of organisms from generation to generation
Nucleic acids
a polymer made up of nucleotides, specialized for the storage, transmission, and expression of genetic information; DNA and RNA are nucleic acids
Proteins
a long-chain polymer of amino acids with 20 different common side chains. Occurs with its polymer chain extended in fibrous proteins, or coiled into a compact macromolecule in enzymes and other globular proteins. The component amino acids are encoded in the triplets of messenger RNA, and proteins are the products of genes
Liposomes
a spherical structure contained by a membrane of phospholipids. Can be used to deliver drugs to cells
Prokaryotes
unicellular organisms that do not have nuclei or other membrane-enclosed organelles. Includes Bacteria and Archaea
Bacteria
one of the two primary divisions of life. Unicellular organisms lacking a nucleus, possessing distinctive ribosomes and initiator tRNA, and generally containing peptidoglycan in the cell wall.
Archaea
one of the two primary divisions of life. Often used for only prokaryotic archaea, which are unicellular organisms that lack a nucleus and lack peptidoglycan in the cell wall. Likely related to lokiarchaeota
Eukaryotes
a group of organisms made up of one or more complex cells in which the genetic material is contained in nuclei. Includes plants, fungi, and animals.
Nucleus
in cells: the centrally located compartment of eukaryotic cells that is bounded by a double membrane and contains the chromosomes
Metabolism
the sum total of the chemical reactions that occur in an organism, or some subset of that total (as respiratory metabolism)
Photosynthesis
the metabolic process carried out by green plants and some microorganisms by which visible light is trapped and the energy used to synthesize compounds such as ATP and glucose.
Cyanobacteria
a group of unicellular, colonial, or filamentous bacteria that conduct photosynthesis using chlorophyll
Aerobic metabolism
occurring in the presence of oxygen
Anaerobic metabolism
occurring without the use of molecular oxygen
Cellular specialization
in multicellular organisms, the division of labor such that different cell types become responsible for the different functions (e.g. reproduction or digestion) within the organism
Tissues
a group of similar cells organized into a functional unit; usually integrated with other tissues to form part of an organ
Organs
a body part, such as the heart, liver, brain, root, or leaf. Organs are composed of different tissues integrated to perform a distinct function. Integrated into organ systems
Organ systems
an interrelated and integrated group of tissues and organs that work together in a physiological function
Internal environment
in multicellular organisms, the extracellular body fluids (interstitial/tissue) that bathe the cells of the body and therefore constitute the immediate environment of the cells
Homeostasis
the maintenance of a steady state, such as a constant temperature, by means of physiological or behavioral feedback responses
Sensory mechanisms
the means by which internal or external stimuli are converted into neural signals
Effector mechanisms
adaptations that enable an organism to alter its physiological or behavioral state
Signaling mechanisms
the means of transferring information between cells, organs, and organisms
Community
a group of species living together at the same time and place
Ecosystem
the organisms of a particular community together with the physical and chemical environment in which they live
Biomes
a major division of the ecological communities of Earth, characterized primarily by distinctive vegetation and annual patterns of temperature and precipitation.
Biosphere
all regions of Earth (terrestrial and aquatic) and Earth's atmosphere in which organisms can live
Genes
a unit of heredity. Used as the unit of gene function that carries the information for a polypeptide or RNA
Genetics
the scientific study of the structure, functioning, and inheritance of genes
Deoxyribonucleic acid (DNA)
the fundamental hereditary material of all living organisms. In eukaryotes, stored primarily in the cell nucleus. A nucleic acid using deoxyribose rather than ribose
Genome
the complete DNA sequence for a particular organism or individual
Nucleotides
the basic chemical unit in nucleic acids, consisting of a pentose sugar, a phosphate group, and a nitrogen-containing base
Transcribing
the synthesis of RNA using one strand of DNA as a template
Ribonucleic acid (RNA)
an often single-stranded nucleic acid whose nucleotides use ribose rather than deoxyribose and in which the base uracil replaces thymine found in DNA. seres as a genome for some viruses
Mutations
a change in the genetic material not caused by recombination
Population
any group of organisms coexisting at the same time and in the same place and capable of interbreeding with one another
Natural selection
the different contribution of offspring to the next generation by various genetic types belonging to the same population. The mechanism of evolution proposed by Charles Darwin
Adaptations
In evolutionary biology, a particular structure, physiological process, or behavior that makes an organism better able to survive and reproduce. Also, the evolutionary process that leads to the development or persistence of such a trait
Genomics
the scientific study of entire sets of genes and their interactions
Bioinformatics
the use of computer programs and mathematical approaches to analyze complex biological data, such as DNA sequences
Phylogenetic trees
a graphic representation of the lines of descent among organisms or their genes
Binomial
a taxonomic naming system in which each species is given a binomial, a genus name followed by a species name
Genus
a group of related, similar species recognized by taxonomists with a distinct name used in binomial nomenclature
Data
quantified observations about a system under study
Inductive logic
a logical thought process that involves making observations and then formulating one or more hypotheses that might explain those observations
Hypothesis
a tentative answer to a question, from which testable predictions can be generated
Deductive logic
a logical thought process that starts with a premise believed to be true, then predicts what facts would also have to be true to be compatible with that premise
Controlled experiments
manipulate one factor of interest while holding other variables constant as a means of testing the influence of the manipulated variable
Comparative experiments
compare data gathered from different populations that differ in multiple, unknown ways
Null hypothesis
the premise that any differences observed in an experiment are simply the result of random differences that arise from drawing two finite samples from the same population\
Model systems
the small group of species that are the subject of extensive research. Organisms that adapt well to laboratory situations, and findings from experiments on them can apply across a broad range of species (e.g., mice, zebrafish, fruit flies, and e. coli)
Cell theory
the theory that cells are the basic structural and physiological units of all living organisms, and that all cells come from preexisting cells
Surface area-to-volume ratio
for any cell, organism, or geometrical solid, the ratio of surface area to volume; this is an important factor in setting an upper limit on the size a cell or organism can attain
Cell membrane
the membrane that surrounds the cell, regulating the entry and exit of molecules and ions. Every cell has a cell membrane
Cytoplasm
the contents of the cell, excluding the nucleus
Cytosol
the fluid portion of the cytoplasm, excluding organelles and other solids
Prokaryotes
unicellular organisms that do not have nuclei or other membrane-enclosed organelles
Eukaryotes
organisms whose cells contain their genetic material inside a nucleus. Includes all life other than viruses, archaea, and bacteria
Organelles
any of the membrane-enclosed structures within a eukaryotic cell. E.g., nucleus, endoplasmic reticulum, mitochondria, etc.
Nucleus
the centrally located compartment of eukaryotic cells that is bounded by a double membrane and contains the chromosomes
Nucleoid
the region that harbors the chromosomes of a prokaryotic cell. NOT bound by a membrane
Ribosomes
small particles in the cell that are the sites of protein synthesis
Cell wall
a relatively rigid structure that encloses cells of plants, fungi, many protists, and most prokaryotes, and which gives these cells their shape and limits their expansion in hypotonic media
Outer membrane
in organelles that have two membranes such as chloroplasts and mitochondria, the outer membrane encloses the entire organelle
Capsule
in some prokaryotes, a dense layer of polymers that surrounds the cell wall
Internal membrane
a membrane that is enclosed within a membrane-bound organelle. E.g., the membrane around thylakoids in chloroplasts and the inner mitochondrial membrane.
Flagella
a long, whiplike appendage that propels cells. Prokaryotic flagella differ greatly from eukaryotes
Pili
a structure that links prokaryote cells at the beginning of conjugation
Cytoskeleton
the network of microtubules and microfilaments that gives a eukaryotic cell its shape and its capacity to arrange its organelles and move
Nucleolus
a small, generally spherical body found within the nucleus of eukaryotic cells. The site of synthesis of ribosomal RNA
Nuclear envelope
a double membrane that encloses the cell nucleus
Chromatin
the nucleic acid-protein complex that makes up eukaryotic chromosomes
Chromosomes
in bacteria and viruses, the DNA molecules that contain most or all of the genetic information of the cell or virus. In eukaryotes, a structure composed of DNA and proteins that bear part of the genetic information of the cell
Endomembrane system
a system of intracellular membranes that exchange material with one another, consisting of the Golgi apparatus, endoplasmic reticulum, and lysosomes when present
Vesicles
within the cytoplasm, a membrane-enclosed compartment that is associated with other organelles; e.g., Golgi apparatus
Endoplasmic reticulum (ER)
a system of membranous tubes and flattened sacs found in the cytoplasm of eukaryotes. Rough ER: ribosomes, smooth ER: no ribosomes
Golgi apparatus
a system of concentrically fouled membranes found in the cytoplasm of eukaryotic cells; function in secretion from the cell by exocytosis
Primary lysosomes
a lysosome before fusion with an endosome
Phagocytosis
the process by which a cell uses its cell membrane to enclose and engulf a macromolecule or particle in the extracellular environment
Secondary lysosome
a membrane-enclosed organelle formed by the fusion of a primary lysosome with a phagosome, in which macromolecules are taken up by phagocytosis are hydrolyzed into their monomers
Exocytosis
a process by which a vesicle in a cell fuses with the cell membrane and releases its contents to the outside
Autophagy
the programmed destruction of a cell's components
Lysosomal storage diseases
a class of human diseases, invariably harmful or fatal, that are caused by the failure of lysosomes to digest specific cellular components. E.g., Tay-Sachs disease
Mitochondria
energy-generating organelles in eukaryotic cells that contain the enzymes of the citric acid cycle, the respiratory chain, and oxidative phosphorylation
Chloroplasts
an organelle bounded by a double membrane containing the enzymes and pigments that perform photosynthesis. Occur ONLY in eukaryotes
Thylakoids
a flattened sac within a chloroplast. Contain all of the chlorophyll in a plant, in addition to the electoral carriers of photophosphorylation. Stack together to form grana
Peroxisomes
an organelle that houses reactions in which toxic peroxides are formed and then converted to water
Glyoxysomes
a plant organelle in which stored lipids are converted to carbohydrates
Vacuoles
a membrane-enclosed organelle in plant cells that can function for storage, water concentration for turgor, or hydrolysis of stored macromolecules
Microfilaments
in eukaryotic cells, a fibrous structure made up of actin monomers. Play roles in the cytoskeleton, cell movement, and muscle contraction
Actin
a protein that makes up the cytoskeletal microfilaments in eukaryotes and is one of two contractile proteins in muscles
Intermediate filaments
a part of the cytoskeleton that includes filament intermediate in diameter between microtubules and microfilaments
Microtubules
tubular structures found in the centrioles, spindle apparatus, cilia, flagella, and cytoskeleton of eukaryotes. Play roles in the motion and maintenance of the shape of eukaryotes
Tubulin
a protein that polymerizes to form microtubules
Motor proteins- specialized proteins that use energy to change shape and move cells or structures within cells
Kinesins
a type of protein that binds to microtubules and vesicles. By moving along microtubules, kinesins act as motor proteins to move attached vesicles
Dyneins
a type of protein that binds to microtubules and causes bending in cilia and flagella
Cilia
hairlike organelles used for locomotion by many unicellular organisms and for moving water and mucus by many multicellular organisms. Generally shorter than flagella
Plasmodesmata
in plants, membrane-lined channels that extended through the cell walls and connect the cytoplasm of adjacent cells