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pathology
the study of disease
disease
abnormal disturbance in body structure and function
pathogenesis
origin of a disease
syndrome
a group of signs that labels a condition
symptom
subjective/how you feel
sign
objective/can visually see
etiology
causes of a disease
iatrogenic
result of a medical treatment
idiopathic
unknown cause
diagnosis
assigning a name of the disease
prognosis
predicted outcome
osteolytic disease
subtractive vs objective (takes away)
osteoblastic disease
additive vs sclerotic (adds bone mass)
congenital
occurs in utero, present at birth
hereditary
genetic
inflammatory
heat, swelling, pain, redness, loss of function
degenerative
caused by deuteriation of the body
metabolic
disturbance of the normal physiologic functions of the body
neoplastic (tumor)
new, abnormal tissue growth, benign vs malignant
fibroma
fibrous tissue
chondroma
cartilage
adenoma
glandular (covers the organs/glands)
lipoma
fatty
myoma
muscle
hemangioma
busted blood vessels
polyps
if not removed, could be cancerous
characteristics of a malignant tumor
grow, invade and spread
myeloma
blood cells in the bone marrow
leukemia
cancer in blood cells that spread through the blood stream
sarcoma
malignant (bone, muscle or cartilage)
the four types of metastatic spread
hematogenous, lymphatic, invasion, seeding
hematogenous
blood cells that break off, travel by blood stream
lymphatic
lymph tissue
invasion
because of close proximity to another structure
seeding
distant tissues
abscess
puss (tissue of the body)
effusion
joints (air-fluid levels)
edema
fluid in the tissues
ischemia
restriction of blood flow to the bodies tissues
type of ischemia
cardiac, brain, intestinal, limb
cardiac ischemia
coronary artery (atherosclerosis)
brain ischemia
stroke
intestinal ischemia
embolism, necrosis (infarct)
limb ischemia
peripheral artery disease/gangrene
hemorrhage
active, on-going blood loss/ internal or external
hematoma
collection of clotted blood inside of the blood vessels (causes by injury or trauma, normally a bruise under the skin)
atrophy
the physiological process of reabsorption and breakdown of tissues
3 types of atrophy
physiologic, pathologic, neurogenic
dysplasia
abnormal development of cells within tissues
3 types of dysplasia
hyperplasia, hypoplasia, aplasia
number of bones in the skeletal system
206
2 types of skeletal systems
appendicular and axial
very dense surface layer of all bones
compact
joint structure and function types
fibrous- synarthrodial, cartilaginous- amphiarthrodial, synovial- diarthrodial
3 types of bone cells and their function
osteoblasts- form, osteoclasts - remove, osteocytes - maintain
3 types of blood cells found in bones
erythrocytes, leukocytes and platelets
what is the organic and inorganic substance of bone
inorganic- calcium, organic- collagen
another name for spongy bone
cancellous bone
process by which bone is continually replaced by new bone
bone remodeling
what is considered a symptom of a disease process
pain
a compression fracture of the lumbar space that results from steroid treatments for a pain would be what type of disease
iatrogenic
the process of assigning a name to a patients condition
diagnosis
7 categories used for disease classification
congenital, heredity, inflammatory, degenerative, metabolic, traumatic and neoplastic
a disease such as cystic fibrosis is transmitted by a parent
hereditary
5 clinical signs of inflammation
heat, pain, swelling, redness and loss of function
degenerative disease caused by aging
osteoarthritis
inflammatory disease caused by high levels of uric acid in the blood
gout
difference between malignant and benign
malignant- cancerous, benign- noncancerous
4 ways in which malignant neoplasms metastasize
hematogenous, lymphatic, seeding and invasion
what congenital pathologic condition is present if the posterior elements of one of more vertebrae fail to unite
spina bifida
an inherited disorder of connective tissue characterized by multiple fractures and bluish color of the sclera of the eye
osteogenesis imperfecta
a possible cause would be an open fracture
osteomyelitis
most common form of dwarfism
achondroplasias
medical term used for clubfoot
talipes equinovarus
pathology in young children resulting in the failure of the femoral head to sit correctly within the acetabulum
congenital hip dysplasia
what is the most common type of osteogenesis imperfecta
type 1
another name for osteopetrosis
marble bone
what is the genetic disorder called where you cannot separate your fingers
syndactylism
what is the presence of extra digits
polydactylism
what is another name for clubfoot
talipes equinovarus
what disorder makes your toes pull medially
clubfoot
what disorder results from incomplete articulation of the femoral head with the acetabulum
congenital hip dysplasia
where is the most common extra rib found
cervical spine
what is the failure of the posterior elements to fuse properly
spina bifida
how many types of spina bifida are there
3
what is the mildest type of spina bifida
spina bifida occulta
what kind of spina bifida does not include the spinal cord
meningocele
what is the most common type of spina bifida
myelomeningocele
what percentage of spina bifidas are myelomeningocele
70%
what is a result of spina bifida (80% of people will get this)
hydrocephalus
what is the inflammation of the bone and the bone marrow that is caused by infectious organisms that reach the bone
osteomyelitis
what type of inflammatory disease is bacterial
osteomyelitis
disease with inflammatory changes occurring throughout the body’s connective tissue
rheumatoid arthritis
what inflammatory disease is a chronic autoimmune disease
rheumatoid arthritis
non-inflammatory disease charactered by gradual deterioration of the articular cartilage
osteoarthritis
what is the most common type of arthritis
osteoarthritis
what disease is caused by the development of osteophytes along margins of the articular edges of the bone
osteoarthritis
disease that develops in people who have high levels of uric acid in their blood
gout
what joint is most frequently attacked by gout
MTP joint
natural part of aging, decrease in bone density
osteoporosis