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integument (skin)
a vital organ serving as a protective barrier that responds to internal and external stimuli and contributes to the maintenance of homeostasis
specialized tissue
hair, nails, sebaceous (oil), sudoriferous (sweat) glands, and mammary glands
9 pounds
What is the weight of skin?
18 square feet (of an adult)
How much of the body is covered in skin?
epidermis (cuticle)
the outermost, nonvascular layer of the skin; composed of, from within outward, five layers: basal layer, prickle-cell layer, granular layer, clear layer, and horny layer
dermis corium
layer of the skin deep in the epidermis, consisting of a dense bed of vascular connective tissue and containing the nerves of terminal organs or sensation, the hair roots, and sebaceous and sweat glands
hair, nails
appendages of the skin
subcutaneous
beneath the skin, containing adipose tissue, connective tissue, blood vessels, and nerves
breast
mammary glands; in female mammals, the breast contains milk-secreting elements for nourishing the young
squamous epithelium
a layer of flattened plate-like cells that cover internal and external body surfaces
stratum basale
in this layer of skin, new cells are formed and push older cells to the outermost surface of the skin
stratum corneum
outermost layer of skin where dead cells are converted to keratin, which flakes away
protection
from microorganisms, injuries, and excessive exposure to ultraviolet rays of the sun
sensory organs
for the body to feel pain, cold, heat, touch, and pressure
temperature regulator
insulation against heat and cold, e.g., perspiration for cooling
metabolism
in the presence of sunlight, synthesize vitamin D from a precursor molecule found in the skin
water elimination
eliminate body wastes in the form of perspiration
carcinoma
a malignant new growth made up of epithelial cells tending to infiltrate surrounding tissues and give rise to metastases
Keratosis
any horny growth such as a wart or callosity
Malignant melanoma
cancerous tumor of melanin-forming cells of the skin; changes in the appearance of a mole may indicate melanoma
nevus
a mole or growth
steatoma
lipoma; a fatty mass retained within a sebaceous gland; sebaceous cyst
verruca
a wart caused by viruses; a plantar wart is on the sole or plantar surface of the foot
acne vulgaris
develops when skin pores become clogged with dead skin cells because of excess production of sebum (oil) causing dead skin cells to stick together and clog the pore. Bacteria in the clogged pore causes inflammation and the formation of a cyst
furuncle
pus-filled bumps that form under the skin when staphylococcal bacteria infect hair follicles (boil)
carbuncle
a cluster of furuncles that form a connected area (track) of infection under the skin
cellulitis
inflammation of the skin and subcutaneous tissue caused by streptococcal or staphylococcal bacteria as a result of a break in the skin from injury, surgery, or an insect bite; may lead to ulceration and abscess
impetigo
a streptococcal or staphylococcal skin infection marked by vesicles or bullae that become pustular, rupture, and form yellow crusts, especially around the mouth and nose
MRSA (methicillin-resistant staphylococcus aureus)
skin infection caused by bacteria resistant to treatment with methicillin and other antibiotics
rosacea
common skin condition with redness and visible blood vessels of the nose and cheek that slowly spread to the forehead and chin, and eventually form small pus-filled bumps similar to acne. More common in those with fair skin or a history of acne
Herpes
inflammatory skin disease caused by a herpes virus; acute symptoms are small blisters that appear in clusters; can be a chronic condition with periods of remission
herpes genitalis
herpes infection (HSV-2) of the genitals; may harm an infant if the mother is infected at the time of delivery
herpes ophthalmicus
severe herpes zoster involving the ophthalmic nerve (eye)
herpes simplex virus (HSV)
herpes infection (HSV-1) on the borders of the lips or nares (cold sores)
herpes zoster (shingles)
painful rash on one side of the body caused by varicella zoster virus (VZV), the virus that causes chickenpox; virus is dormant in those who have had chickenpox but often reappears as shingles in those over 60 years of age or those who are immunocompromised
Roseola (sixth disease)
illness common in children from birth to 2 years of age; symptoms begin with a high fever followed by a red-colored skin rash; caused by herpesvirus 6 (HHV-6) and possibly herpesvirus 7 (HHV-7)
verruca
growth of the outer layer of the skin (the epidermis) caused by the human papillomavirus (HPV) and transmitted by human contact.
tinea
called ringworm because of the circular shape of the rash (shaped like a ring); a name applied to many different superficial fungal infections of different parts of the body
tinea barbae
infection of the bearded parts of the face by ringworm
tinea capitis
infection of the scalp by ringworm
tinea corporis
infection of the entire body by ringworm
tinea cruris
infection of the groin area by ringworm
tinea pedis
athlete’s foot; a chronic superficial infection of the skin of the foot by ringworm
tinea unguium
infection of the fingernails by ringworm; the nails become opaque, white, thickened, and friable
pediculosis
body infestation with lice, usually of the scalp and pubic area; lice suck blood from humans causing itching and infection secondary to scratching
pediculosis capitis
head lice
pediculosis corporis
body lice
pediculosis pubis
pubic lice or crabs
scabies
caused by a mite, a small parasite that burrows under the skin; symptoms are an itchy rash
allergic contact dermatitis
itchy, blistering rash after contact with poison ivy, oak, or sumac; other causes are latex gloves or jewelry containing nickel
atopic dermatitis (eczema; AD)
common skin condition in children during the first year of life; dry, scaly, and itchy patches appear on the scalp, forehead, and fac
contact dermatitis
skin reaction which appears as an itchy rash in response to contact with a skin irritant, e.g., diaper rash or dry, cracked hands because of frequent contact with water, e.g., bartenders, hairdressers, and housekeeping workers
neurodermatitis
skin condition that begins with itching related to emotional causes or psychological factors
Coccidioidomycosis (Valley Fever)
fungal infection of the lungs caused by inhaling spores of the fungus, Coccidioides, which lives in the soil; symptoms include flu-like symptoms and red bumps on the skin
erysipelas (St. Anthony’s fire)
a contagious disease of the skin and subcutaneous tissues caused by infection with Group A Streptococci organisms; complication of strep throat, surgical wound, or skin injury; redness and swelling of affected areas
histoplasmosis
a systemic fungal disease caused by inhalation of dust contaminated by spores of the fungus, Histoplasma, which lives in soil that contains large amounts of bird or bat droppings. Symptoms include flu-like symptoms; red bumps appear on the lower legs in some patients
Lyme Disease
inflammatory disease with early symptoms of a characteristic circular red rash and flu-like symptoms; caused by bacteria and transmitted by deer tick bites. Later complications can be arthritis and neurological and cardiac disorders
psoriasis
a chronic, hereditary, recurrent dermatosis marked by discrete vivid red macules, papules or plaques covered with silvery laminated scales
Rocky Mountain Spotted Fever (RMSF)
symptoms are small, flat, pink, non-itchy spots (macules) on the wrists, forearms, and ankles which can spread to the trunk, palms and soles. Transmitted by tick bites and caused by bacterium Rickettsia rickettsia; if untreated, complications include organ failure and death
Rubella (german measles)
early symptoms are a rash that starts on the face and spreads to the rest of the body; later symptoms can include a low-grade fever, cough, runny nose, sore throat, and pink eye
rubeola (measles)
symptoms are fever, runny nose, cough, red eyes, and sore throat, followed by a rash that spreads over the body. The disease is very contagious and is spread through air from coughing and sneezing
syphilis
a sexually transmitted bacterial disease; early skin symptoms are ulcers on the genital area, followed by white patchy skin
systemic lupus erythematosus (SLE)
autoimmune disease that can affect all organs; common symptom is a rash that forms a butterfly pattern over the bridge of the nose and cheeks
varicella (chicken pox)
a very contagious disease caused by the varicella-zoster virus (VZV); symptoms are blister-like rash, itching, fatigue, and fever
actinic keratosis (AK)
precancerous patch of thick, scaly, or crusty skin; usually forms when skin is damaged by ultraviolet (UV) radiation exposure from the sun or indoor tanning beds
albinism
no body pigment; white skin and hair
alopecia
baldness; hereditary or caused by chemotherapy
bulla
large blisters, as in burns
burn
thermal injury to tissues
first-degree burns
often caused by sunburn, affect the top skin layer (corneum) and show redness
second-degree burns
burns affect the upper three skin layers (corneum, lucidum, and granulosum) and produce blisters between the third and fourth skin layer
Third-degree burn
affect the top three layers plus the fourth layer (germinativum) with fluid loss, risk for infection, and require skin grafting
callus
localized hyperplasia of the horny layer of the epidermis (skin) caused by pressure or friction; most common sites are the hands and feet
cicatrix
a scar
cyst
a closed epithelium-lined cavity or sac, normal or abnormal, usually containing liquid or semisolid material
ecchymosis
bruise, caused by bleeding under the skin
erosion
eating or gnawing away; an early ulcer
eruption
breaking out; a rash
erythema
redness of the skin
eschar
a slough (hard crust) produced by a thermal burn
exanthem
an eruptive (rose colored) skin rash caused by disease or fever
excoriation
a superficial loss of skin
exfoliation
skin falling off in scales or layers
gangrene
necrotic or dead tissue
hemangioma
network of small blood-filled capillaries near the surface of the skin forming a reddish or purplish birthmark; may appear in newborn infants
hirsutism
abnormal hairiness on the body and face, especially in women
keloid
a sharply elevated, progressively enlarging scar that does not fade with time
laceration
cut; tearing; a torn wound
lesion
any pathologic or traumatic discontinuity of tissue, e.g., a sore
macule
a spot or thickening, e.g., freckle, flat mole. Area is not raised above the surface
miliaria (prickly heat; heat rash)
inflammatory disorder of the skin characterized by redness, eruption, and burning or itching due to blockage of the ducts of the sweat glands; common in hot and humid climates
nodule
a small node that is solid and can be detected by touch; a rounded prominence
nummular
coin-shaped skin sores; often appear after a burn or skin injury
papulae
a small, circumscribed, solid elevated lesion of the skin, e.g., wart, acne, mole
paronychia
inflammation of the folds of tissue around the fingernail
petechia
small pinpoint hemorrhages of the skin, red or purple in color
plaque
any patch or flat area; used to describe the silvery scales of psoriasis
pruritus
itching
pustule
a small, elevated, pus-containing lesion of the skin
scales, crusts
an outer layer formed by drying of a bodily exudate or secretion; flaking type of lesion, e.g., psoriasis, fungus