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Substantia nigra
Dopamine production & delivery to the BG (movement, Parkinson's)
Parkinson's Disease
Atrophy of neurons and glia in the substantia nigra (of the midbrain) which produces dopamine
Ventral Tegmental Area (VTA)
Dopamine production & delivery to frontal lobes (executive functions) nucleus accumbens (pleasure) and hippocampus (memory)
Reticular Formation
Levels of alertness
Cerebral Peduncles
Motor tracts that go from the cortex through midbrain on the way to the lower brain structures & the spinal cord
Superior Colliculi
Control of eye movements and orientation of eyes and head toward visual stimuli
Inferior Colliculi
Auditory localization, orientation to auditory stimuli, and startle response to loud sounds
Cerebellum
10% of brain by volume, but 80% of brain neurons
Cerebellar Functions
Coordination, precision, and timing of movement (cerebellar ataxia = drunk-like symptoms)
Gait
Staggering, wide gait
Balance
Falling, wide gait
Intension tremors
As we saw with the disorder known as Essential Tremor
Nystagmus
Involuntary back and forth eye movements
Vestibulo-Optic Reflex (VOR)
Stabilizing vision during head movements
Cerebellum
Areas involved in functions such as abstract thinking, planning, emotion, memory and language.
Cerebellar Functions
Quality control (fine tuning) of movement and cognitive functions
Cerebellum
Constantly reviewing and improving a person's thoughts and decisions
Cerebellar Additional Functions
The cerebellum makes motor and cognitive processes smoother and faster and more accurate.
Physical Bases of ASD
Significantly fewer cerebellar Purkinje cells.
Pons
Motor plan originates in the frontal lobes
Raphe nucleus of the pons
Produces much of the brain’s serotonin
Locus coeruleus of the pons
Produces much of the brain’s norepinephrine
Medulla
Controls Vital Functions
Medulla
Breathing
Medulla
Heart Rate
Medulla
Blood Pressure
Medulla
Vomiting (sneezing, coughing, & swallowing)