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ATP
Adenosine Triphosphate
energy currency of the cell - stores energy that can be used to do cellular work
Catabolic
breaks down cellular structures
harvests energy stored in food or fat cells
Digestion
break down of food into molecules that are small enough for your body to absorb
provide nutrients for respiration
aerobic respiration
process to convert stored energy (glucose) to ATP when oxygen is present
O2 is the final electron acceptor in the ETC
Anaerobic respiration
method of harnessing chemical energy without oxygen; typically only done in prokaryotes
final electron acceptor in ETC is another inorganic molecule less electronegative compared to oxygen
Faculative Anaerobes
Use aerobic respiration most of the time but can function without O2 through fermentation
muscle cells
Obligate anaerobes
Cannot function in the presence of O2
Fermentation
catabolic reaction that continously oxidizes NADH to form NAD+ and transfers electron to pyruvate (or pyruvate derivative) that can fuel glycolysis
happens in the cytosol of the cell and produces 2 ATP
Ethanol / Ethyl Alcohol
product of Alcohol Fermentation that is performed by yeast and bacteria
Lactate / Lactic Acid
Product of Lactic Acid fermentation
done by bacteria, fungi, & human muscle cells
Autotrophs
organisms that create their own organic molecules from inorganic molecules
photoautotrophs
use light energy to make food
chemotrophs
use other methods to other than light to make food
Heterotrophs
organisms that gain energy by breaking down other organisms
Substrate-level phosphorylation
ATP forms through direct transfer of organic phosphate (created during reaction) to ADP using enzyme
- glycolysis and Kreb’s Cycle
Oxidative Phosphorylation
Process that combines P and ADP to make ATP using energy from the redox reactions of the ETC
Glycolysis
process to convert Glucose into Pyruvate
First step of Respiration that happens in cytosol
nets 2 ATP
Nicotimide Adenine Dinucleotide (NAD+)
electron acceptor that converts to NADH and shuttles the electrons to where it needs to go (ETC)
phosphofructokinase
3rd enzyme of glycolysis that is key for regulating the production of ATP in the cell based on the inhibition of other molecules
Pyruvate
product of glycolysis that is where most of the energy from glucose gets stored.
ionized form of pyruvic acid
Acytel-CoA
product of pyruvate oxidation
links glycolysis and citric acid cycle
Citric Acid Cycle / Kreb’s Cycle
converts Acetyl-CoA to regenerate oxaloacetate in the mitochondrial matrix
Citrate synthase
first enzyme in citric acid cycle that limits the rate of production in the cycle
provides citrate from acetyl CoA which in high amounts inhibits phosphofructokinase
electron transport chain (ETC)
transfer of electron down a chain of organic molecules (redox reactions) found in cristae until it gets to O2. Releases energy that can be used to make a proton gradient between intermembrane space and matrix
NADH Dehydrogenase
Enzyme that removes 2H from NADH to form NAD+
First complex in the electron transport chain
Cytochromes
protein containing a heme (iron) prosthetic group that accepts and transfers electron in the ETC
Chemiosmosis
Process in which energy stored in energy gradient after ETC is used to drive ATP synthesis using enzyme ATP synthase
ATP Synthase
enzyme that makes ATP using energy from a proton gradient between the mitochondrial innermembrane space (high concentration) and matrix (low concentration)
Beta-oxidation
break down of fatty acids into 2-carbon fragments that can enter the citric acid cycle as Acetyl-CoA