Systems Path Section 6 - Pulmonary Vascular Pathology (pg 80-end)

DVT which travels to pulmonary circulation and occludes vessels

pulmonary embolism

risks associated with a developing pulmonary embolism

immobility, CHF, oral contraceptive

symptoms of pulmonary emboli

acute dyspnea, cough, chest pain, hemoptysis, cyanosis, collapse

what type of embolism causes >60% occlusion causing circulatory collapse -> shock

saddle embolism

25+ mm/Hg in pulmonary circulation leading to increased edema and pulmonary effusion, along with right sided heart failure

pulmonary hypertension

how does pulmonary hypertension develop?

fibrosis, decreased pulmonary ventilation, left-to-right shunt in heart

who is most likely to develop pulmonary hypertension

anyone with risks

risk associated with pulmonary hypertension

chronic lung disease, autoimmune, CHF, shunts

what type of pulmonary HTN is thought to be caused by endothelia dysfunction, vascular fibrosis and smooth muscle hyperplasia?

primary

primary pulmonary HTN is MC in who?

young females

symptoms of primary pulmonary HTN

dyspnea, fatigue, cyanosis, angina, cor pulmonale

group of diseases that cause pulmonary hemorrhage

diffuse alveolar hemorrhage syndromes (DAHS)

Diffuse alveolar hemorrhage triad

hemoptysis, anemia, diffuse pulmonary edema

what DAHS is a type 2 hypersensitivity in 20-30 year old males and 60-70 year old females causing pulmonary infiltrates?

good pasture syndrome

what DAHS is a type 4 hypersensitivity which occurs in 40 year old males and results in rash, myalgia and arthritis?

wegener's granulomatosis

what do Wegener and goodpasture have in common?

both cause hemoptysis and hematuria